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A molecularly imprinted fluorescence nanosensor based on upconversion metal–organic frameworks for alpha-cypermethrin specific recognition

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Abstract

A sensitive molecularly imprinted fluorescent nanosensor based on zeolitic imidazolate frameworks-8 (ZIF-8) and upconversion nanoparticles (UCNPs) was developed for the determination of trace alpha-cypermethrin (α-CPM) for the first time. The sensor was synthesized by a layer-by-layer self-assembly strategy. UCNPs with a maximum emission wavelength of 544.5 nm under 980 nm excitation were firstly prepared as the luminous core. Then, ZIF-8 with the large specific surface and porosity was introduced, which not only improved the mass transfer and adsorption capacity of the sensor but also increased the fluorescence intensity of UCNPs as a protective layer. Finally, molecularly imprinted polymers (UCNPs@ZIF-8@MIPs) were fabricated in mixed solutions containing UCNPs@ZIF-8 (support material), α-CPM (template), acrylamide (functional monomer), and divinylbenzene (cross-linker). Under the optimal condition, the fluorescence intensity of UCNPs@ZIF-8@MIP was linearly quenched with increasing concentration of α-CPM in the range 0.10–12 mg L−1 with a detection limit of 0.03 mg L−1 (S/N = 3). The developed UCNPs@ZIF-8@MIP probe was used to detect α-CPM in real samples; the satisfactory results obtained were consistent with those obtained by GC-MS.

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Funding

This work was supported by the National Key Research and Development Program of China (project No. 2017YFC1600803) and the Project of Tianjin Science and Technology Plan (No. 19PTSYJC00050).

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Authors and Affiliations

  1. State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin, 300457, China

    Xuelian Hu, Yichuan Cao, Yanyan Tian, Ying Qi, Guozhen Fang & Shuo Wang

  2. Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University (BTBU), Beijing, 100048, China

    Shuo Wang

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  1. Xuelian Hu
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  2. Yichuan Cao
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  4. Ying Qi
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Correspondence to Guozhen Fang or Shuo Wang.

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Hu, X., Cao, Y., Tian, Y. et al. A molecularly imprinted fluorescence nanosensor based on upconversion metal–organic frameworks for alpha-cypermethrin specific recognition. Microchim Acta 187, 632 (2020). https://doi.org/10.1007/s00604-020-04610-2

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