Abstract
Purpose
Osteointegration of a three-dimensional (3D) porous titanium material has been experimentally proven, but only a few studies have shown the clinical outcomes of a 3D porous titanium cup in the Japanese elderly population. The purpose of this study was to compare the short-and-medium term clinical and radiographic results of total hip arthroplasty (THA) using a 3D porous titanium cup in patients aged ≥ 80 (octogenarians) versus those aged < 80 (younger controls).
Methods
A total of 104 hips that underwent THA using a 3D porous titanium cup (SQRUM TT, Kyocera Medical) were enrolled in the study and were divided into two groups according to age: the octogenarian group (≥ 80, n = 42) and the younger control group (< 80, n = 62). Furthermore, we evaluated patient characteristics, clinical outcomes determined by the Japanese Orthopedic Association score, cup alignment, and incidence of radiolucent lines around the cup.
Results
The mean follow-up period was 4.2 and 4.0 years (p = 0.29) for octogenarians and younger controls, respectively. The clinical outcomes were excellent, and no revision surgery occurred until the last follow-up in both groups. The number of patients with radiolucent lines at the final evaluation was 21 of 62 (33.9%) in younger controls and 16 of 42 (38.1%) in octogenarians.
Conclusion
THA with 3D porous titanium cup for octogenarians had similar clinical outcomes and incidence of radiolucent lines as those of younger controls, suggesting that the 3D porous titanium cup may be useful in THA for octogenarians. Further investigations will confirm its long-term outcomes.
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Data availability
All data generated or analyzed during this study are included in this published article.
References
Christensen K, Doblhammer G, Rau R, Vaupel JW (2009) Ageing populations: the challenges ahead. Lancet 374(9696):1196–1208
Kontis V, Bennett JE, Mathers CD, Li G, Foreman K, Ezzati M (2017) Future life expectancy in 35 industrialised countries: projections with a Bayesian model ensemble. Lancet 389(10076):1323–1335
Japanese orthopaedic association national registry. https://jsra.info/about/surveyreport/. Accessed 24 Mar 2022
Murphy BPD, Dowsey MM, Spelman T, Choong PFM (2018) What is the impact of advancing age on the outcomes of total hip arthroplasty? J Arthroplast 33(4):1101-1107.e1
Fang M, Noiseux N, Linson E, Cram P (2015) The effect of advancing age on total joint replacement outcomes. Geriatr Orthop Surg Rehabil 6(3):173–179
Yoshihara H, Yoneoka D (2014) Trends in the incidence and in-hospital outcomes of elective major orthopaedic surgery in patients eighty years of age and older in the united states from 2000 to 2009. J Bone Jt Surg Am 96(14):1185–1191
Apostu D, Piciu D, Oltean-Dan D, Cosma D, Lucaciu O, Popa C, Mester A, Benea H (2022) How to prevent aseptic loosening in cementless arthroplasty: a review. Appl Sci 12(3):1571
Ogino D, Kawaji H, Konttinen L, Lehto M, Rantanen P, Malmivaara A, Konttinen YT, Salo J (2008) Total hip replacement in patients eighty years of age and older. J Bone Jt Surg Am 90(9):1884–1890
Geng X, Li Y, Li F, Wang X, Zhang K, Liu Z, Tian H (2020) A new 3D printing porous trabecular titanium metal acetabular cup for primary total hip arthroplasty: a minimum 2-year follow-up of 92 consecutive patients. J Orthop Surg Res 15(1):383
Massari L, Bistolfi A, Grillo PP, Borré A, Gigliofiorito G, Pari C, Francescotto A, Tosco P, Deledda D, Ravera L, Causero A (2017) Periacetabular bone densitometry after total hip arthroplasty with highly porous titanium cups: a 2-year follow-up prospective study. Hip Int 27(6):551–557
De Meo F, Cacciola G, Bellotti V, Bruschetta A, Cavaliere P (2018) Trabecular titanium acetabular cups in hip revision surgery: mid-term clinical and radiological outcomes. Hip Int 28(2_suppl):61–65
Hoskins W, Rainbird S, Holder C, Graves SE, Bingham R (2022) Revision for aseptic loosening of highly porous acetabular components in primary total hip arthroplasty: an analysis of 20,993 total hip replacements. J Arthroplast 37(2):312–315
Levine B (2008) A new era in porous metals: applications in orthopaedics. Adv Eng Mater 10(9):788–792
Yoshimoto K, Nakashima Y, Wakiyama M, Hara D, Nakamura A, Iwamoto M (2018) Initial stability of a highly porous titanium cup in an acetabular bone defect model. J Orthop Sci 23(4):665–670
Dall’Ava L, Hothi H, Henckel J, Di Laura A, Tirabosco R, Eskelinen A, Skinner J, Hart A (2021) Osseointegration of retrieved 3D-printed, off-the-shelf acetabular implants. Bone Jt Res 10(7):388–400
Toro G, Bothorel H, Saffarini M, Jacquot L, Chouteau J, Rollier JC (2019) Uncemented total hip arthroplasty in octogenarian and nonagenarian patients. Eur J Orthop Surg Traumatol 29(1):103–110
Devine D, Arens D, Burelli S, Bloch HR, Boure L (2012) In vivo evaluation of the osteointegration of new highly-porous trabecular titanium™. J Bone Jt Surg Br 94-b(suppl XXXVII):201
Kuribayashi M, Takahashi KA, Fujioka M, Ueshima K, Inoue S, Kubo T (2010) Reliability and validity of the Japanese orthopaedic association hip score. J Orthop Sci 15(4):452–458
DeLee JG, Charnley J (1976) Radiological demarcation of cemented sockets in total hip replacement. Clin Orthop Relat Res 121(121):20–32
Sugano N, Nishii T, Nakata K, Masuhara K, Takaoka K (1995) Polyethylene sockets and alumina ceramic heads in cemented total hip arthroplasty. A ten-year study. J Bone Jt Surg Br 77(4):548–556
Wegrzyn J, Kaufman KR, Hanssen AD, Lewallen DG (2015) Performance of porous tantalum vs. titanium cup in total hip arthroplasty: randomized trial with minimum 10-year follow-up. J Arthroplast 30(6):1008–1013
Marin E, Fusi S, Pressacco M, Paussa L, Fedrizzi L (2010) Characterization of cellular solids in Ti6Al4V for orthopaedic implant applications: trabecular titanium. J Mech Behav Biomed Mater 3(5):373–381
Perticarini L, Zanon G, Rossi SM, Benazzo FM (2015) Clinical and radiographic outcomes of a trabecular titanium™ acetabular component in hip arthroplasty: results at minimum 5 years follow-up. BMC Musculoskelet Disord 16:375
Chen H, Zhou X, Fujita H, Onozuka M, Kubo KY (2013) Age-related changes in trabecular and cortical bone microstructure. Int J Endocrinol 2013:213234
Yoshimura N, Muraki S, Oka H, Mabuchi A, En-Yo Y, Yoshida M, Saika A, Yoshida H, Suzuki T, Yamamoto S, Ishibashi H, Kawaguchi H, Nakamura K, Akune T (2009) Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study. J Bone Miner Metab 27(5):620–628
Sagomonyants KB, Hakim-Zargar M, Jhaveri A, Aronow MS, Gronowicz G (2011) Porous tantalum stimulates the proliferation and osteogenesis of osteoblasts from elderly female patients. J Orthop Res 29(4):609–616
Tamaki Y, Goto T, Takasago T, Wada K, Hamada D, Sairyo K (2022) Clinical and radiological outcomes of total hip arthroplasty using a highly porous titanium cup or a conventional hydroxyapatite-coated titanium cup: a retrospective study in Japanese patients. J Orthop Sci 27(1):163–168
Zielinski MR, Deckard ER, Meneghini RM (2021) The fate of zone 2 radiolucencies in contemporary highly porous acetabular components: not all designs perform equally. Arthroplast Today 8:96–102
Imai H, Miyawaki J, Kamada T, Maruishi A, Takeba J, Miura H (2019) Radiolucency around highly porous sockets and hydroxyapatite-coated porous sockets in total hip arthroplasty for hip dysplasia. Eur J Orthop Surg Traumatol 29(3):611–618
Miyagawa T, Matsumoto K, Komura S, Akiyama H (2021) Total hip arthroplasty using a three-dimensional porous titanium acetabular cup: an examination of micromotion using subject-specific finite element analysis. BMC Musculoskelet Disord 22(1):308
Oishi K, Yamamoto Y, Harada Y, Inoue R, Sasaki E, Ishibashi Y (2021) Radiographic assessment of radiolucent lines around a highly porous titanium cup (Tritanium) using digital tomosynthesis, after total hip arthroplasty. J Orthop Surg Res 16(1):266
Acknowledgements
We thank Editage (www.editage.com) for editing a draft of this manuscript.
Funding
This study was supported by a Grant-in-Aid for Translational Research, Tokyo Metropolitan Institute of Gerontology, and a scholarship grant from Teijin Pharma Limited.
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All authors have read and approved the final manuscript. TK, FT, and TM conceived and designed the study. TK, SN, KH, and TM analyzed and interpreted the data. TK and TM wrote the paper. TM supervised all the work.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/ or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the medical research ethics committee at our institute.
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Kaneko, T., Nakamura, S., Hayakawa, K. et al. Clinical and radiological outcomes of total hip arthroplasty in octogenarian patients using a three-dimensional porous titanium cup: a retrospective analysis in Japanese patients. Eur J Orthop Surg Traumatol 33, 2361–2367 (2023). https://doi.org/10.1007/s00590-022-03439-0
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DOI: https://doi.org/10.1007/s00590-022-03439-0