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The influence of alternate part-time patching on control of intermittent exotropia: a randomized clinical trial

  • Pediatrics
  • Published:
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Abstract

Purpose

To evaluate the effect of alternate part-time patching on deviation control in patients with intermittent exotropia in comparison to observation.

Methods

In a randomized clinical trial, untreated 3–8-year-old children with intermittent exotropia were randomly divided into patching group who treated with alternate part-time patching and observation group. Deviation control was assessed with 3-point and 6-point scales. Stereoacuity and suppression were evaluated with Titmus and Worth-4-dot tests respectively. All exams were repeated 3 and 6 months after beginning of treatment.

Results

Seventy-six patients (35 in patching and 41 in observation group) with a mean age of 4.99 ± 1.33 years completed the 6-month course of study. Based on 3-point scale, deviation control was significantly better in patching group after 3 and 6 months at near and after 3 months at far (p = 0.011, 0.011, and 0.03, respectively) but non-significant after 6 months at far (p = 0.16). According to 6-point scale, deviation control was also significantly better in patching group after 3 months (p = 0.03 at far, 0.003 at near) and 6 months (p = 0.03 at far, 0.003 at near). Three and 6 months stereoacuity was not significantly different between groups (p = 0.86 for both). However, there was greater stereoacuity changes among patching group in comparison with observation group from baseline to 3 and 6 months (p = 0.006 for both).

Conclusion

Patching seems effective in improving deviation control of 3–8-year-old children with intermittent exotropia in comparison with observation based on two common office control scales.

Trial registration number and date

NCT03700632 (10/9/2018)

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Data availability

All data generated or analyzed during this study are available.

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Authors and Affiliations

  1. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Mohammad Reza Akbari, Mohammad Mehrpour & Arash Mirmohammadsadeghi

Authors
  1. Mohammad Reza Akbari
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  2. Mohammad Mehrpour
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  3. Arash Mirmohammadsadeghi
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Contributions

All the authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by all the authors. The first draft of the manuscript was written by Mohammad Mehrpour, and all the authors commented on previous versions of the manuscript. All the authors read and approved the final manuscript.

Corresponding author

Correspondence to Arash Mirmohammadsadeghi.

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Conflicts of interest

The authors declare that they have no conflict of interest.

Ethics approval

The study was compliant with the principles of the Declaration of Helsinki. The Ethics Committee of Tehran University of Medical Sciences approved the study design.

Consent to participate

Informed consent was obtained from all individual participants included in the study.

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Not applicable.

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Akbari, M.R., Mehrpour, M. & Mirmohammadsadeghi, A. The influence of alternate part-time patching on control of intermittent exotropia: a randomized clinical trial. Graefes Arch Clin Exp Ophthalmol 259, 1625–1633 (2021). https://doi.org/10.1007/s00417-020-05065-0

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  • DOI: https://doi.org/10.1007/s00417-020-05065-0

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