Skip to main content

Advertisement

SpringerLink
Log in

Fat Reduction Using Phosphatidylcholine/Sodium Deoxycholate Injections: Standard of Practice

  • Original Article
  • Published:
Aesthetic Plastic Surgery Aims and scope Submit manuscript

Abstract

The practice of injecting phosphatidylcholine/sodium deoxycholate compounds into subcutaneous fat is growing rapidly. As with any new procedure, a standard of practice should be developed so that practitioners maintain patient safety as the primary goal. Efficacy and predictability of outcome are another priority. As injection lipolysis, also known as “lipodissolve,” becomes more accepted, many standards are being set, such as indications, contraindications, acceptable postinjection sequelae, best regions to treat, regions to avoid, and expected outcomes. This article establishes a basis of practice for the practitioner interested in adding this procedure to his or her repertoire.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12

Similar content being viewed by others

References

  1. Duncan DI, Chubaty R (2006) Clinical safety data and standards of practice for injection lipolysis: A retrospective study. Aesth Surg J 26:575–585

    Article  CAS  Google Scholar 

  2. Palmer M, Curran J, Bowler P (2006) Clinical experience and safety using phosphatidylcholine injections for the localized reduction of subcutaneous fat: A multicentre, retrospective UK study. J Cosmetic Derm 5:218–226

    Article  Google Scholar 

  3. Rotunda A (2006) Overview of Mesotherapy and Injection Lipolysis. International Mesolipotherapy instructional course. Las Vegas

  4. LeCoz J (2004) Traite de Mesoterapie. Masson, Paris, pp 7–9

    Google Scholar 

  5. Duncan DI, Hasengschwandtner F (2005) Lipodissolve for subcutaneous fat reduction and skin retraction. Aesth Surg J 25:530–543

    Article  CAS  Google Scholar 

  6. Rohrich RJ (2005) Mesotherapy: What is it? Does it work? Plast Reconstr Surg 115:1425

    Article  PubMed  CAS  Google Scholar 

  7. The American Society of Aesthetic Plastic Surgery (2004) Fat-Melting Fad: Too Good to Be True? (Internet) American Society for Aesthetic Plastic Surgery: New York. Available at http://www.surgery.org./press/news-release

  8. The American Society of Aesthetic Plastic Surgery (2007) Position Statement on Injection Lipolysis, New York, NY

  9. Bryant R (2004) Controversial mesotherapy: Could it be the next Botox? Dermatology Times, pp 1–2

  10. Rittes PG (2001) The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 27:391–392

    Article  PubMed  CAS  Google Scholar 

  11. Rittes PG (2003) The use of phosphatidylcholine for correction of localized fat deposits. Aesth Surg J 27:315–318

    Article  Google Scholar 

  12. Hexsel D, Serra M, Mazzuco R et al (2003) Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2:511–518

    PubMed  Google Scholar 

  13. Hasengschwandtner F. Lipodissolve Injections for Effective Reduction of Localized Fat as a Nonsurgical Option to Minor Lipoplasty. 2003–2004 Clinical Study. Network Lipodissolve members report, Bad Leonfelden

  14. Duncan DI (2006) The Evolution of Mesotherapy. ASPS Breast and Body Contouring Symposium, Santa Fe

    Google Scholar 

  15. Hasengschwandtner F (2006) Injection lipolysis for effective reduction of localized fat in the place of minor lipoplasty. Aesth Surg J 26:125–130

    Article  CAS  Google Scholar 

  16. Popp G, Hernuss P et al Lipodissolve Injections in Follow-up for Correctional Treatment After Lipoplasty. World Congress on Liposuction Surgery, 1–3 October, St. Louis, MO

  17. Ablon G, Rotunda AM (2004) Treatment of lower eyelid fat pads using phosphatidylcholine: Clinical trial and review. Dermatol Surg 30:422–427

    Article  PubMed  Google Scholar 

  18. Rullan P, Hexsel D (2005) Phosphatidylcholine Injections for Lipolysis of Neck and Jowls: 50-Case Presentation. American Society for Dermatologic Surgery–American College of Mohs Micrographic Surgery and Cutaneous Oncology combined annual meeting

  19. Rose PT, Morgan M (2005) Histological changes associated with mesotherapy for fat dissolution. J Cosmet Laser Ther 7:17–19

    Article  PubMed  Google Scholar 

  20. Duncan DI (2005) Precision and Finesse in Injection Lipolysis. Congress of Network Lipodissolve, Paris

    Google Scholar 

  21. Rittes PG (2007) Injection Lipolysis: Technique and Results. International Mesolipotherapy Society instructional course, Nashville

    Google Scholar 

  22. Salas P (2006) Injection Lipolysis With Phosphatidylcholine. ASAPS annual meeting, Orlando, FL

    Google Scholar 

  23. Walsh N (2004) Some would halt lipolysis tx pending safety data. Skin Allergy News 35:26

    Google Scholar 

  24. Fat-Melting Fad (2004) Too Good to Be True? ASAPS news release, pp 1–2

  25. Rosen D (2007) PC/DC and Its Contemplated Use. Personal communication

  26. Bush AM (2007) State decides to regulate substances used in weight loss. The Capital Journal. Available at http://www.cjonline.com

  27. Veroffentlichungen (2006) Available at http://www.//netzwerk-lipolyse.de

  28. Rittes PG (2006) Why ANVISA Banned the Use of Lipostabil for Injection Lipolysis in Brazil. Personal communication. International Mesolipotherapy Society instructional course, Las Vegas

    Google Scholar 

  29. Hexsel D et al (2005) Cosmetic use of injectable phosphatidylcholine on the face. Otolarngol Clin North Am 38:1119–1129

    Article  Google Scholar 

  30. Rotunda AM, Kolodney MS (2006) Mesotherapy and phosphatidylcholine injections: historical clarification and review. Derm Surg 32(4):465–480

    Article  CAS  Google Scholar 

  31. Meissner C (2005) Complications With Lipodissolve. First International Convention for Lipodissolve, Salzburg, Austria

    Google Scholar 

  32. Duncan DI (2006) Precision in Technique: Injection Lipolysis. IMCAS, Paris

    Google Scholar 

  33. Rotunda AM, Ablon G, Kolodney MS (2005) Lipomas treated with subcutaneous injections of sodium deoxycholate. J Am Acad Dermatol 53:973–978

    Article  PubMed  Google Scholar 

  34. Duncan DI (2007) Noninvasive Correction of Postsurgical Deformities. ASAPS annual meeting, New York

    Google Scholar 

  35. Hasengschwandtner F (2005) Injection Lipolysis Basics. First International Convention for Lipodissolve, Salzburg, Austria

    Google Scholar 

  36. Duncan DI (2007) Dispersion Studies. Instructional course, Global Network Lipolysis

  37. Laddy S (2007) MasterPharm conference call

  38. Duncan DI (2006) Technique of Injection Lipolysis. QMP annual meeting, Chicago

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. 1701 East Prospect Road, Fort Collins, CO, 80524, USA

    Diane Irvine Duncan

  2. 100, Harley Street, London, W1G 7JA, UK

    Mark Palmer

Authors
  1. Diane Irvine Duncan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mark Palmer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Diane Irvine Duncan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Duncan, D.I., Palmer, M. Fat Reduction Using Phosphatidylcholine/Sodium Deoxycholate Injections: Standard of Practice. Aesth Plast Surg 32, 858–872 (2008). https://doi.org/10.1007/s00266-008-9188-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00266-008-9188-9

Keywords

Search

Navigation