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Magnetic resonance imaging evaluation of osteoid osteoma: utility of the dark rim sign

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Abstract

Background

While typical patterns of osteoid osteoma have been described on CT, MRI findings can overlap among different diseases, and atypical patterns exist. In this study, we assessed the presence of a novel dark rim sign and its utility in the MRI diagnosis of osteoid osteoma.

Objective

The purpose of this retrospective study was to assess the utility of the dark rim sign seen on MRI in children with osteoid osteoma.

Materials and methods

MRI studies from 36 pediatric patients with osteoid osteoma and a control group of patients with either osteomyelitis or stress fracture were analyzed and then compared for the presence of the dark rim sign. Patients from the osteoid osteoma group were further divided based on nidus location and evaluated for the presence of the dark rim sign.

Results

The relationship between the dark rim sign and osteoid osteoma was statistically significant (P<0.001). A dark rim sign was identified in 25 of the 36 patients with osteoid osteoma. None of the control patients had a dark rim sign. The dark rim sign had 69.4% sensitivity, 100% specificity, 100% positive predictive value and 72.5% negative predictive value for detecting osteoid osteoma. The relationship between dark rim sign and nidus location was statistically significant (P<0.001) such that endosteal and medullary osteoid osteomas were more likely to have a dark rim sign than intracortical osteoid osteomas.

Conclusion

When the nidus of an osteoid osteoma is in an endosteal or medullary location, the dark rim sign may aid in the diagnosis.

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Authors and Affiliations

  1. University of Central Florida College of Medicine, Orlando, FL, USA

    Jerry French

  2. Department of Radiology, Nemours Children’s Hospital, Orlando, FL, USA

    Monica Epelman, Craig M. Johnson & Zachary S. Stinson

  3. Department of Radiology, Columbia University Medical Center, New York, NY, USA

    Diego Jaramillo

  4. Department of Radiology, Cincinnati Children’s Hospital Medical Center, 3333 Burnett Ave., Cincinnati, OH, 45229, USA

    Arthur B. Meyers

Authors
  1. Jerry French
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  2. Monica Epelman
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  3. Diego Jaramillo
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  4. Craig M. Johnson
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  5. Zachary S. Stinson
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  6. Arthur B. Meyers
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Correspondence to Arthur B. Meyers.

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Dr. Meyers is an author/editor for Elsevier/Amirsys receiving royalties.

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Appendix

Appendix

Appendix Table 1 Demographic and lesion information for patients with osteoid osteoma included in this study
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Appendix Table 2 Demographic and lesion information for control patients with osteomyelitis or stress fracture included in this study
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French, J., Epelman, M., Jaramillo, D. et al. Magnetic resonance imaging evaluation of osteoid osteoma: utility of the dark rim sign. Pediatr Radiol 50, 1742–1750 (2020). https://doi.org/10.1007/s00247-020-04780-4

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  • DOI: https://doi.org/10.1007/s00247-020-04780-4

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