Skip to main content
Log in

Percutaneous nephrolithotomy in patients with incidental encountered purulent urine at initial puncture

  • Research
  • Published:
Urolithiasis Aims and scope Submit manuscript

Abstract

We are reporting the 39 patients’ outcomes who underwent percutaneous nephrolithotomy and purulent urine encountered at the initial steps of surgery. Of 873 patients who underwent PCNL, 48 had purulent fluid during the initial puncture. After excluding those at risk for infection, we studied 39 patients’ preoperative and postoperative variables-including postoperative day (POD) 1, 3, 5 fevers. In group 1, 21 patients had a nephrostomy tube placed, and PCNL was postponed. In group 2, 18 patients had successful stone removal in the first session. All surgeries were successful, with no septic events during follow-up. No significant differences in preoperative variables were found. 14% and 22% of patients in groups 1 and 2 had infected fluid (p = 0.470). Four patients in group 1 (19%) and seven patients in group 2 (38.9%) had a high fever (≥ 38 C) on POD1 (p = 0.171), and 1 (5%) in group 1 and 3 (17%) in group 2 had high fever on POD 3 (p = 0.22). No patients remained with high fever on POD5. Mild sepsis was diagnosed in 9.5% of group 1 and 16% of group 2 (p = 0.820), and hospitalization time differed significantly (p < 0.001). Stone size and operation time were correlated with postoperative fever, and prolonged hospital stays were associated with positive blood cultures and postponed procedures. PCNL with proper technique and antibiotics can lead to quicker recovery and reduced hospitalization time in selected patients with pus in their pelvicalyceal system.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. EAU-Guidelines-on-Urolithiasis-2023.pdf. https://d56bochluxqnz.cloudfront.net/documents/full-guideline/EAU-Guidelines-on-Urolithiasis-2023.pdf

  2. de la Rosette J, Assimos D, Desai M, Gutierrez J, Lingeman J, Scarpa R et al (2011) The clinical research office of the endourological society percutaneous nephrolithotomy global study: indications, complications, and outcomes in 5803 patients. J Endourol 25(1):11–17

    Article  PubMed  Google Scholar 

  3. Rivera M, Viers B, Cockerill P, Agarwal D, Mehta R, Krambeck A (2016) Pre—and postoperative predictors of infection-related complications in patients undergoing percutaneous nephrolithotomy. J Endourol 30(9):982–986

    Article  PubMed  Google Scholar 

  4. Bapir R, Bhatti KH, Eliwa A, García-Perdomo HA, Gherabi N, Hennessey D et al (2022) Infectious complications of endourological treatment of kidney stones: a meta-analysis of randomized clinical trials. Arch Ital Urol Androl Organo Uff Soc Ital Ecogr Urol E Nefrol 94(1):97–106

    Article  Google Scholar 

  5. Liang X, Huang J, Xing M, He L, Zhu X, Weng Y et al (2019) Risk factors and outcomes of urosepsis in patients with calculous pyonephrosis receiving surgical intervention: a single-center retrospective study. BMC Anesthesiol 19(1):61

    Article  PubMed  PubMed Central  Google Scholar 

  6. Lightner DJ, Wymer K, Sanchez J, Kavoussi L (2020) Best practice statement on urologic procedures and antimicrobial prophylaxis. J Urol 203(2):351–356

    Article  PubMed  Google Scholar 

  7. Vorrakitpokatorn P, Permtongchuchai K, Raksamani EO, Phettongkam A (2006) Perioperative complications and risk factors of percutaneous nephrolithotomy. J Med Assoc Thail Chotmaihet Thangphaet 89(6):826–833

    Google Scholar 

  8. Rao PN, Dube DA, Weightman NC, Oppenheim BA, Morris J (1991) Prediction of septicemia following endourological manipulation for stones in the upper urinary tract. J Urol 146(4):955–960

    Article  CAS  PubMed  Google Scholar 

  9. Zeng G, Zhong W, Pearle M, Choong S, Chew B, Skolarikos A et al (2022) European association of urology section of urolithiasis and international alliance of urolithiasis joint consensus on percutaneous nephrolithotomy. Eur Urol Focus 8(2):588–597

    Article  PubMed  Google Scholar 

  10. Doğan HS, Sahin A, Cetinkaya Y, Akdoğan B, Ozden E, Kendi S (2002) Antibiotic prophylaxis in percutaneous nephrolithotomy: prospective study in 81 patients. J Endourol 16(9):649–653

    Article  PubMed  Google Scholar 

  11. Draga ROP, Kok ET, Sorel MR, Bosch RJLH, Lock TMTW (2009) percutaneous nephrolithotomy: factors associated with fever after the first postoperative day and systemic inflammatory response syndrome. J Endourol 23(6):921–927

    Article  PubMed  Google Scholar 

  12. Aron M, Goel R, Gupta NP, Seth A (2005) Incidental detection of purulent fluid in kidney at percutaneous nephrolithotomy for branched renal calculi. J Endourol 19(2):136–139

    Article  PubMed  Google Scholar 

  13. Etemadian M, Haghighi R, Madineay A, Tizeno A, Fereshtehnejad SM (2008) Delayed versus same-day percutaneous nephrolithotomy in patients with aspirated cloudy urine. Urol J 5(1):28–33

    PubMed  Google Scholar 

  14. Guo S, Zhang X, Li F, Sun C, Zhang Y, Cao X (2022) One-stage tubeless percutaneous nephrolithotomy for asymptomatic calculous pyonephrosis. BMC Urol 7(22):29

    Article  Google Scholar 

  15. Hosseini MM, Basiri A, Moghaddam SMH (2007) Percutaneous nephrolithotomy of patients with staghorn stone and incidental purulent fluid suggestive of infection. J Endourol 21(12):1429–1432

    Article  CAS  PubMed  Google Scholar 

  16. Huang J, Song L, Xie D, Li M, Deng X, Hu M et al (2016) A randomized study of minimally invasive percutaneous nephrolithotomy (MPCNL) with the aid of a patented suctioning sheath in the treatment of renal calculus complicated by pyonephrosis by one surgery. BMC Urol 16(1):71

    Article  PubMed  PubMed Central  Google Scholar 

  17. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M et al (2016) The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315(8):801–810

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Mariappan P, Loong CW (2004) Midstream urine culture and sensitivity test is a poor predictor of infected urine proximal to the obstructing ureteral stone or infected stones: a prospective clinical study. J Urol 171(6 Pt 1):2142–2145

    Article  PubMed  Google Scholar 

  19. Kreydin EI, Eisner BH (2013) Risk factors for sepsis after percutaneous renal stone surgery. Nat Rev Urol 10(10):598–605

    Article  PubMed  Google Scholar 

  20. Margel D, Ehrlich Y, Brown N, Lask D, Livne PM, Lifshitz DA (2006) Clinical implication of routine stone culture in percutaneous nephrolithotomy–a prospective study. Urology 67(1):26–29

    Article  CAS  PubMed  Google Scholar 

  21. Gonen M, Turan H, Ozturk B, Ozkardes H (2008) Factors affecting fever following percutaneous nephrolithotomy: a prospective clinical study. J Endourol 22(9):2135–2138

    Article  PubMed  Google Scholar 

  22. Gutierrez J, Smith A, Geavlete P, Shah H, Kural AR, de Sio M et al (2013) Urinary tract infections and post-operative fever in percutaneous nephrolithotomy. World J Urol 31(5):1135–1140

    Article  PubMed  Google Scholar 

  23. Chen L, Xu QQ, Li JX, Xiong LL, Wang XF, Huang XB (2008) Systemic inflammatory response syndrome after percutaneous nephrolithotomy: an assessment of risk factors. Int J Urol Off J Jpn Urol Assoc 15(12):1025–1028

    Google Scholar 

  24. Wang Y, Jiang F, Wang Y, Hou Y, Zhang H, Chen Q et al (2012) Post-percutaneous nephrolithotomy septic shock and severe hemorrhage: a study of risk factors. Urol Int 88(3):307–310

    Article  CAS  PubMed  Google Scholar 

  25. Seitz C, Desai M, Häcker A, Hakenberg OW, Liatsikos E, Nagele U et al (2012) Incidence, prevention, and management of complications following percutaneous nephrolitholapaxy. Eur Urol 61(1):146–158

    Article  PubMed  Google Scholar 

  26. Zhong W, Zeng G, Wu K, Li X, Chen W, Yang H (2008) Does a smaller tract in percutaneous nephrolithotomy contribute to high renal pelvic pressure and postoperative fever? J Endourol 22(9):2147–2151

    Article  PubMed  Google Scholar 

  27. Troxel SA, Low RK (2002) Renal intrapelvic pressure during percutaneous nephrolithotomy and its correlation with the development of postoperative fever. J Urol 168(4 Pt 1):1348–1351

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

Dr.TS and Dr.EY Wrote the main manuscript. Dr. IS and Dr. MA helped with tables preparation and documents Dr. EY helped with the review and writing.

Corresponding author

Correspondence to Timucin Sipal.

Ethics declarations

Conflict of interests

The authors declare no conflict of interests.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sipal, T., Senocak, I., Ataman, M. et al. Percutaneous nephrolithotomy in patients with incidental encountered purulent urine at initial puncture. Urolithiasis 51, 107 (2023). https://doi.org/10.1007/s00240-023-01481-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00240-023-01481-z

Keywords

Navigation