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Kutanes Rosai-Dorfman-Syndrom

Erfolgreiche Therapie mit intraläsional applizierten Steroiden

Cutaneous Rosai-Dorfman syndrome

Succesful therapy with intrralesional corticosteroids

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An Erratum to this article was published on 06 September 2014

Zusammenfassung

Hintergrund

Das kutane Rosai-Dorfman-Syndrom ist eine seltene Nicht-Langerhans-Zell-Histiozytose, die durch eine dermale Infiltration von Histiozyten sowie einem Begleitinfiltrat aus Lymphozyten, Plasmazellen und Granulozyten charakterisiert ist. Aufgrund ihrer Seltenheit existiert kein standardisiertes Therapieschema.

Fallbericht

Wir berichten über den Fall eines 27-jährigen Patienten, der auf intraläsional injiziertes Triamcinolon hervorragend ansprach. Therapieversuche mittels Exzision sowie Laserbehandlungen wie auch eine systemische Behandlung mit Methotrexat und Prednisolon waren zuvor frustran verlaufen.

Abstract

Background

Cutaneous Rosai-Dorfman disease is a rare disorder belonging to the spectrum of non-Langerhans cell histiocytoses. It is characterized by dermal and subcutaneous infiltrates of histiocytes as well as accompanying lymphocytes, plasma cells and granulocytes. Because it is so rare, standard therapies have not been established.

Case report

A 27-year-old man showed an excellent response to intralesional corticosteroids after unsuccessful prior treatment with methotrexate, systemic steroids and surgery as well as laser therapy.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. S. Vandersee, H.-J. Röwert-Huber, S. Wöhner, C. Loddenkemper, M. Beyer und D. Humme geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren. Alle Patienten, die über Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben. Im Falle von nicht mündigen Patienten liegt die Einwilligung eines Erziehungsberechtigten oder des gesetzlich bestellten Betreuers vor.

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Authors and Affiliations

  1. Hauttumorcentrum der Charité, Klinik für Dermatologie, Venerologie und Allergologie, Charité Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland

    S. Vandersee, H.-J. Röwert-Huber, M. Beyer & D. Humme

  2. Onkologische Schwerpunktpraxis Tiergarten, Berlin, Deutschland

    S. Wöhner

  3. PathoTres Gemeinschaftspraxis für Pathologie, Berlin, Deutschland

    C. Loddenkemper

Authors
  1. S. Vandersee
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  2. H.-J. Röwert-Huber
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  3. S. Wöhner
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  4. C. Loddenkemper
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  5. M. Beyer
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  6. D. Humme
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Corresponding author

Correspondence to S. Vandersee.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s00105-014-2869-1.

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Vandersee, S., Röwert-Huber, HJ., Wöhner, S. et al. Kutanes Rosai-Dorfman-Syndrom. Hautarzt 65, 725–727 (2014). https://doi.org/10.1007/s00105-014-2797-0

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  • DOI: https://doi.org/10.1007/s00105-014-2797-0

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