Abstract
The treatment of 2,6-difluorobenzoyl chloride with trimethylsilyl isocyanate gave 2,6-difluorobenzoyl isocyanate. This product reacts with polyfluoroaromatic amines to give the corresponding N-(2,6-difluorobenzoyl)-N′-(polyfluoroaryl)urea, which hold potential as inhibitors for the biosynthesis of insect chitin.
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Additional information
Institute of Chemistry, Bashkir Science Center, Urals Branch, Russian Academy of Sciences, 450054 Ufa. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 630090 Novosibirsk. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 2, pp. 468–470, February, 1992.
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Odinokov, V.N., Kukovinets, O.S., Lozhkina, E.A. et al. New approach to the synthesis of 2,6-difluorobenzoyl isocyanate and its use in the preparation of N-(2,6-difluorobenzoyl)-N′-(polyfluoroaryl)ureas. Russ Chem Bull 41, 374–376 (1992). https://doi.org/10.1007/BF00869540
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DOI: https://doi.org/10.1007/BF00869540