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Acyclovir in the management of herpes virus infections in immunosuppressed children

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Summary

Six children, aged from 5 to 15 years who developed herpes virus infections while on chemotherapy for malignant disease were treated with systemic acyclovir (Acycloguanasine). Clinical response was evident in all patients with no adverse effects or toxicity. The mechanism of action of the drug, mode of administration and possible side effects are discussed and comparisons drawn with the already published data on its use in humans.

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Authors and Affiliations

  1. Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin 12

    Anne O'Meara

  2. Department of Medical Microbiology, University College, Belfield, Dublin 4

    Irene B. Hillary

Authors
  1. Anne O'Meara
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  2. Irene B. Hillary
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O'Meara, A., Hillary, I.B. Acyclovir in the management of herpes virus infections in immunosuppressed children. I.J.M.S. 150, 73–77 (1981). https://doi.org/10.1007/BF02938203

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  • DOI: https://doi.org/10.1007/BF02938203

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