Abstract
Following Wei's suggestion that nerve stimulation and conduction properties are due to dipole layers at the two membrane surfaces (Wei, 1969), we have done steady-state electro-diffusion calculations in the constant field approximation for a simple double-dipole-layer model. We are thereby able to quantitatively fit the recent potassium iso-osmotic rectification curves of Gilbert and Ehrenstein for the squid giant axon membrane. For the squid axon membrane in a natural ion environment, only the outside dipole layer is present in the fit to the data.
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Arndt, R.A., Bond, J.D. & David Roper, L. A fit to nerve membrane rectification curves with a double-dipole-layer membrane model. Bulletin of Mathematical Biophysics 34, 151–172 (1972). https://doi.org/10.1007/BF02476514
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DOI: https://doi.org/10.1007/BF02476514