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Cannflavin A and B, prenylated flavones fromCannabis sativa L.

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Summary

Two novel prenylat flavones, termed Cannflavin A and B, were isolated from the cannabinoid free ethanolic extract ofCannabis sativa L. Both compounds inhibited prostaglandin E2 production by human rheumatoid synovial cells in culture.

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Author notes

  1. M. L. Barrett

    Present address: Dept. of Pharmacology, Institute of Basic Medical Sciences, Royal College of Surgeons of England, Lincoln's Inn Fields, WC2A 3PN, London

  2. A. M. Scutt

    Present address: Dept. of Oral and Maxillofacial Surgery, Institute of Dental Surgery, Grays Inn Road, WC1X 8LD, London

Authors and Affiliations

  1. Department of Pharmacognosy, The School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, England

    M. L. Barrett, A. M. Scutt & F. J. Evans

Authors
  1. M. L. Barrett
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  2. A. M. Scutt
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  3. F. J. Evans
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Additional information

This communication is dedicated to the memory of the late Professor J. W. Fairbairn and the late Dr. J. T. Pickens. We are grateful to the Medical Research Council for a project grant and to Ms J. Elliot of King's College London for NMR spectra.

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Barrett, M.L., Scutt, A.M. & Evans, F.J. Cannflavin A and B, prenylated flavones fromCannabis sativa L.. Experientia 42, 452–453 (1986). https://doi.org/10.1007/BF02118655

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