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Effect of estradiol on spontaneous single unit activity in the arcuate region of the rat hypothalamus at various stages of the estrous cycle

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Microiontophoretic injection of estradiol into the arcuate region of the hypothalamus in the overwhelming majority of experiments enhanced single unit activity. The response was more marked in diestrus-1 and diestrus-2 than in proestrus. It is suggested that changes in the predominant response of arcuate neurons to injection of estradiol in the course of the sex cycle are determined by the level of endogenous estrogens and pituitary gonadotropic hormones in the peripheral blood.

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Authors
  1. V. N. Babichev
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  2. V. Ya. Ignatkov
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Babichev, V.N., Ignatkov, V.Y. Effect of estradiol on spontaneous single unit activity in the arcuate region of the rat hypothalamus at various stages of the estrous cycle. Bull Exp Biol Med 83, 239–242 (1977). https://doi.org/10.1007/BF00799434

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  • DOI: https://doi.org/10.1007/BF00799434

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