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Synthesis of 5-vinylindole by simultaneous dehydrogenation and decarboxylation of 5-ethyl-indole-2-carboxylic acid and its ethyl ester

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A new method is proposed for the synthesis of 5-vinylindole by simultaneous catalytic dehydrogenation and decarboxylation of 5-ethylindole-2-carboxylic acid and its ethyl ester, making it possible to more than double the yield of the previously described method.

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Literature Cited

  1. N. N. Suvorov, N. E. Starostenko, and F. N. Zeiberlikh, USSR Inventor's Certificate No. 777,026; Byull. Izobret., No. 41, 87 (1980).

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  3. N. N. Suvorov, N. E. Starostenko, and F. N. Zeiberlikh, Zh. Org. Khim., 16, 2609 (1980).

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Authors and Affiliations

  1. D. I. Mendeleev Moscow Chemical Engineering Institute, 125047, Moscow

    N. E. Starostenko, Fung Tien Dat, I. A. Serova, A. V. Kamenetskii & N. N. Suvorov

Authors
  1. N. E. Starostenko
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  2. Fung Tien Dat
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  3. I. A. Serova
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  4. A. V. Kamenetskii
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  5. N. N. Suvorov
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 638–641, May, 1991.

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Starostenko, N.E., Dat, F.T., Serova, I.A. et al. Synthesis of 5-vinylindole by simultaneous dehydrogenation and decarboxylation of 5-ethyl-indole-2-carboxylic acid and its ethyl ester. Chem Heterocycl Compd 27, 508–511 (1991). https://doi.org/10.1007/BF00473995

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  • DOI: https://doi.org/10.1007/BF00473995

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