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Comparison of human fibroblast and leukocyte interferon in the treatment of severe laryngeal papillomatosis in children

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Abstract

The efficiency of human fibroblast interferon (IFN-β) and human leukocyte interferon (IFN-α) was evaluated in two children with recurrent laryngeal papillomatosis. Both children failed to respond to fibroblast interferon, however the laryngeal papillomatosis disappeared when leukocyte interferon was applied. Possible explanations for these findings are discussed.

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Author information

Authors and Affiliations

  1. Kinderklinik B der Universität, Moorenstr. 5, D-4000, Düsseldorf, Federal Republic of Germany

    U. Göbel, V. Wahn & H. Jürgens

  2. Hals-Nasen-Ohren-Klinik der Universität Düsseldorf, Federal Republic of Germany

    W. Arnold

  3. Kinderklinik der Universität Tübingen, Federal Republic of Germany

    J. Treuner

  4. Central Public Health Laboratory, Helsinki, Finland

    K. Cantell

Authors
  1. U. Göbel
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  2. W. Arnold
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  3. V. Wahn
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  4. J. Treuner
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  5. H. Jürgens
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  6. K. Cantell
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Göbel, U., Arnold, W., Wahn, V. et al. Comparison of human fibroblast and leukocyte interferon in the treatment of severe laryngeal papillomatosis in children. Eur J Pediatr 137, 175–176 (1981). https://doi.org/10.1007/BF00441312

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  • DOI: https://doi.org/10.1007/BF00441312

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