Summary
The purpose of this report is to present two cases of alobar holoprosencephaly and to review reports from the literature dealing especially with angiographic features of this malformation. — From the features of main cerebral arteries in the present cases, alobar holoprosencephaly may be divided into two types: the azygos artery type which has an unpaired anterior cerebral artery with bilateral middle cerebral arteries, and the undifferentiated artery type with a single undulated main trunk supplying the whole cerebrum. These two types represent the different stages of the malformation in embryonal life.
Résumé
Les auteurs présentent deux cas de holoprosencéphalie alobaire et font une revue de la littérature traitant plus spécialement des signes angiographiques de cette malformation. Les signes angiographiques des deux cas présentés permettent de diviser l'holoprosencéphalie alobaire en deux types: le type comprenant une artère azygos avec artères cérébrale antérieure impaire et cérébrale moyenne bilatérale et le type non différencie comprenant un seul trone principal ondulé alimentant tout le cerveau. Ces deux variétés représentent les différentes étapes de la malformation au cours de la vie embryonnaire.
Zusammenfassung
Es werden 2 Fälle einer alobären Holoprosencephalographie beschrieben und mit den Befunden der Literatur, speziell mit den angiographischen Befunden, verglichen. Dabei kann eine Unterteilung in 2 Gruppen durchgeführt werden. Bei der einen Gruppe handelt es sich um eine unpaare A. cerebri anterior mit einer doppelseitigen A. corebri media. Bei dem undifferenzierten Gefäßtyp (Gruppe 2) liegt lediglich ein einziger Gefäßstrang vor, der das gesamte Gehirn versorgt.
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Maki, Y., Kumagai, K. Angiographic features of alobar holoprosencephaly. Neuroradiology 6, 270–276 (1974). https://doi.org/10.1007/BF00345787
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DOI: https://doi.org/10.1007/BF00345787