Summary
Kittens were reared wearing masks that contained strong cylindrical lenses, which allowed them to see only contours of one orientation. Selective exposure was alternated between the two eyes on successive days, while each time the other eye was covered by the mask. The total duration of exposure was different in the two eyes, amounting to 50 h for one eye and at least 100 h for the other. This resulted in asymmetric distributions of ocular dominance: neurones preferring precisely the experienced orientation favoured the eye with longer exposure, whereas neurones preferring oblique orientations adjacent to the experienced one surprisingly were dominated by the eye with shorter exposure. Thus neurones originally belonging to this group and dominated by the longer exposed eye must have tuned their orientation preference to the experienced orientation as a result of the longer exposure. Such instructive changes seem to be limited by the original response borders of the cortical neurones, as predicted by Hebb's rules for synaptic plasticity.
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References
Barlow HB (1981) Critical limiting factors in the design of the eye and visual cortex. Proc R Soc Lond [Biol] 212: 1–34
Blakemore C, Cooper GF (1970) Development of the brain depends on the visual environment. Nature 228: 477–478
Blasdel GG, Mitchell DE, Muir DW, Pettigrew JD (1977) A physiological and behavioural study in cats of the effects of early visual experience with contours of a single orientation. J Physiol (Lond) 265: 615–636
Freeman RD, Pettigrew JD (1973) Alteration of visual cortex from environmental asymmetries. Nature 246: 359–360
Hebb DO (1949) The organization of behaviour. Wiley, New York
Hirsch HVB, Spinelli DN (1970) Visual experience modifies distribution of horizontally and vertically oriented receptive fields in cats. Science 168: 869–871
Hubel DH, Wiesel TN (1962) Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. J Physiol (Lond) 160: 106–154
Hubel DH, Wiesel TN (1965) Binocular interaction in striate cortex of kittens reared with artificial squint. J Neurophysiol 28: 1041–1059
Rauschecker JP (1979) Orientation-dependent changes in response properties of neurons in the kitten's visual cortex. In: Freeman RD (ed) Developmental neurobiology of vision. Plenum Press, New York, pp 121–133
Rauschecker JP, Singer W (1979) Changes in the circuitry of the kitten visual cortex are gated by postsynaptic activity. Nature 280: 58–60
Rauschecker JP, Singer W (1981) The effects of early visual experience on the cat's visual cortex and their possible explanation by Hebb synapses. J Physiol (Lond) 310: 215–239
Rauschecker JP, Singer W (1982) Binocular deprivation can erase the effects of preceding monocular or binocular vision in kitten cortex. Dev Brain Res 4: 495–498
Rauschecker JP, Singer W, von Grünau MW (1981) Effects of monocular stroboscopic experience on the kitten's visual cortex. In: Szentágothai J, Hámori J, Palkovits M (eds) Advances in Physiological Sciences, vol 2. Regulatory Functions of the CNS. Subsystems, pp 31–39
Stryker MP, Sherk H, Leventhal AG, Hirsch HVB (1978) Physiological consequences for the cat's visual cortex of effectively restricting early visual experience with oriented contours. J Neurophysiol 41: 896–909
Tretter F, Cynader M, Singer W (1975) Modification of direction selectivity of neurons in the visual cortex of kittens. Brain Res 84: 143–149
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Supported by the Deutsche Forschungsgemeinschaft, SFB 50 (Kybernetik)
A part of this study was done at the Max-Planck-Institute for Psychiatry, Dept. of Neurophysiology, D-8000 Munich, Federal Republic of Germany
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Rauschecker, J.P. Instructive changes in the kitten's visual cortex and their limitation. Exp Brain Res 48, 301–305 (1982). https://doi.org/10.1007/BF00237227
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DOI: https://doi.org/10.1007/BF00237227