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Bioinformatics Databases and Tools Available for the Development of Antiviral Drugs

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Advances in Antiviral Research

Abstract

Viruses are responsible for spreading diseases and severe threats to humankind. Emerging viruses and their enigmatic genomic mutations are a serious concern. Lack of precise elucidation and availability of insufficient data is the main barrier to overcoming virus pandemics and epidemics. To tackle the viruses and their emerging variants, the combination of virology and knowledge of bioinformatics leads to light for healthy beings. Viroinformatics is the umbrella term that covers both virology and bioinformatics-based applications. It comprises web servers, tools, and databases flooded with information related to viruses. Resources reported in the chapter include information about coronaviruses, flaviviruses, alphaviruses, influenza viruses, and human immunodeficiency virus (HIV). The chapter also includes the applications of databases and web servers specific to viruses to contribute towards effective vaccines and drug development.

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Acknowledgments

The authors duly acknowledge the financial support from the Science and Engineering Research Board (SERB), Department of Science and Technology (DST), and Government of India under the scheme Intensification of Research in High Priority Area (IRHPA) (Project no. IPA/2020/000054). The authors also thank the DST-sponsored Translation and Structural Bioinformatics Center at Department of Biosciences and Bioengineering (BSBE), IIT Roorkee (reference number BT/PR40141/BTIS/137/16/2021).

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Correspondence to Shailly Tomar or Jitin Singla .

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© 2024 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Singh, A., Dhaka, P., Kumar, P., Tomar, S., Singla, J. (2024). Bioinformatics Databases and Tools Available for the Development of Antiviral Drugs. In: Kumar, N., Malik, Y.S., Tomar, S., Ezzikouri, S. (eds) Advances in Antiviral Research. Livestock Diseases and Management. Springer, Singapore. https://doi.org/10.1007/978-981-99-9195-2_2

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