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Introduction to Online Nucleic Acid Databases for EV Research

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Extracellular Vesicles

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Abstract

Extracellular vesicles (EVs), a type of lipid membrane-coated vesicles, contain proteins, DNA, RNAs, and lipids and are categorized into three main subclasses: exosomes, microvesicles, and apoptotic bodies. These EVs participate in cell-cell communication and regulate the extracellular environment. With the expansion of studies on the functions and regulations of EVs, many web-accessible databases focusing on the molecular cargoes of EVs have emerged. In this chapter, we summarize currently available online nucleic acid databases for EV research, including exoCarta, miRandola 2017, exoRBase 2.0, EVAtlas, Vesiclepedia 2019, exRNA Atlas, deepBase v3.0, and EVLncRNAs v2.0. Furthermore, we provide a detailed discussion of information on EV statistics, features, usage, and expression among these databases. These databases may facilitate the discovery of regulatory mechanisms, biological functions, and clinical biomarkers associated with EVs.

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Authors and Affiliations

  1. Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai, China

    Jia Hu & Shenglin Huang

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  1. Jia Hu
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  2. Shenglin Huang
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Correspondence to Shenglin Huang .

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Editors and Affiliations

  1. Zhujiang Hospital, Southern Medical University, Guangzhou, China

    Qian Wang

  2. Nanfang Hospital, Southern Medical University, Guangzhou, China

    Lei Zheng

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Hu, J., Huang, S. (2024). Introduction to Online Nucleic Acid Databases for EV Research. In: Wang, Q., Zheng, L. (eds) Extracellular Vesicles. Springer, Singapore. https://doi.org/10.1007/978-981-99-8365-0_31

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  • DOI: https://doi.org/10.1007/978-981-99-8365-0_31

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  • Online ISBN: 978-981-99-8365-0

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