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Natural Hydrogels as Wound Dressing for Skin Wound-Healing Applications

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Interaction of Nanomaterials With Living Cells

Abstract

Natural polymers are widely used to produce hydrogels for skin wound-healing applications. Hydrogels possess porosity, water absorption and water retention capability, mechanical properties, and biocompatibility. Also, bioactive molecules and metal nanoparticles can be added into hydrogels to improve antimicrobial and wound-healing properties, which are necessary for dressing. This chapter reviews the main physicochemical and biological properties of the natural hydrogels used as a wound dressing. The different natural polymers such as chitosan, alginate, cellulose, and gelatin and fabrication methods to produce hydrogels are described. This chapter will contribute to a better understanding of natural hydrogels as a potential dressing for skin wound-healing applications.

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Acknowledgments

The authors thank the Universidad de Guadalajara-Centro Universitario de los Valles (UdG-CUVALLES) for their support through Programa PROSNI-Apoyo a la Mejora en las Condiciones de Producción SNI y SNCA (2023).

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Correspondence to Rogelio Rodríguez-Rodríguez .

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This research was funded by “Fomento a la Investigación 2022-2023 Centro Universitario de los Valles (CUVALLES)-Universidad de Guadalajara” grant number 267758.

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Fletes-Vargas, G., Rodríguez-Preciado, S.Y., Díaz-Zaragoza, M., Rodríguez-Rodríguez, R. (2023). Natural Hydrogels as Wound Dressing for Skin Wound-Healing Applications. In: Sheikh, F.A., Majeed, S., Beigh, M.A. (eds) Interaction of Nanomaterials With Living Cells. Springer, Singapore. https://doi.org/10.1007/978-981-99-2119-5_15

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