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Genetic Cell Therapy in Anti-Aging Regenerative Cosmetology

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Handbook of Stem Cell Applications

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Abstract

Anti-Aging Regenerative Cosmetology (AARC) is a patented technology for beautifying and strengthening the human body using live cells to enhance the appearance and function of various body parts to provide health and aestheticism to the individual throughout life. It is a combined cosmetic and preventive medicine to intervene with and correct the undesirable phenotypic expression of aging. The intrinsic properties of myoblasts and foreskin fibroblasts in development and regeneration are harnessed to formulate a genetic cell therapy program that is safe and efficacious, as previously tested in FDA Phase III clinical trials. Myoblasts are selected for strength development and foreskin fibroblasts for tenacity and smooth-to-the-touch. Both cell types are highly mitotic and non-carcinogenic. In addition to providing large quantities of nuclei as regenerative gene medicine and mitochondria as energy generators, myoblasts secret tumor necrosis factor-alpha (TNF-α) for skin whitening and melanoma prevention. Myoblasts, because of their small size, spindle shape, and resilience, grow readily on collagen and laminin within wrinkles of skin surfaces, thus enhancing the color, luster, and texture of the skin “plated” with them. Alternatively, they can be injected subcutaneously as cell fillers to reduce wrinkles. Intramuscular injection of myoblasts can augment muscle groups’ size, shape, consistency, tone, and strength, improving the lines, contours, and vitality to sculpt a youthful appearance. By improving cell genetics and organ functions, the program promises to sustain the human subject in good health and appearance, with a good quality of life and prolonged life.

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Abbreviations

BMP:

Bone morphogenic proteins

DMD:

Duchenne muscular dystrophy

FDA :

Food and Drug Administration

LGMD:

Limb-girdle muscular dystrophy

MTT:

Myoblast transfer therapy

SUI:

Stressed urinary incontinence

TNF:

Tumor necrosis factor-alpha

VEGF:

Vascular endothelial growth factor

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Acknowledgments

This work was supported by the Cell Therapy Institute (China) Endowment Fund. Professor Peter K. Law is a Distinguished Scientist in China.

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Authors and Affiliations

  1. Cell Therapy Institute, Wuhan, China

    Peter K. Law, Danlin M. Law, Ping Lu & Ming Zhang Ao

  2. Huazhong University of Science and Technology, Wuhan, China

    Peter K. Law, Ming Zhang Ao, Minxin Angela Zhao & Long Jiang Yu

  3. Wuhan University Affiliated Tong Ren Hospital, Wuhan, China

    Jun Ren & Ting Jiang

  4. Department of Plastic Surgery, First Affiliate Hospital of Zhengzhou University, Zhengzhou, China

    Ximei Wang

  5. Department of Medical Cosmetology, Beijing Tiantan Hospital Affiliated Capital Medical University, Beijing, China

    Li Jingyi

  6. Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, Al, USA

    Lei Ye

  7. Department of Basic Sciences, Sulaiman AlRajhi Colleges, Al Bukairiyah, Saudi Arabia

    Husnain Kh. Haider

Authors
  1. Peter K. Law
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  2. Jun Ren
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  4. Li Jingyi
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  5. Lei Ye
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  6. Husnain Kh. Haider
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  7. Danlin M. Law
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  8. Ping Lu
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  9. Ming Zhang Ao
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  10. Ting Jiang
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  11. Minxin Angela Zhao
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  12. Long Jiang Yu
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Corresponding author

Correspondence to Peter K. Law .

Editor information

Editors and Affiliations

  1. Department of Basic Sciences, Sulaiman Alrajhi University, AlQaseem, Saudi Arabia

    Khawaja H. Haider

Section Editor information

  1. Basic Sciences Department, Sulaiman AlRajhi University, AlQaseem, Saudi Arabia

    Khawaja Husnain Haider Ph.D

  2. McGill University, Montreal, QC, Canada

    Simon D. Tran

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Law, P.K. et al. (2023). Genetic Cell Therapy in Anti-Aging Regenerative Cosmetology. In: Haider, K.H. (eds) Handbook of Stem Cell Applications. Springer, Singapore. https://doi.org/10.1007/978-981-99-0846-2_31-1

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  • DOI: https://doi.org/10.1007/978-981-99-0846-2_31-1

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-0846-2

  • Online ISBN: 978-981-99-0846-2

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