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Radiotherapy, Chemotherapy, and Quality of Life

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Essentials of Rhinology

Abstract

The decision needs to be made in a multidisciplinary clinical team. Paranasal sinus malignancies are rare aggressive tumors. Radiotherapy is an integral part of management either as a single modality or in combination. There is a wide range of histopathological entities in this subtype with varying radiation sensitivity. Local failure is the major pattern of relapse. Lymph nodal involvement is less frequent in nasal and paranasal sinus malignancies although in cases of nasopharyngeal cancers it is present in up to 90% of the cases. The advent of advanced technologies in the form of IMRT and particle therapy substantially improved the clinical outcome. Conformal treatment provides high rates of local control with decreased toxicities. Margin positivity and extracapsular spread in lymph nodes are the indications for chemotherapy.

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Correspondence to Suman Bhasker .

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Devnani, B., Bhasker, S., Pramanik, R., Vadlamani, S.P., Mani, S. (2021). Radiotherapy, Chemotherapy, and Quality of Life. In: Verma, H., Thakar, A. (eds) Essentials of Rhinology. Springer, Singapore. https://doi.org/10.1007/978-981-33-6284-0_10

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  • DOI: https://doi.org/10.1007/978-981-33-6284-0_10

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