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Surgical Management of Gestational Trophoblastic Disease

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Gestational Trophoblastic Disease

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Abstract

Gestational trophoblastic disease (GTD) is a spectrum of premalignant and malignant tumors that develop from placental tissue and thus are associated with pregnancy. Outcomes for GTD have significantly improved over the last few decades with overall cure rates now well over 90%. Chemotherapy is essential to the treatment of GTN and a key factor in the improved cure rates. Although surgery is not as frequently indicated or utilized in the management of GTD, there are key instances in which surgery plays an important role in improving patient outcomes. These instances include primary uterine evacuation of hydatidiform moles, primary hysterectomy for molar pregnancies and malignant GTN, secondary hysterectomy and/or other excisional procedures for chemotherapy-resistant disease, excisional procedures to improve chemotherapy response, and surgical management of disease complications. In this chapter, we will review in detail the indications for surgery in the management of GTD.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Colorado School of Medicine, Aurora, CO, USA

    Saketh R. Guntupalli & Marisa R. Moroney

Authors
  1. Saketh R. Guntupalli
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  2. Marisa R. Moroney
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Correspondence to Saketh R. Guntupalli .

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Editors and Affiliations

  1. Associate Professor, Department of Gynaecologic Oncology, Acharya Harihar Post Graduate Institute of Cancer, Cuttack, India

    Bhagyalaxmi Nayak

  2. Professor & Head, Department of Obstetrics and Gynecology, King George’s Medical University, Lucknow, India

    Uma Singh

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Guntupalli, S.R., Moroney, M.R. (2021). Surgical Management of Gestational Trophoblastic Disease. In: Nayak, B., Singh, U. (eds) Gestational Trophoblastic Disease. Springer, Singapore. https://doi.org/10.1007/978-981-33-4878-3_12

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  • DOI: https://doi.org/10.1007/978-981-33-4878-3_12

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-33-4877-6

  • Online ISBN: 978-981-33-4878-3

  • eBook Packages: MedicineMedicine (R0)

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