Abstract
The study of molecular systematics, where the concept was first introduced in Chap. 1, enables the elucidation of relationships among groups of organisms using molecular means. Molecular systematics allows us to unravel the evolutionary history embedded in the organism’s genetic material by reconstructing phylogenetic trees, which illuminate the driving forces behind speciation and biodiversity. This chapter focused on the molecular systematics of parasitic nematodes that afflict humans and animals, where the phylum Nematoda is the second-largest phylum in the kingdom Animalia. Relationships among the major groups were detailed, as evidenced through molecular phylogenetic studies performed over the decades. A summary of the major findings, together with significant milestones in elucidating parasitic nematode phylogenetic relationships, was discussed. With such vast species diversity, coupled with the complex nature of host-parasite relationships, a robust phylogenetic framework through the study of nematode molecular systematics is essential to make meaningful comparisons across taxa, for classification and the generation of evolutionary hypotheses for the phylum.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ahmad, A. A., Yang, X., Zhang, T., Wang, C., Zhou, C., Yan, X., Hassan, M., Ikram, M., & Hu, M. (2019). Characterization of the complete mitochondrial genome of Ostertagia trifurcata of small ruminants and its phylogenetic associations for the Trichostrongyloidea superfamily. Genes (Basel), 10(2). https://doi.org/10.3390/genes10020107
Anderson, R. (2009). Keys to the nematode parasites of vertebrates. CABI Publishing.
Barratt, J., Chan, D., Sandaradura, I., Malik, R., Spielman, D., Lee, R., Marriott, D., Harkness, J., Ellis, J., & Stark, D. (2016). Angiostrongylus cantonensis: A review of its distribution, molecular biology and clinical significance as a human pathogen. Parasitology, 143(9), 1087–1118. https://doi.org/10.1017/s0031182016000652
Bert, W., Leliaert, F., Vierstraete, A. R., Vanfleteren, J. R., & Borgonie, G. (2008). Molecular phylogeny of the Tylenchina and evolution of the female gonoduct (Nematoda: Rhabditida). Molecular Phylogenetics and Evolution, 48(2), 728–744. https://doi.org/10.1016/j.ympev.2008.04.011
Bik, H. M., Lambshead, P. J., Thomas, W. K., & Lunt, D. H. (2010). Moving towards a complete molecular framework of the Nematoda: A focus on the Enoplida and early-branching clades. BMC Evolutionary Biology, 10, 353. https://doi.org/10.1186/1471-2148-10-353
Blaxter, M. (2000). Genes and genomes of Necator americanus and related hookworms. International Journal for Parasitology, 30(4), 347–355. https://doi.org/10.1016/s0020-7519(99)00198-8
Blaxter, M., & Koutsovoulos, G. (2015). The evolution of parasitism in Nematoda. Parasitology, 142(Suppl 1), S26–S39. https://doi.org/10.1017/S0031182014000791
Blaxter, M. L., De Ley, P., Garey, J. R., Liu, L. X., Scheldeman, P., Vierstraete, A., Vanfleteren, J. R., Mackey, L. Y., Dorris, M., Frisse, L. M., Vida, J. T., & Thomas, W. K. (1998). A molecular evolutionary framework for the phylum Nematoda. Nature, 392(6671), 71–75. https://doi.org/10.1038/32160
Borba, V. H., Machado-Silva, J. R., Le Bailly, M., & Iniguez, A. M. (2019). Worldwide paleodistribution of capillariid parasites: Paleoparasitology, current status of phylogeny and taxonomic perspectives. PLoS One, 14(4), e0216150. https://doi.org/10.1371/journal.pone.0216150
Callejon, R., Cutillas, C., & Nadler, S. A. (2015). Nuclear and mitochondrial genes for inferring Trichuris phylogeny. Parasitology Research, 114(12), 4591–4599. https://doi.org/10.1007/s00436-015-4705-7
Carreno, R. A., & Nadler, S. A. (2003). Phylogenetic analysis of the Metastrongyloidea (Nematoda: Strongylida) inferred from ribosomal RNA gene sequences. The Journal of Parasitology, 89(5), 965–973. https://doi.org/10.1645/ge-76r
CDC. (2020a). Biology - Life cycle of Capillaria philippinensis. https://www.cdc.gov/parasites/capillaria/biology_c_philippinensis.html
CDC. (2020b). Parasites - Enterobiasis (also known as Pinworm infection). https://www.cdc.gov/parasites/pinworm/
Chan, A. H. E., Chaisiri, K., Dusitsittipon, S., Jakkul, W., Charoennitiwat, V., Komalamisra, C., & Thaenkham, U. (2020a). Mitochondrial ribosomal genes as novel genetic markers for discrimination of closely related species in the Angiostrongylus cantonensis lineage. Acta Tropica, 211, 105645. https://doi.org/10.1016/j.actatropica.2020.105645
Chan, A. H. E., Chaisiri, K., Morand, S., Saralamba, N., & Thaenkham, U. (2020b). Evaluation and utility of mitochondrial ribosomal genes for molecular systematics of parasitic nematodes. Parasites & Vectors, 13(1), 364. https://doi.org/10.1186/s13071-020-04242-8
Chilton, N. B., Huby-Chilton, F., Gasser, R. B., & Beveridge, I. (2006). The evolutionary origins of nematodes within the order Strongylida are related to predilection sites within hosts. Molecular Phylogenetics and Evolution, 40(1), 118–128. https://doi.org/10.1016/j.ympev.2006.01.003
Chitwood, B. G. (1937). A revised classification of the Nematoda. In Papers on helminthology, 30 year jubileum (pp. 67–79). Lenin Academy of Agricultural Sciences.
De Ley, P. (2006). A quick tour of nematode diversity and the backbone of nematode phylogeny. WormBook, 1–8. https://www.ncbi.nlm.nih.gov/books/NBK19684/
De Ley, P., & Blaxter, M. (2002). Systematic position and phylogeny. In The biology of nematodes (pp. 1–30). Taylor & Francis.
Di Cesare, A., Castagna, G., Otranto, D., Meloni, S., Milillo, P., Latrofa, M. S., Paoletti, B., Bartolini, R., & Traversa, D. (2012). Molecular detection of Capillaria aerophila, an agent of canine and feline pulmonary capillariosis. Journal of Clinical Microbiology, 50(6), 1958–1963. https://doi.org/10.1128/JCM.00103-12
Dorris, M., De Ley, P., & Blaxter, M. L. (1999). Molecular analysis of nematode diversity and the evolution of parasitism. Parasitology Today, 15(5), 188–193. https://doi.org/10.1016/s0169-4758(99)01439-8
Dorris, M., Viney, M. E., & Blaxter, M. L. (2002). Molecular phylogenetic analysis of the genus Strongyloides and related nematodes. International Journal for Parasitology, 32(12), 1507–1517. https://doi.org/10.1016/s0020-7519(02)00156-x
Dusitsittipon, S., Criscione, C. D., Morand, S., Komalamisra, C., & Thaenkham, U. (2018). Hurdles in the evolutionary epidemiology of Angiostrongylus cantonensis: Pseudogenes, incongruence between taxonomy and DNA sequence variants, and cryptic lineages. Evolutionary Applications, 11(8), 1257–1269. https://doi.org/10.1111/eva.12621
Eamsobhana, P., Lim, P. E., & Yong, H. S. (2015). Phylogenetics and systematics of Angiostrongylus lungworms and related taxa (Nematoda: Metastrongyloidea) inferred from the nuclear small subunit (SSU) ribosomal DNA sequences. Journal of Helminthology, 89(3), 317–325. https://doi.org/10.1017/s0022149x14000108
Eberhardt, A. T., Robles, M. D. R., Monje, L. D., Beldomenico, P. M., & Callejón, R. (2019). A new Trichuris species (Nematoda: Trichuridae) from capybaras: Morphological-molecular characterization and phylogenetic relationships. Acta Tropica, 190, 244–252. https://doi.org/10.1016/j.actatropica.2018.11.029
El-Dib, N. A., El-Badry, A. A., Ta-Tang, T. H., & Rubio, J. M. (2015). Molecular detection of Capillaria philippinensis: An emerging zoonosis in Egypt. Experimental Parasitology, 154, 127–133. https://doi.org/10.1016/j.exppara.2015.04.011
Gao, J. F., Liu, G. H., Duan, H., Gao, Y., Zhang, Y., Chang, Q. C., Fang, M., & Wang, C. R. (2017a). Complete mitochondrial genomes of Triodontophorus serratus and Triodontophorus nipponicus, and their comparison with Triodontophorus brevicauda. Experimental Parasitology, 181, 88–93. https://doi.org/10.1016/j.exppara.2017.08.002
Gao, J. F., Zhao, Q., Liu, G. H., Zhang, Y., Zhang, Y., Wang, W. T., Chang, Q. C., Wang, C. R., & Zhu, X. Q. (2014). Comparative analyses of the complete mitochondrial genomes of the two ruminant hookworms Bunostomum trigonocephalum and Bunostomum phlebotomum. Gene, 541(2), 92–100. https://doi.org/10.1016/j.gene.2014.03.017
Gao, Y., Qiu, J. H., Zhang, B. B., Su, X., Fu, X., Yue, D. M., & Wang, C. R. (2017b). Complete mitochondrial genome of parasitic nematode Cylicocyclus nassatus and comparative analyses with Cylicocyclus insigne. Experimental Parasitology, 172, 18–22. https://doi.org/10.1016/j.exppara.2016.11.005
Gouy de Bellocq, J., Ferte, H., Depaquit, J., Justine, J. L., Tillier, A., & Durette-Desset, M. C. (2001). Phylogeny of the Trichostrongylina (Nematoda) inferred from 28S rDNA sequences. Molecular Phylogenetics and Evolution, 19(3), 430–442. https://doi.org/10.1006/mpev.2001.0925
Guardone, L., Deplazes, P., Macchioni, F., Magi, M., & Mathis, A. (2013). Ribosomal and mitochondrial DNA analysis of Trichuridae nematodes of carnivores and small mammals. Veterinary Parasitology, 197(1–2), 364–369. https://doi.org/10.1016/j.vetpar.2013.06.022
Hasegawa, H., Hayashida, S., Ikeda, Y., & Sato, H. (2009). Hyper-variable regions in 18S rDNA of Strongyloides spp. as markers for species-specific diagnosis. Parasitology Research, 104(4), 869–874. https://doi.org/10.1007/s00436-008-1269-9
Hawash, M. B., Andersen, L. O., Gasser, R. B., Stensvold, C. R., & Nejsum, P. (2015). Mitochondrial genome analyses suggest multiple Trichuris species in humans, baboons, and pigs from different geographical regions. PLoS Neglected Tropical Diseases, 9(9), e0004059. https://doi.org/10.1371/journal.pntd.0004059
Hawash, M. B., Betson, M., Al-Jubury, A., Ketzis, J., LeeWillingham, A., Bertelsen, M. F., Cooper, P. J., Littlewood, D. T., Zhu, X. Q., & Nejsum, P. (2016). Whipworms in humans and pigs: Origins and demography. Parasites & Vectors, 9, 37. https://doi.org/10.1186/s13071-016-1325-8
Holterman, M., Karssen, G., van den Elsen, S., van Megen, H., Bakker, J., & Helder, J. (2009). Small subunit rDNA-based phylogeny of the Tylenchida sheds light on relationships among some high-impact plant-parasitic nematodes and the evolution of plant feeding. Phytopathology, 99(3), 227–235. https://doi.org/10.1094/phyto-99-3-0227
Holterman, M., van der Wurff, A., van den Elsen, S., van Megen, H., Bongers, T., Holovachov, O., Bakker, J., & Helder, J. (2006). Phylum-wide analysis of SSU rDNA reveals deep phylogenetic relationships among nematodes and accelerated evolution toward crown clades. Molecular Biology and Evolution, 23(9), 1792–1800. https://doi.org/10.1093/molbev/msl044
Hoste, H., Chilton, N. B., Beveridge, I., & Gasser, R. B. (1998). A comparison of the first internal transcribed spacer of ribosomal DNA in seven species of Trichostrongylus (Nematoda: Trichostrongylidae). International Journal for Parasitology, 28(8), 1251–1260. https://doi.org/10.1016/s0020-7519(98)00093-9
Howe, K. L., Bolt, B. J., Shafie, M., Kersey, P., & Berriman, M. (2017). WormBase ParaSite - A comprehensive resource for helminth genomics. Molecular and Biochemical Parasitology, 215, 2–10. https://doi.org/10.1016/j.molbiopara.2016.11.005
Hu, L., Zhang, M., Sun, Y., & Bu, Y. (2020). Characterization and phylogenetic analysis of the first complete mitochondrial genome of Cylicocyclus radiatus. Veterinary Parasitology, 281, 109097. https://doi.org/10.1016/j.vetpar.2020.109097
Hu, M., Chilton, N. B., & Gasser, R. B. (2003). The mitochondrial genome of Strongyloides stercoralis (Nematoda) – Idiosyncratic gene order and evolutionary implications. International Journal for Parasitology, 33(12), 1393–1408. https://doi.org/10.1016/s0020-7519(03)00130-9
Hung, G. C., Chilton, N. B., Beveridge, I., & Gasser, R. B. (2000). A molecular systematic framework for equine strongyles based on ribosomal DNA sequence data. International Journal for Parasitology, 30(1), 95–103. https://doi.org/10.1016/s0020-7519(99)00166-6
Hunt, V. L., Hino, A., Yoshida, A., & Kikuchi, T. (2018). Comparative transcriptomics gives insights into the evolution of parasitism in Strongyloides nematodes at the genus, subclade and species level. Scientific Reports, 8(1), 5192. https://doi.org/10.1038/s41598-018-23514-z
Hunt, V. L., Tsai, I. J., Coghlan, A., Reid, A. J., Holroyd, N., Foth, B. J., Tracey, A., Cotton, J. A., Stanley, E. J., Beasley, H., Bennett, H. M., Brooks, K., Harsha, B., Kajitani, R., Kulkarni, A., Harbecke, D., Nagayasu, E., Nichol, S., Ogura, Y., … Berriman, M. (2016). The genomic basis of parasitism in the Strongyloides clade of nematodes. Nature Genetics, 48(3), 299–307. https://doi.org/10.1038/ng.3495
International Helminth Genomes Consortium. (2019). Comparative genomics of the major parasitic worms. Nature Genetics, 51(1), 163–174. https://doi.org/10.1038/s41588-018-0262-1
Jex, A. R., Hall, R. S., Littlewood, D. T., & Gasser, R. B. (2010). An integrated pipeline for next-generation sequencing and annotation of mitochondrial genomes. Nucleic Acids Research, 38(2), 522–533. https://doi.org/10.1093/nar/gkp883
Kampfer, S., Sturmbauer, C., & Ott, J. (1998). Phylogenetic analysis of rDNA sequences from adenophorean nematodes and implications for the Adenophorea-Secernentea controversy. Invertebrate Biology, 117(1), 29–36. https://doi.org/10.2307/3226849
Kang, S., Sultana, T., Eom, K. S., Park, Y. C., Soonthornpong, N., Nadler, S. A., & Park, J. K. (2009). The mitochondrial genome sequence of Enterobius vermicularis (Nematoda: Oxyurida)--an idiosyncratic gene order and phylogenetic information for chromadorean nematodes. Gene, 429(1–2), 87–97. https://doi.org/10.1016/j.gene.2008.09.011
Kern, E. M. A., Kim, T., & Park, J.-K. (2020). The mitochondrial genome in nematode phylogenetics. Frontiers in Ecology and Evolution, 8. https://doi.org/10.3389/fevo.2020.00250
Kikuchi, T., Afrin, T., & Yoshida, M. (2016). Complete mitochondrial genomes of four entomopathogenic nematode species of the genus Steinernema. Parasites & Vectors, 9(1), 430. https://doi.org/10.1186/s13071-016-1730-z
Kim, J., Lee, S.-H., Gazi, M., Kim, T., Jung, D., Chun, J.-Y., Kim, S., Seo, T.-K., Park, C., Baldwin, J. G., Nadler, S. A., & Park, J.-K. (2015). Mitochondrial genomes advance phylogenetic hypotheses for Tylenchina (Nematoda: Chromadorea). Zoologica Scripta, 44(4), 446–462. https://doi.org/10.1111/zsc.12112
Ko, P. P., Sakaguchi, K., Yoshida, A., Maruyama, H., Nonaka, N., & Nagayasu, E. (2019). First molecular identification of Strongyloides vituli in cattle in Japan and insights into the evolutionary history of Strongyloides parasites of ruminants. Parasitology International, 72, 101937. https://doi.org/10.1016/j.parint.2019.101937
Kumar, S., Koutsovoulos, G., Kaur, G., & Blaxter, M. (2012). Toward 959 nematode genomes. Worm, 1(1), 42–50. https://doi.org/10.4161/worm.19046
Laetsch, D. R., Heitlinger, E. G., Taraschewski, H., Nadler, S. A., & Blaxter, M. L. (2012). The phylogenetics of Anguillicolidae (Nematoda: Anguillicoloidea), swimbladder parasites of eels. BMC Evolutionary Biology, 12, 60. https://doi.org/10.1186/1471-2148-12-60
Li, K., Shahzad, M., Zhang, H., Mehmood, K., Jiang, X., Luo, H., Zhang, L., Dong, X., & Li, J. (2018b). Characterization of the complete mitochondrial genome of Metastrongylus salmi (M. salmi) derived from Tibetan pigs in Tibet, China. Acta Parasitologica, 63(2), 280–286. https://doi.org/10.1515/ap-2018-0032
Li, L., Lu, L., Nadler, S. A., Gibson, D. I., Zhang, L. P., Chen, H. X., Zhao, W. T., & Guo, Y. N. (2018a). Molecular phylogeny and dating reveal a terrestrial origin in the early carboniferous for ascaridoid nematodes. Systematic Biology, 67(5), 888–900. https://doi.org/10.1093/sysbio/syy018
Li, Y., Chen, H. X., Yang, X. L., & Li, L. (2019). Morphological and genetic characterization of Syphabulea tjanschani (Nematoda: Oxyuridae), with phylogenetic position of Syphabulea in Oxyuridae. Infection, Genetics and Evolution, 67, 159–166. https://doi.org/10.1016/j.meegid.2018.11.016
Li, Y., Niu, L., Wang, Q., Zhang, Z., Chen, Z., Gu, X., Xie, Y., Yan, N., Wang, S., Peng, X., & Yang, G. (2012). Molecular characterization and phylogenetic analysis of ascarid nematodes from twenty-one species of captive wild mammals based on mitochondrial and nuclear sequences. Parasitology, 139(10), 1329–1338. https://doi.org/10.1017/S003118201200056X
Liu, G. H., Gasser, R. B., Su, A., Nejsum, P., Peng, L., Lin, R. Q., Li, M. W., Xu, M. J., & Zhu, X. Q. (2012). Clear genetic distinctiveness between human- and pig-derived Trichuris based on analyses of mitochondrial datasets. PLoS Neglected Tropical Diseases, 6(2), e1539. https://doi.org/10.1371/journal.pntd.0001539
Liu, G. H., Li, S., Zou, F. C., Wang, C. R., & Zhu, X. Q. (2016a). The complete mitochondrial genome of rabbit pinworm Passalurus ambiguus: Genome characterization and phylogenetic analysis. Parasitology Research, 115(1), 423–429. https://doi.org/10.1007/s00436-015-4778-3
Liu, G. H., Nadler, S. A., Liu, S. S., Podolska, M., D’Amelio, S., Shao, R., Gasser, R. B., & Zhu, X. Q. (2016b). Mitochondrial phylogenomics yields strongly supported hypotheses for ascaridomorph nematodes. Scientific Reports, 6, 39248. https://doi.org/10.1038/srep39248
Liu, G. H., Shao, R., Cai, X. Q., Li, W. W., & Zhu, X. Q. (2015). Gnathostoma spinigerum mitochondrial genome sequence: A novel gene arrangement and its phylogenetic position within the class Chromadorea. Scientific Reports, 5, 12691. https://doi.org/10.1038/srep12691
Liu, G. H., Shao, R., Li, J. Y., Zhou, D. H., Li, H., & Zhu, X. Q. (2013). The complete mitochondrial genomes of three parasitic nematodes of birds: A unique gene order and insights into nematode phylogeny. BMC Genomics, 14(1), 414. https://doi.org/10.1186/1471-2164-14-414
Lorenzen, S. (1994). The phylogenetic systematics of free-living nematodes. Ray Society.
Maggenti, A. R. (1983). Nematode higher classification as influenced by species and family concepts. In Concepts in nematode systematics (pp. 25–40). Academic press.
Meldal, B. H., Debenham, N. J., De Ley, P., De Ley, I. T., Vanfleteren, J. R., Vierstraete, A. R., Bert, W., Borgonie, G., Moens, T., Tyler, P. A., Austen, M. C., Blaxter, M. L., Rogers, A. D., & Lambshead, P. J. (2007). An improved molecular phylogeny of the Nematoda with special emphasis on marine taxa. Molecular Phylogenetics and Evolution, 42(3), 622–636. https://doi.org/10.1016/j.ympev.2006.08.025
Meng, X., Xie, Y., Gu, X., Zheng, Y., Liu, Y., Li, Y., Wang, L., Zhou, X., Zuo, Z., & Yang, G. (2019). Sequencing and analysis of the complete mitochondrial genome of dog roundworm Toxocara canis (Nematoda: Toxocaridae) from USA. Mitochondrial DNA. Part B, Resources, 4(2), 2999–3001. https://doi.org/10.1080/23802359.2019.1666042
Mitreva, M., Blaxter, M. L., Bird, D. M., & McCarter, J. P. (2005). Comparative genomics of nematodes. Trends in Genetics, 21(10), 573–581. https://doi.org/10.1016/j.tig.2005.08.003
Mohandas, N., Pozio, E., La Rosa, G., Korhonen, P. K., Young, N. D., Koehler, A. V., Hall, R. S., Sternberg, P. W., Boag, P. R., Jex, A. R., Chang, B. C., & Gasser, R. B. (2014). Mitochondrial genomes of Trichinella species and genotypes - A basis for diagnosis, and systematic and epidemiological explorations. International Journal for Parasitology, 44(14), 1073–1080. https://doi.org/10.1016/j.ijpara.2014.08.010
Nadler, S. A., Carreno, R. A., Mejia-Madrid, H., Ullberg, J., Pagan, C., Houston, R., & Hugot, J. P. (2007). Molecular phylogeny of clade III nematodes reveals multiple origins of tissue parasitism. Parasitology, 134(Pt 10), 1421–1442. https://doi.org/10.1017/S0031182007002880
Nadler, S. A., De Ley, P., Mundo-Ocampo, M., Smythe, A. B., Patricia Stock, S., Bumbarger, D., Adams, B. J., De Ley, I. T., Holovachov, O., & Baldwin, J. G. (2006). Phylogeny of Cephalobina (Nematoda): Molecular evidence for recurrent evolution of probolae and incongruence with traditional classifications. Molecular Phylogenetics and Evolution, 40(3), 696–711. https://doi.org/10.1016/j.ympev.2006.04.005
Nagayasu, E., Aung, M., Hortiwakul, T., Hino, A., Tanaka, T., Higashiarakawa, M., Olia, A., Taniguchi, T., Win, S. M. T., Ohashi, I., Odongo-Aginya, E. I., Aye, K. M., Mon, M., Win, K. K., Ota, K., Torisu, Y., Panthuwong, S., Kimura, E., Palacpac, N. M. Q., … Maruyama, H. (2017). A possible origin population of pathogenic intestinal nematodes, Strongyloides stercoralis, unveiled by molecular phylogeny. Scientific Reports, 7(1), 4844. https://doi.org/10.1038/s41598-017-05049-x
Paguem, A., Abanda, B., Ngwasiri, N. N., Eisenbarth, A., Renz, A., Streit, A., & Achukwi, M. D. (2020). Host specificity and phylogeny of Trichostrongylidae of domestic ruminants in the Guinea savannah of the Adamawa plateau in Cameroon. Veterinary Parasitology, Regional Studies and Reports, 21, 100412. https://doi.org/10.1016/j.vprsr.2020.100412
Park, J. K., Sultana, T., Lee, S. H., Kang, S., Kim, H. K., Min, G. S., Eom, K. S., & Nadler, S. A. (2011). Monophyly of clade III nematodes is not supported by phylogenetic analysis of complete mitochondrial genome sequences. BMC Genomics, 12, 392. https://doi.org/10.1186/1471-2164-12-392
Perkins, S. L., Martinsen, E. S., & Falk, B. G. (2011). Do molecules matter more than morphology? Promises and pitfalls in parasites. Parasitology, 138(13), 1664–1674. https://doi.org/10.1017/s0031182011000679
Pozio, E., Hoberg, E., La Rosa, G., & Zarlenga, D. S. (2009). Molecular taxonomy, phylogeny and biogeography of nematodes belonging to the Trichinella genus. Infection, Genetics and Evolution, 9(4), 606–616. https://doi.org/10.1016/j.meegid.2009.03.003
Pozio, E., & Zarlenga, D. S. (2005). Recent advances on the taxonomy, systematics and epidemiology of Trichinella. International Journal for Parasitology, 35(11–12), 1191–1204. https://doi.org/10.1016/j.ijpara.2005.07.012
Ricciardi, A., & Ndao, M. (2015). Diagnosis of parasitic infections: What’s going on? Journal of Biomolecular Screening, 20(1), 6–21. https://doi.org/10.1177/1087057114548065
Rivero, J., Callejon, R., & Cutillas, C. (2021). Complete mitochondrial genome of Trichuris trichiura from Macaca sylvanus and Papio papio. Life (Basel), 11(2). https://doi.org/10.3390/life11020126
Robles Mdel, R., Cutillas, C., Panei, C. J., & Callejón, R. (2014). Morphological and molecular characterization of a new Trichuris species (Nematoda- Trichuridae), and phylogenetic relationships of Trichuris species of Cricetid rodents from Argentina. PLoS One, 9(11), e112069. https://doi.org/10.1371/journal.pone.0112069
Sakaguchi, S., Yunus, M., Sugi, S., & Sato, H. (2020). Integrated taxonomic approaches to seven species of capillariid nematodes (Nematoda: Trichocephalida: Trichinelloidea) in poultry from Japan and Indonesia, with special reference to their 18S rDNA phylogenetic relationships. Parasitology Research, 119(3), 957–972. https://doi.org/10.1007/s00436-019-06544-y
Sharifdini, M., Derakhshani, S., Alizadeh, S. A., Ghanbarzadeh, L., Mirjalali, H., Mobedi, I., & Saraei, M. (2017a). Molecular identification and phylogenetic analysis of human Trichostrongylus species from an endemic area of Iran. Acta Tropica, 176, 293–299. https://doi.org/10.1016/j.actatropica.2017.07.001
Sharifdini, M., Heidari, Z., Hesari, Z., Vatandoost, S., & Kia, E. B. (2017b). Molecular phylogenetics of Trichostrongylus species (Nematoda: Trichostrongylidae) from humans of Mazandaran Province, Iran. Korean Journal of Parasitology, 55(3), 279–285. https://doi.org/10.3347/kjp.2017.55.3.279
Shi, X., Wang, M., Abdullahi, A. Y., Fu, Y., Yang, F., Yu, X., Pan, W., Yan, X., Hang, J., Zhang, P., & Li, G. (2018). Comparative analysis of Ancylostoma ceylanicum mitochondrial genome with other Ancylostoma species. Infection, Genetics and Evolution, 62, 40–45. https://doi.org/10.1016/j.meegid.2018.04.012
Smythe, A. B., Holovachov, O., & Kocot, K. M. (2019). Improved phylogenomic sampling of free-living nematodes enhances resolution of higher-level nematode phylogeny. BMC Evolutionary Biology, 19(1), 121. https://doi.org/10.1186/s12862-019-1444-x
Sultana, T., Kim, J., Lee, S.-H., Han, H., Kim, S., Min, G.-S., Nadler, S. A., & Park, J.-K. (2013). Comparative analysis of complete mitochondrial genome sequences confirms independent origins of plant-parasitic nematodes. BMC Evolutionary Biology, 13(1), 12. https://doi.org/10.1186/1471-2148-13-12
Sun, L., Zhuo, K., Lin, B., Wang, H., & Liao, J. (2014). The complete mitochondrial genome of Meloidogyne graminicola (Tylenchina): A unique gene arrangement and its phylogenetic implications. PLoS One, 9(6), e98558. https://doi.org/10.1371/journal.pone.0098558
Sun, M. M., Han, L., Zhang, F. K., Zhou, D. H., Wang, S. Q., Ma, J., Zhu, X. Q., & Liu, G. H. (2018). Characterization of the complete mitochondrial genome of Marshallagia marshalli and phylogenetic implications for the superfamily Trichostrongyloidea. Parasitology Research, 117(1), 307–313. https://doi.org/10.1007/s00436-017-5669-6
Valentyne, H., Spratt, D. M., Aghazadeh, M., Jones, M. K., & Šlapeta, J. (2020). The mitochondrial genome of Angiostrongylus mackerrasae is distinct from A. cantonensis and A. malaysiensis. Parasitology, 147(6), 681–688. https://doi.org/10.1017/s0031182020000232
van Megen, H., van den Elsen, S., Holterman, M., Karssen, G., Mooyman, P., Bongers, T., Holovachov, O., Bakker, J., & Helder, J. (2009). A phylogenetic tree of nematodes based on about 1200 full-length small subunit ribosomal DNA sequences. Nematology, 11(6), 927–950. https://doi.org/10.1163/156854109x456862
Wang, C. R., Gao, J. F., Zhu, X. Q., & Zhao, Q. (2012). Characterization of Bunostomum trigonocephalum and Bunostomum phlebotomum from sheep and cattle by internal transcribed spacers of nuclear ribosomal DNA. Research in Veterinary Science, 92(1), 99–102. https://doi.org/10.1016/j.rvsc.2010.10.024
Wang, C. R., Lou, Y., Gao, J. F., Qiu, J. H., Zhang, Y., Gao, Y., & Chang, Q. C. (2016). Comparative analyses of the complete mitochondrial genomes of the two murine pinworms Aspiculuris tetraptera and Syphacia obvelata. Gene, 585(1), 71–75. https://doi.org/10.1016/j.gene.2016.03.037
WHO. (2020). Soil-transmitted helminth infections. https://www.who.int/news-room/fact-sheets/detail/soil-transmitted-helminth-infections
Wijova, M., Moravec, F., Horak, A., & Lukes, J. (2006). Evolutionary relationships of Spirurina (Nematoda: Chromadorea: Rhabditida) with special emphasis on dracunculoid nematodes inferred from SSU rRNA gene sequences. International Journal for Parasitology, 36(9), 1067–1075. https://doi.org/10.1016/j.ijpara.2006.04.005
Yong, H. S., Song, S. L., Eamsobhana, P., & Lim, P. E. (2016). Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes. Acta Tropica, 161, 33–40. https://doi.org/10.1016/j.actatropica.2016.05.002
Zarlenga, D., Thompson, P., & Pozio, E. (2020). Trichinella species and genotypes. Research in Veterinary Science, 133, 289–296. https://doi.org/10.1016/j.rvsc.2020.08.012
Zarlenga, D. S., Rosenthal, B. M., La Rosa, G., Pozio, E., & Hoberg, E. P. (2006). Post-Miocene expansion, colonization, and host switching drove speciation among extant nematodes of the archaic genus Trichinella. Proceedings of the National Academy of Sciences of the United States of America, 103(19), 7354–7359. https://doi.org/10.1073/pnas.0602466103
Zhang, Y., Xu, W. W., Guo, D. H., Liu, Z. X., Duan, H., Su, X., Fu, X., Yue, D. M., Gao, Y., & Wang, C. R. (2015). The complete mitochondrial genome of Oxyuris equi: Comparison with other closely related species and phylogenetic implications. Experimental Parasitology, 159, 215–221. https://doi.org/10.1016/j.exppara.2015.09.013
Zou, H., Jakovlic, I., Chen, R., Zhang, D., Zhang, J., Li, W. X., & Wang, G. T. (2017). The complete mitochondrial genome of parasitic nematode Camallanus cotti: Extreme discontinuity in the rate of mitogenomic architecture evolution within the Chromadorea class. BMC Genomics, 18(1), 840. https://doi.org/10.1186/s12864-017-4237-x
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Thaenkham, U., Chaisiri, K., Hui En Chan, A. (2022). Molecular Systematics of Parasitic Nematodes. In: Molecular Systematics of Parasitic Helminths . Springer, Singapore. https://doi.org/10.1007/978-981-19-1786-8_10
Download citation
DOI: https://doi.org/10.1007/978-981-19-1786-8_10
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-19-1785-1
Online ISBN: 978-981-19-1786-8
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)