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Implications and Future Perspectives

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Microbes and Oral Squamous Cell Carcinoma

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Abstract

The oral microbiome is considered to be the most diverse in the human body. Around 600–700 bacterial phylotypes have been detected in the oral cavity, most of which belong to the phyla Actinobacteria, Bacteroidetes, Firmicutes, Proteobacteria, Spirochaetes, Synergistetes, and Tenericutes, along with viruses, fungi, protozoa, mycoplasma, and archaea. The human oral cavity is divided into different subsites, including the gingiva, tongue, cheeks, hard and soft palates, hard tissues (teeth), exocrine gland tissue (major and minor salivary glands), supragingival plaque of tooth surfaces, subgingival plaque, maxillary anterior vestibule, and tonsils, all of which are colonized by distinct microbiota with unique features. The composition of the flora in all the subsites is different in healthy individuals and diseased. It is important to understand the composition of the microbiome and the factors that may influence its composition for the development of better diagnostic and therapeutic strategies.

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Authors and Affiliations

  1. Institute of Life Science, Bhubaneswar, Odisha, India

    Shaheerah Khan & Anshuman Dixit

  2. University of Nebraska—Lincoln, Lincoln, NE, USA

    Rohita Sinha

  3. Department of Dentistry, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Bhubaneswar, Odisha, India

    Samapika Routray

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  1. Shaheerah Khan
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  2. Rohita Sinha
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  3. Samapika Routray
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  4. Anshuman Dixit
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Correspondence to Anshuman Dixit .

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Editors and Affiliations

  1. Department of Dentistry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

    Samapika Routray

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Khan, S., Sinha, R., Routray, S., Dixit, A. (2022). Implications and Future Perspectives. In: Routray, S. (eds) Microbes and Oral Squamous Cell Carcinoma. Springer, Singapore. https://doi.org/10.1007/978-981-19-0592-6_13

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