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A Mach–Zehnder Ring Resonator Layout for Label Free Detection of Diabetes

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Proceedings of the 7th International Conference on the Applications of Science and Mathematics 2021

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 273))

Abstract

Most diabetic patients argue about the high price of the disposable test card together with an unpleasant and painful fasting blood test that must be repeated daily. In this work, a Mach–Zehnder interferometer was combined with a small size ring resonator system, including two half-circular racetrack ring resonators to set up a Mach–Zehnder ring resonator (MZRR) system for low cost and painless process of diabetes detection. In this work, patient’s tear was exploited instead of using blood samples to get rid of daily painful blood taking test. The optical transfer function of MZRR is derived using the signal flow graph method. The MZRR works based on a variation of the refractive indices of the test samples and any change in the refractive index of the top cladding sensing layer can cause a specific shift in output light resonance peaks. The sensitivity of the MZRR sensor for the detection of diabetes is measured to be 360 nm/RIU, which leads to a detection limit of 5.5 × 10–5 RIU. The advantages of the MZRR sensor are in high accuracy, the quick approach of detection and a painless process, which make the MZRR sensor a proper lab-on-chip device for health monitoring of diabetic patients.

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Acknowledgements

The authors would like to acknowledge for the research facilities of Shiraz University of Technology, Iran and Photonics Device and Sensor Research Centre (PDSR), Department of Physics and Chemistry, Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia.

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Authors and Affiliations

  1. Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, 71345-1978, Shiraz, Iran

    Parisa Sanati

  2. Department of Physics, Shiraz University of Technology, 31371555, Shiraz, Fars, Iran

    Mahdi Bahadoran

  3. Department of Physics and Chemistry, Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia, Pagoh Educational Hub, 86400, Muar, Johor, Malaysia

    Mohd Kamarulzaki Mustafa

Authors
  1. Parisa Sanati
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  2. Mahdi Bahadoran
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  3. Mohd Kamarulzaki Mustafa
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Corresponding author

Correspondence to Mohd Kamarulzaki Mustafa .

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Editors and Affiliations

  1. Universiti Tun Hussein Onn Malaysia, Johor, Malaysia

    Aida Binti Mustapha

  2. Universiti Tun Hussein Onn Malaysia, Johor, Malaysia

    Suhadir Shamsuddin

  3. Universiti Tun Hussein Onn Malaysia, Johor, Malaysia

    Syed Zuhaib Haider Rizvi

  4. Universiti Tun Hussein Onn Malaysia, Johor, Malaysia

    Saliza Binti Asman

  5. Universiti Tun Hussein Onn Malaysia, Johor, Malaysia

    Siti Suhana Jamaian

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Sanati, P., Bahadoran, M., Mustafa, M.K. (2022). A Mach–Zehnder Ring Resonator Layout for Label Free Detection of Diabetes. In: Mustapha, A.B., Shamsuddin, S., Zuhaib Haider Rizvi, S., Asman, S.B., Jamaian, S.S. (eds) Proceedings of the 7th International Conference on the Applications of Science and Mathematics 2021. Springer Proceedings in Physics, vol 273. Springer, Singapore. https://doi.org/10.1007/978-981-16-8903-1_12

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