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Assessment of Osteoporosis by QCT, HR-pQCT, and MRI

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Osteoporotic Fracture and Systemic Skeletal Disorders

Abstract

Quantitative CT (QCT) is a method for evaluating bone mineral density (BMD) of the spine and proximal femur three-dimensionally by combining clinical CT with a bone density phantom and dedicated software. It is possible to measure BMD more accurately than with dual energy X-ray absorptiometry (DXA).

High-resolution peripheral quantitative CT (HR-pQCT) is a small-sized clinical CT dedicated to bone research, and its high resolution (voxel size 61 μm) enables analysis of the bone microstructure of living patients noninvasively. It shows osteoporotic changes at the bone microstructure level, such as decreased trabecular number, cortical thickness, and increased cortical porosity.

The present invited review was completed and submitted to the publisher on 01-Jul-20. 

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Authors and Affiliations

  1. Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

    Ko Chiba & Makoto Osaki

  2. The Open University of Japan, Nagasaki, Japan

    Masako Ito

Authors
  1. Ko Chiba
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  2. Makoto Osaki
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  3. Masako Ito
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Corresponding author

Correspondence to Ko Chiba .

Editor information

Editors and Affiliations

  1. Niigata Bone Science Institute, Niigata Rehabilitation Hospital, Niigata, Japan

    Hideaki E. Takahashi

  2. Department of Anatomy, Cell Biology and Physiology, Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA

    David B. Burr

  3. Niigata Bone Science Institute, Niigata Rehabilitation Hospital, Niigata, Japan

    Noriaki Yamamoto

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Chiba, K., Osaki, M., Ito, M. (2022). Assessment of Osteoporosis by QCT, HR-pQCT, and MRI. In: Takahashi, H.E., Burr, D.B., Yamamoto, N. (eds) Osteoporotic Fracture and Systemic Skeletal Disorders. Springer, Singapore. https://doi.org/10.1007/978-981-16-5613-2_11

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  • DOI: https://doi.org/10.1007/978-981-16-5613-2_11

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-16-5612-5

  • Online ISBN: 978-981-16-5613-2

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