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Synthesis and Processing of Magnetic-Based Nanomaterials for Biomedical Applications

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Handbook on Synthesis Strategies for Advanced Materials

Part of the book series: Indian Institute of Metals Series ((IIMS))

Abstract

Recent developments in the design, synthesis, and processing of magnetic nanomaterials have gained immense attention for various biomedical applications. Magnetic nanomaterial-mediated therapy and diagnostic applications have opened up new avenues for cancer therapy in terms of non-toxicity, biocompatibility, chemical stability, size, shape, and composition. This chapter covers a detailed account of the synthesis methods (chemical and biological) and the surface functionalization process determining the physico-chemical properties of the nanomaterials favorable for biomedical applications. Finally, a detailed overview of distinctive applications of magnetic-based nanomaterials in the field of magnetic hyperthermia, photothermal therapy, drug delivery, bioimaging and biosensing has been provided.

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Abbreviations

ACMF:

Alternating current magnetic field`

[bmim][BF4]:

1-Butyl-3-methylimidazolium tetrafluoroborate

CL:

Chemiluminescence

CNT:

Carbon nanotube

CPE:

Carbon paste electrode

cRGD:

Cyclic arginine-glycine-aspartate

CRP:

C-reactive protein

CT:

Computed tomography

CTAB:

Cetyltrimethylammonium bromide

CV:

Cyclic voltammetry

DMSA:

Dimercaptosuccinic acid

DNA:

Deoxyribonucleic acid

DOTA:

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid

DOX:

Doxorubicin

DPV:

Differential pulse voltammetry

EC:

Electrochemical

EPR:

Enhanced permeability and retention

FDA:

Food and Drug Administration

FITC:

Fluorescein isothiocyanate

GO:

Graphene oxide

IONPs:

Iron oxide nanoparticles

IR:

Infrared

LOD:

Low limit of detection

LSPR:

Localized surface plasmon resonance

MF:

Magnetic field

MHT:

Magnetic hyperthermia

MNPs:

Magnetic Nanoparticles

MRI:

Magnetic resonance imaging

MWA:

Microwave-assisted

MWCNTs:

Multi-walled carbon nanotubes

NIR:

Near-infrared

NMR:

Nuclear Magnetic Resonance

NOTA:

1,4,7-Triazacyclononane-N,N′,N″-triacetic acid

NPs:

Nanoparticles

PAA:

Polyacrylic acid

PAA-b-PS:

Poly (acrylic acid)-b-polystyrene

PANI:

Polyaniline

PDA:

Polydopamine

PEG:

Polyethylene glycol

PEGDE:

Pentaethylene glycol dodecyl ether

PEI:

Polyethylenimine

PET:

Positron emission tomography

PMMA:

Poly(methyl methacrylate)

PS:

Polystyrene

PTT:

Photothermal therapy

PVA:

Polyvinyl alcohol

PVP:

Polyvinylpyrrolidine

QCM:

Quartz-crystal microbalance

SAR:

Specific absorption rate

SPIONs:

Superparamagnetic iron oxide nanoparticles

SPR:

Surface plasmon resonance

TEM:

Transmission electron microscopy

TMA:

Thiomalic acid

TOPSe:

Trioctyl phosphine selenide

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Authors and Affiliations

  1. Centre for Nanotechnology Research, Vellore Institute of Technology, Vellore, 632014, India

    Arunima Rajan, R. K. Chandunika, Femy Raju & Niroj Kumar Sahu

  2. School of Advanced Sciences, Vellore Institute of Technology, Vellore, 632014, India

    Arunima Rajan & Femy Raju

  3. Chemistry Division, Bhabha Atomic Research Centre, Mumbai, 400085, India

    Rashmi Joshi & Raghumani Singh Ningthoujam

  4. Homi Bhabha National Institute, Mumbai, 400094, India

    Rashmi Joshi & Raghumani Singh Ningthoujam

Authors
  1. Arunima Rajan
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  2. R. K. Chandunika
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  3. Femy Raju
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  4. Rashmi Joshi
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  5. Niroj Kumar Sahu
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  6. Raghumani Singh Ningthoujam
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Corresponding authors

Correspondence to Niroj Kumar Sahu or Raghumani Singh Ningthoujam .

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Editors and Affiliations

  1. Chemistry Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India

    A. K. Tyagi

  2. Chemistry Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India

    Raghumani S. Ningthoujam

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Rajan, A., Chandunika, R.K., Raju, F., Joshi, R., Sahu, N.K., Ningthoujam, R.S. (2022). Synthesis and Processing of Magnetic-Based Nanomaterials for Biomedical Applications. In: Tyagi, A.K., Ningthoujam, R.S. (eds) Handbook on Synthesis Strategies for Advanced Materials. Indian Institute of Metals Series. Springer, Singapore. https://doi.org/10.1007/978-981-16-1803-1_16

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