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Silk Fibroin Bioinks for Digital Light Processing (DLP) 3D Bioprinting

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Bioinspired Biomaterials

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1249 ))

  • The original version of this chapter was revised: An earlier version of this chapter was published with an incorrect Acknowledgements text which has been updated now. The correction to this chapter is available at https://doi.org/10.1007/978-981-15-3258-0_15

Abstract

Three-dimensional (3D) bioprinting has been a highly influential technology in the field of tissue engineering to enable speedy and precise spatial patterning of cells, growth factors, and biomaterials. Bioink is one of the main factors in 3D bioprinting, and hydrogels are excellent matrix type by means of bioinks for 3D bioprinting. Recently, stereolithographic bioprinting via digital light processing (DLP) that allows high spatial resolution and rapid printing time of complex structures has attracted many studies. However, a small number of bioinks have been applied to DLP bioprinting in comparison with bioinks for other bioprinters. We developed a novel bioink based on silk fibroin that has been extensively used in biomedical fields due to its positive biological and biochemical properties as biomaterials. In this chapter, we summarized the silk fibroin basics and various applications of silk fibroin as printing material. Also, fabrication and performance of silk-based bioink for DLP bioprinter were discussed.

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Acknowledgments

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (grant No.: 2016R1E1A1A01942120), Republic of Korea and by the Hallym University Research Fund.

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Authors and Affiliations

  1. Nano-Bio Regenerative Medical Institute, College of Medicine, Hallym University, Chuncheon, Republic of Korea

    Soon Hee Kim, Do Yeon Kim, Tae Hyeon Lim & Chan Hum Park

  2. Departments of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, School of Medicine, Hallym University, Chuncheon, Republic of Korea

    Chan Hum Park

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  1. Soon Hee Kim
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Correspondence to Chan Hum Park .

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Editors and Affiliations

  1. Institute of Cell & Tissue Engineering and College of Medicine, Catholic University of Korea, Seoul, Korea (Republic of)

    Heung Jae Chun

  2. 3B’s Research Group, I3Bs – Research Institute on Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimarães, Portugal

    Rui L. Reis

  3. Department of Industrial Engineering and BIOtech Research Center, University of Trento, Trento, Italy

    Antonella Motta

  4. Department of BIN Convergence Technology, Department of Polymer Nano Science & Technology and Polymer BIN Research Center, Jeonbuk National University, Jeonju, Korea (Republic of)

    Gilson Khang

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Kim, S.H., Kim, D.Y., Lim, T.H., Park, C.H. (2020). Silk Fibroin Bioinks for Digital Light Processing (DLP) 3D Bioprinting. In: Chun, H.J., Reis, R.L., Motta, A., Khang, G. (eds) Bioinspired Biomaterials. Advances in Experimental Medicine and Biology, vol 1249 . Springer, Singapore. https://doi.org/10.1007/978-981-15-3258-0_4

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