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Cardiac output in hypertension

Basic concepts and experimental studies

  • Chapter
The Heart in Hypertension

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 98))

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Abstract

Simple hydrodynamic considerations indicate that the systemic blood flow from the aorta back to the heart is driven by the difference of total fluid energy between aorta and right atrium (RA), which for all practical purpose is equal to the gradient between mean arterial pressure and right atrial pressure, MAP — RAP. This flow can thus be calculated as MAP — RAP/TPR, where TPR is the total peripheral resistance. Systemic blood flow is equal to cardiac output (CO), and since RAP is small and does not change markedly under most conditions, the usual expression of these relations becomes: MAP = CO × TPR. Thus, mean arterial pressure is determined by cardiac output and peripheral resistance.

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Authors
  1. Jean-François Liard
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine and Hypertension Research Center, Broussais Hospital, Paris, France

    M. E. Safar

  2. Cleveland Clinic Foundation, Cleveland, Ohio, USA

    F. Fouad-Tarazi

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© 1989 Kluwer Academic Publishers

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Liard, JF. (1989). Cardiac output in hypertension. In: Safar, M.E., Fouad-Tarazi, F. (eds) The Heart in Hypertension. Developments in Cardiovascular Medicine, vol 98. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0941-0_3

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  • DOI: https://doi.org/10.1007/978-94-009-0941-0_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6913-7

  • Online ISBN: 978-94-009-0941-0

  • eBook Packages: Springer Book Archive

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