Overview
- Nominated by Hokkaido University as an outstanding thesis in chemistry
- First report that comprehensively and quantitatively analyzes the effects of tumor-derived mutations on tetrameric structure of tumor suppressor p53
- Reports the development of a new stabilizer and inhibitor of p53, which could enhance or decrease p53 transcriptional activity via regulation of tetramer formation of p53
- Includes supplementary material: sn.pub/extras
Part of the book series: Springer Theses (Springer Theses)
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Table of contents (5 chapters)
Keywords
About this book
Authors and Affiliations
About the author
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University
Bibliographic Information
Book Title: Tetramer Stability and Functional Regulation of Tumor Suppressor Protein p53
Authors: Rui Kamada
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-4-431-54135-6
Publisher: Springer Tokyo
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Japan 2012
Hardcover ISBN: 978-4-431-54134-9Published: 21 July 2012
Softcover ISBN: 978-4-431-54725-9Published: 09 August 2014
eBook ISBN: 978-4-431-54135-6Published: 20 July 2012
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XIV, 74
Topics: Bioorganic Chemistry, Medicinal Chemistry, Proteomics