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Histiozytosen

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Braun-Falco’s Dermatologie, Venerologie und Allergologie

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Zusammenfassung

Histiozytosen kommen durch eine Ansammlung von dendritischen Zellen oder Makrophagen zustande. 5 Gruppen werden unterschieden: die Langerhans-Zell-Gruppe, kutane und mukokutane Non-Langerhans-Zell-Histiozytosen, maligne Histiozytosen, die Rosai-Dorfman Krankheit und die hämophagozytische Lymphohistiozytose. Die seltenen Langerhans-Zell-Histiozytosen umfassen lokalisierte bis generalisierte sowie selbstlimitierende bis lebensbedrohliche Manifestationen bei Kindern und Erwachsenen. Am häufigsten sind Knochen und Haut betroffen. Den häufigeren, zumeist gutartig verlaufenden Non-Langerhans-Zell-Histiozytosen liegt eine nodulär bis diffuse Makrophagen-dominierte Dermatitis zugrunde. Die Xanthogranulom-Familie betrifft vorwiegend Kinder, meistens kommt es zu Spontanremission. Die weiteren Histiozytosen sind sehr selten. Lebensbedrohlich können die malignen Histiozytosen oder die hämophagozytische Lymphohistiozytose verlaufen.

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Authors and Affiliations

  1. Universitätsklinik für Dermatologie und Venerologie, Medizinische Universität, Anichstr. 35, 6020, Innsbruck, Österreich

    Gudrun Ratzinger & Bernhard Zelger

Authors
  1. Gudrun Ratzinger
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  2. Bernhard Zelger
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Corresponding author

Correspondence to Gudrun Ratzinger .

Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum München, München, Germany

    Gerd Plewig

  2. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum München, München, Germany

    Thomas Ruzicka

  3. Klinik für Dermatologie, Venerologie und Allergologie, J.W.Goethe-Universität, Frankfurt, Germany

    Roland Kaufmann

  4. Klinik für Dermatologie und Allergologie, Universitätsklinikum Marburg, Marburg, Germany

    Michael Hertl

Section Editor information

  1. Direktor der Klinik für Dermatologie, Venerologie und Allergologie, Klinikum der J.W.Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland

    Roland Kaufmann

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Ratzinger, G., Zelger, B. (2018). Histiozytosen. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco’s Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49544-5_112

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  • DOI: https://doi.org/10.1007/978-3-662-49544-5_112

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