Abstract
Sebum produced by sebaceous glands is progressively altered during its transit in the sebaceous duct. Sebaceous gland dynamics involves four successive features including sebum productive and storage, sebum delivery at the skin surface, and the sebum resorption by the stratum corneum. The excretion rate at the skin surface is indeed different from the secretion rate by the gland. The skin microbiome is globally influenced by sebum that promotes anaerobic and lipophilic microorganisms. The lipid composition of sebum exerts profound influences on epithelial tissues.
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References
Grice EA. The skin microbiome: potential for novel diagnostic and therapeutic approaches to cutaneous disease. Semin Cutan Med Surg. 2014;33:98–103.
Jahns AC, et al. Propionibacterium species and follicular keratinocyte activation in acneic and normal skin. Br J Dermatol. 2015;172:981–987.
Porta Guardia CA. Demodex folliculorum: its association with oily skin surface rather than rosacea lesions. Int J Dermatol. 2015;54:e14–7.
Szepetiuk G, et al. Recent trends in specular light reflectance beyond clinical fluorescence diagnosis. Eur J Dermatol. 2011;21:157–61.
Piérard-Franchimont C, et al. Sun addiction, its death blow and the multitude of sunscreens. Rev Med Liege. 2013;68:321–5.
Piérard GE, et al. EEMCO guidance for the in vivo assessment of skin greasiness. The EEMCO Group. Skin Pharmacol Appl Skin Physiol. 2000;13:372–89.
Petit L, et al. Subclinical speckled perifollicular melanosis of the scalp. Eur J Dermatol. 2002;12:565–8.
Uhoda E, et al. The conundrum of skin pores in dermocosmetology. Dermatology. 2005;210:3–7.
Kim SJ, et al. Pore volume is most highly correlated with the visual assessment of skin pores. Skin Res Technol. 2014;20:429–34.
Blanc D, et al. An original procedure for quantitation of cutaneous resorption of sebum. Arch Dermatol Res. 1989;281:346–50.
Piérard-Franchimont C, et al. Sebum rheology evaluated by two methods in vivo. Split-face study of the effect of a cosmetic formulation. Eur J Dermatol. 1999;9:455–7.
Coulson-Thomas VJ, et al. Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis. J Biol Chem. 2014;289:25211–26.
Akaza N, et al. Fatty acid compositions of triglycerides and free fatty acids in sebum depend on amount of triglycerides, and do not differ in presence or absence of acne vulgaris. J Dermatol. 2014;41:1069–76.
Boncheva M. The physical chemistry of the stratum corneum lipids. Int J Cosmet Sci. 2014;36:505–15.
Nordstrom KM, et al. Measurement of sebum output using a lipid absorbent tape. J Invest Dermatol. 1986;87:260–3.
Piérard GE. Follicule to follicule heterogeneity of sebum excretion. Dermatologica. 1986;173:61–5.
Piérard GE. Rate and topography of follicular sebum excretion. Dermatologica. 1987;175:280–3.
Pagnoni A, et al. An improved procedure for quantitative analysis of sebum production using Sebutape. J Soc Cosmet Chem. 1994;45:221–5.
Piérard GE, Piérard-Franchimont C. Effect of a topical erythromycin-zinc formulation on sebum delivery. Evaluation by combined photometric-multi-step samplings with Sebutape. Clin Exp Dermatol. 1993;18:410–3.
Piérard GE, et al. Kinetics of sebum excretion evaluated by the Sebutape – Chromameter technique. Skin Pharmacol. 1993;6:38–44.
Piérard-Franchimont C, Piérard GE. Postmenopausal aging of the sebaceous follicle: a comparison between women receiving hormone replacement therapy or not. Dermatology. 2002;204:17–22.
Piérard GE, et al. Cyanoacrylate skin surface stripping and the 3S-Biokit advent in tropical dermatology: a look from Liege. Sci World J. 2014;2014:462634.
Piérard GE, et al. Digital image analysis of microcomedones. Dermatology. 1995;190:99–103.
El Khyat A, et al. Skin critical surface tension. A way to assess the skin wettability quantitatively. Skin Res Technol. 1996;2:91–6.
Piérard-Franchimont C, et al. Seasonal modulation of sebum excretion. Dermatologica. 1990;181:21–2.
Youn SW, et al. Regional and seasonal variations in facial sebum secretions: a proposal for the definition of combination skin type. Skin Res Technol. 2005;11:189–95.
Song EJ, et al. A study on seasonal variation of skin parameters in Korean males. Int J Cosmet Sci. 2015;37:92–7.
Piérard-Franchimont C, et al. Rhythm of sebum excretion during the menstrual cycle. Dermatologica. 1991;182:211–3.
Verschoore M, et al. Circadian variations in the number of actively secreting sebaceous follicles and androgen circadian rhythms. Chronobiol Int. 1993;10:349–59.
Black D, et al. An improved method for the measurement of scalp sebum. Curr Probl Dermatol. 1998;26:61–8.
Thiboutot D, et al. Activity of the type 1 5 alpha-reductase exhibits regional differences in isolated sebaceous glands and whole skin. J Invest Dermatol. 1995;105:209–14.
Zouboulis CC, et al. The human sebocyte culture model provides new insights into development and management of seborrhoea and acne. Dermatology. 1998;196:21–31.
Rutkowski K, et al. Dehydroepiandrosterone (DHEA): hypes and hopes. Drugs. 2014;74:1195–207.
Rosenfield RL, et al. Mechanisms of androgen induction of sebocyte differentiation. Dermatology. 1998;196:43–6.
Martignoni E, et al. Is seborrhea a sign of autonomic impairment in Parkinson’s disease? J Neural Transm. 1997;104:1295–304.
Nouveau-Richard S, et al. Oily skin: specific features in Chinese women. Skin Res Technol. 2007;13:43–8.
Piérard GE, et al. Patterns of follicular sebum excretion rate during lifetime. Arch Dermatol Res. 1987;279(Suppl):S104–7.
Callens A, et al. Does hormonal skin aging exist? A study of the influence of different hormone therapy regimens on the skin of postmenopausal women using non-invasive measurement techniques. Dermatology. 1996;193:289–94.
Caisey L, et al. Influence of age and hormone replacement therapy on the functional properties of the lips. Skin Res Technol. 2008;14:220–5.
Piérard GE, Cauwenbergh G. Modulation of sebum excretion from the follicular reservoir by a dichlorophenyl-imidazoldioxolan. Int J Cosmet Sci. 1996;18:219–27.
Piérard GE, et al. New insight into the topical management of excessive sebum flow at the skin surface. Dermatology. 1998;196:126–9.
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Piérard-Franchimont, C., Lesuisse, M., Courtois, J., Ritacco, C., Piérard, G.E. (2017). Sebum Production. In: Farage, M., Miller, K., Maibach, H. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47398-6_33
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DOI: https://doi.org/10.1007/978-3-662-47398-6_33
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