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Immunodeficiency Syndromes and Atopic Eczema

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Handbook of Atopic Eczema

Abstract

“Eczemas” are a not infrequently associated symptom of primary immunodeficiencies (PID). Morphologically, these dermatitic lesions are of varied appearance, often fairly indistinctive and difficult to classify. They have been referred to as “eczematoid”, “nummular”, “seborrhoeic”, “resembling atopic eczema” or atopic eczema (AE). This latter point has aroused considerable interest in the past few decades because of the known abnormalities of the humoral and cell-mediated immune system in AE. If some PID are indeed linked to unequivocal AE — a question far from trivial — they might provide useful clues to the pathogenesis of AE. Only recently, Saurat et al. [43, 44, 45] reviewed this subject. They were the first to apply the clinical criteria of AE as formulated by Hanifin and Rajka [16] to the eczemas of PID: Wiskott-Aldrich syndrome met these criteria, but for other PID the evidence was incomplete at best or unconvincing.

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Authors
  1. P. Fritsch
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  2. H. Hintner
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Editors and Affiliations

  1. Dermatologische Klinik und Poliklinik, Universität München, Frauenlobstr. 9-11, 8000, München 2, Germany

    Thomas Ruzicka  & Bernhard Przybilla  & 

  2. Hautklinik, Universitätskrankenhaus Eppendorf, Martinistr. 52, 2000, Hamburg 20, Germany

    Johannes Ring

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© 1991 Springer-Verlag Berlin Heidelberg

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Fritsch, P., Hintner, H. (1991). Immunodeficiency Syndromes and Atopic Eczema. In: Ruzicka, T., Ring, J., Przybilla, B. (eds) Handbook of Atopic Eczema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02671-7_12

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  • DOI: https://doi.org/10.1007/978-3-662-02671-7_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-02673-1

  • Online ISBN: 978-3-662-02671-7

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