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Fractionated Afterloading Therapy in the Treatment of Malignant, Inoperable Brain Tumors

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Interventional Radiation Therapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Due to postoperative radiotherapy, the mean survival period of patients with malignant gliomas has been raised from 4.5 to 10.5 months (Walker et al. 1979). A combination of most thorough surgical removal of the tumor and postoperative radiotherapy (Jelsma and Bucy 1967; Sheline 1977) has become a generally recognized therapy concept. No long-term, statistically significant increase in the survival period could be achieved by raising the target dose from 60 to 80 Gy (Salazar et al. 1979), and this notion was abandoned in view of the possibility of complications (radionecroses) (Chin et al. 1986).

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Authors and Affiliations

  1. Abteilung Radiologie und Strahlentherapie, Germany

    Anne Sparenberg (Dr. med.) & Helmut Ernst (Prof. Dr. med.)

  2. Abteilung Neurochirurgie, Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, 1000, Berlin 45, Germany

    Klaus Weigel (Dr. med.)

Authors
  1. Anne Sparenberg
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  2. Klaus Weigel
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  3. Helmut Ernst
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Editor information

Editors and Affiliations

  1. Strahlentherapeutische Universitätsklinik, Universität Erlangen-Nürnberg, Universitätsstr. 27, 8520, Erlangen, Germany

    Rolf Sauer

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© 1991 Springer-Verlag Berlin Heidelberg

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Sparenberg, A., Weigel, K., Ernst, H. (1991). Fractionated Afterloading Therapy in the Treatment of Malignant, Inoperable Brain Tumors. In: Sauer, R. (eds) Interventional Radiation Therapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84163-7_9

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  • DOI: https://doi.org/10.1007/978-3-642-84163-7_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84165-1

  • Online ISBN: 978-3-642-84163-7

  • eBook Packages: Springer Book Archive

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