Nomenclature
EC number
4.2.3.39
Systematic name
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming)
Recommended name
epi-cedrol synthase
Synonyms
8-epicedrol synthase <2> [1,4]
epicedrol synthase
sesquiterpene cyclase <1> [2]
CAS registry number
251113-52-7
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References
Hua, L.; Matsuda, S.P.: The molecular cloning of 8-epicedrol synthase from Artemisia annua. Arch. Biochem. Biophys., 369, 208-212 (1999)
Mercke, P.; Crock, J.; Croteau, R.; Brodelius, P.E.: Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L. Arch. Biochem. Biophys., 369, 213-222 (1999)
Jackson, B.E.; Hart-Wells, E.A.; Matsuda, S.P.: Metabolic engineering to produce sesquiterpenes in yeast. Org. Lett., 5, 1629-1632 (2003)
Feng, L.; Yang, R.; Yang, X.; Zeng, X.; Lu, W.; Zeng, Q.: Synergistic re-channeling of mevalonate pathway for enhanced artemisinin production in transgenic Artemisia annua. Plant Sci., 177, 57-67 (2009)
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Schomburg, D., Schomburg, I. (2013). epi-cedrol synthase 4.2.3.39. In: Schomburg, D., Schomburg, I. (eds) Class 3.4–6 Hydrolases, Lyases, Isomerases, Ligases. Springer Handbook of Enzymes, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36260-6_60
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