Nomenclature
EC number
3.1.3.78
Systematic name
1-phosphatidyl-1d-myo-inositol-4,5-bisphosphate 4-phosphohydrolase
Recommended name
phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Synonyms
IpgD <6> [5]
PtdIns-4,5-P2 4-phosphatase type I
PtdIns-4,5-P2 4-phosphatase type II
SigD <1,3,7> [2,4,6]
phosphatidylinositol-4,5-bisphosphate 4-phosphatase I <4> [1]
phosphatidylinositol-4,5-bisphosphate 4-phosphatase II <5> [1]
phosphoinositide phosphatase <1> [4]
type I 4-phosphatase <2> [3]
type I PtdIns-4,5-P2 4-Ptase <4> [1]
type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase <2> [3]
type II 4-phosphatase <2> [3]
type II PtdIns-4,5-P2 4-Ptase <5> [1]
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References
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Niebuhr, K.; Giuriato, S.; Pedron, T.; Philpott, D.J.; Gaits, F.; Sable, J.; Sheetz, M.P.; Parsot, C.; Sansonetti, P.J.; Payrastre, B.: Conversion of PtdIns(4,5)P2 into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology. EMBO J., 21, 5069-5078 (2002)
Terebiznik, M.R.; Vieira, O.V.; Marcus, S.L.; Slade, A.; Yip, C.M.; Trimble, W.S.; Meyer, T.; Finlay, B.B.; Grinstein, S.: Elimination of host cell PtdIns(4,5)P2 by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat. Cell Biol., 4, 766-773 (2002)
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Schomburg, D., Schomburg, I. (2013). phosphatidylinositol-4,5-bisphosphate 4-phosphatase 3.1.3.78. In: Schomburg, D., Schomburg, I. (eds) Class 2–3.2 Transferases, Hydrolases. Springer Handbook of Enzymes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36240-8_108
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