Abstract
Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) is a periodic fever syndrome in children. The etiology is unknown, and the course is usually self-limited taking 3–5 years to resolve. Treatment options include watchful waiting, medical management in the form of episodic oral steroids (for each episode which are very effective) or H2 blockers (which are used prophylactically and resolve the syndrome in less than 25 % of patients), or surgical management in the form of tonsillectomy (which resolve the syndrome in greater than 90 % of patients).
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Kavanagh, K.R., Feder, H.M. (2016). PFAPA: Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis. In: Valdez, T., Vallejo, J. (eds) Infectious Diseases in Pediatric Otolaryngology. Springer, Cham. https://doi.org/10.1007/978-3-319-21744-4_16
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DOI: https://doi.org/10.1007/978-3-319-21744-4_16
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