Abstract
Wireless capsule endoscopy (WCE) is a painless and non-invasive diagnostic tool for gastrointestinal (GI) diseases. However, due to GI anatomical constraints and hardware manufacturing limitations, WCE vision signals may suffer from insufficient illumination, leading to a complicated screening and examination procedure. Deep learning-based low-light image enhancement (LLIE) in the medical field gradually attracts researchers. Given the exuberant development of the denoising diffusion probabilistic model (DDPM) in computer vision, we introduce a WCE LLIE framework based on the multi-scale convolutional neural network (CNN) and reverse diffusion process. The multi-scale design allows models to preserve high-resolution representation and context information from low-resolution, while the curved wavelet attention (CWA) block is proposed for high-frequency and local feature learning. Moreover, we combine the reverse diffusion procedure to optimize the shallow output further and generate images highly approximate to real ones. The proposed method is compared with eleven state-of-the-art (SOTA) LLIE methods and significantly outperforms quantitatively and qualitatively. The superior performance on GI disease segmentation further demonstrates the clinical potential of our proposed model. Our code is publicly accessible at github.com/longbai1006/LLCaps.
L. Bai and T. Chen—are co-first authors.
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References
Charbonnier, P., Blanc-Feraud, L., Aubert, G., Barlaud, M.: Two deterministic half-quadratic regularization algorithms for computed imaging. In: Proceedings of 1st International Conference on Image Processing, vol. 2, pp. 168–172. IEEE (1994)
Chen, W., Liu, Y., Hu, J., Yuan, Y.: Dynamic depth-aware network for endoscopy super-resolution. IEEE J. Biomed. Health Inform. 26(10), 5189–5200 (2022)
Coelho, P., Pereira, A., Leite, A., Salgado, M., Cunha, A.: A deep learning approach for red lesions detection in video capsule endoscopies. In: Campilho, A., Karray, F., ter Haar Romeny, B. (eds.) ICIAR 2018. LNCS, vol. 10882, pp. 553–561. Springer, Cham (2018). https://doi.org/10.1007/978-3-319-93000-8_63
Fan, C.M., Liu, T.J., Liu, K.H.: Half wavelet attention on M-Net+ for low-light image enhancement. In: 2022 IEEE International Conference on Image Processing (ICIP), pp. 3878–3882. IEEE (2022)
Gómez, P., Semmler, M., Schützenberger, A., Bohr, C., Döllinger, M.: Low-light image enhancement of high-speed endoscopic videos using a convolutional neural network. Med. Biol. Eng. Comput. 57(7), 1451–1463 (2019). https://doi.org/10.1007/s11517-019-01965-4
Guo, C., et al.: Zero-reference deep curve estimation for low-light image enhancement. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 1780–1789 (2020)
Guo, X., Li, Y., Ling, H.: LIME: low-light image enhancement via illumination map estimation. IEEE Trans. Image Process. 26(2), 982–993 (2016)
Ho, J., Jain, A., Abbeel, P.: Denoising diffusion probabilistic models. Adv. Neural. Inf. Process. Syst. 33, 6840–6851 (2020)
Huynh-Thu, Q., Ghanbari, M.: Scope of validity of PSNR in image/video quality assessment. Electron. Lett. 44(13), 800–801 (2008)
Jiang, Y., et al.: EnlightenGAN: deep light enhancement without paired supervision. IEEE Trans. Image Process. 30, 2340–2349 (2021)
Li, C., et al.: Low-light image and video enhancement using deep learning: a survey. IEEE Trans. Pattern Anal. Mach. Intell. 44(12), 9396–9416 (2021)
Li, J., Fang, F., Mei, K., Zhang, G.: Multi-scale residual network for image super-resolution. In: Proceedings of the European Conference on Computer Vision (ECCV), pp. 517–532 (2018)
Li, M., Liu, J., Yang, W., Sun, X., Guo, Z.: Structure-revealing low-light image enhancement via robust retinex model. IEEE Trans. Image Process. 27(6), 2828–2841 (2018)
Liu, Y.F., Guo, J.M., Yu, J.C.: Contrast enhancement using stratified parametric-oriented histogram equalization. IEEE Trans. Circuits Syst. Video Technol. 27(6), 1171–1181 (2016)
Long, M., Li, Z., Xie, X., Li, G., Wang, Z.: Adaptive image enhancement based on guide image and fraction-power transformation for wireless capsule endoscopy. IEEE Trans. Biomed. Circuits Syst. 12(5), 993–1003 (2018)
Lore, K.G., Akintayo, A., Sarkar, S.: LLNet: a deep autoencoder approach to natural low-light image enhancement. Pattern Recogn. 61, 650–662 (2017)
Ma, Y., et al.: Structure and illumination constrained GAN for medical image enhancement. IEEE Trans. Med. Imaging 40(12), 3955–3967 (2021)
Ma, Y., et al.: Cycle structure and illumination constrained GAN for medical image enhancement. In: Martel, A.L., et al. (eds.) MICCAI 2020, Part II. LNCS, vol. 12262, pp. 667–677. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-59713-9_64
Pandey, K., Mukherjee, A., Rai, P., Kumar, A.: DiffuseVAE: efficient, controllable and high-fidelity generation from low-dimensional latents. arXiv preprint arXiv:2201.00308 (2022)
Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015, Part III. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Sliker, L.J., Ciuti, G.: Flexible and capsule endoscopy for screening, diagnosis and treatment. Expert Rev. Med. Devices 11(6), 649–666 (2014)
Smedsrud, P.H., et al.: Kvasir-capsule, a video capsule endoscopy dataset. Sci. Data 8(1), 142 (2021)
Venkatanath, N., Praneeth, D., Bh, M.C., Channappayya, S.S., Medasani, S.S.: Blind image quality evaluation using perception based features. In: 2015 Twenty First National Conference on Communications (NCC), pp. 1–6. IEEE (2015)
Wang, Y., Wan, R., Yang, W., Li, H., Chau, L.P., Kot, A.: Low-light image enhancement with normalizing flow. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 36, pp. 2604–2612 (2022)
Wang, Z., Bovik, A.C., Sheikh, H.R., Simoncelli, E.P.: Image quality assessment: from error visibility to structural similarity. IEEE Trans. Image Process. 13(4), 600–612 (2004)
Wu, J., Fu, R., Fang, H., Zhang, Y., Xu, Y.: MedSegDiff-V2: diffusion based medical image segmentation with transformer. arXiv preprint arXiv:2301.11798 (2023)
Xiao, T., Singh, M., Mintun, E., Darrell, T., Dollár, P., Girshick, R.: Early convolutions help transformers see better. Adv. Neural. Inf. Process. Syst. 34, 30392–30400 (2021)
Xu, X., Wang, R., Fu, C.W., Jia, J.: SNR-aware low-light image enhancement. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 17714–17724 (2022)
Zamir, S.W., et al.: Learning enriched features for real image restoration and enhancement. In: Vedaldi, A., Bischof, H., Brox, T., Frahm, J.-M. (eds.) ECCV 2020, Part XXV. LNCS, vol. 12370, pp. 492–511. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-58595-2_30
Zamir, S.W., et al.: Learning enriched features for fast image restoration and enhancement. IEEE Trans. Pattern Anal. Mach. Intell. 45(2), 1934–1948 (2022)
Zhang, Q., Nie, Y., Zheng, W.S.: Dual illumination estimation for robust exposure correction. In: Computer Graphics Forum, vol. 38, pp. 243–252 (2019)
Zhang, R., Isola, P., Efros, A.A., Shechtman, E., Wang, O.: The unreasonable effectiveness of deep features as a perceptual metric. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 586–595 (2018)
Zhou, S., Li, C., Change Loy, C.: LEDNet: joint low-light enhancement and deblurring in the dark. In: Avidan, S., Brostow, G., Cissé, M., Farinella, G.M., Hassner, T. (eds.) ECCV 2022. LNCS, vol. 13666, pp. 573–589. Springer, Cham (2022). https://doi.org/10.1007/978-3-031-20068-7_33
Acknowledgements
This work was supported by Hong Kong RGC CRF C4063-18G, CRF C4026-21GF, RIF R4020-22, GRF 14216022, GRF 14211420, NSFC/RGC JRS N_CUHK420/22; Shenzhen-Hong Kong-Macau Technology Research Programme (Type C 202108233000303); GBABF #2021B1515120035.
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Bai, L., Chen, T., Wu, Y., Wang, A., Islam, M., Ren, H. (2023). LLCaps: Learning to Illuminate Low-Light Capsule Endoscopy with Curved Wavelet Attention and Reverse Diffusion. In: Greenspan, H., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023. MICCAI 2023. Lecture Notes in Computer Science, vol 14229. Springer, Cham. https://doi.org/10.1007/978-3-031-43999-5_4
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