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Genetics in Unusual Facial Clefts

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Facial Reconstruction of Unusual Facial Clefts

Abstract

There are thousands of rare diseases in aggregate affecting millions of people worldwide. Among those, rare forms of clefts are included. These unusual cleft cases are sporadic and likely due to significant gene effects. This chapter discusses the modes of inheritance of rare diseases in general and rare forms of clefts. It raises concerns regarding the clinical practice of genetic counseling and ethical issues of increasing demand for whole genome sequencing.

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Author information

Authors and Affiliations

  1. School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA

    Alexandre R. Vieira

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  1. Alexandre R. Vieira
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Correspondence to Alexandre R. Vieira .

Editor information

Editors and Affiliations

  1. Department of Plastic Surgery, Universidade de São Paulo, São Paulo, São Paulo, Brazil

    Nivaldo Alonso

  2. Plastic Surgery Unit, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Brazil

    Renato da Silva Freitas

  3. Craniofacial Surgery Department, Universidade de São Paulo, Bauru, São Paulo, Brazil

    Cristiano Tonello

  4. Plastic Surgery Department, University of Lille, Lambersart, France

    Philippe Pellerin

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© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Vieira, A.R. (2023). Genetics in Unusual Facial Clefts. In: Alonso, N., Freitas, R.d.S., Tonello, C., Pellerin, P. (eds) Facial Reconstruction of Unusual Facial Clefts. Springer, Cham. https://doi.org/10.1007/978-3-031-40926-4_2

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  • DOI: https://doi.org/10.1007/978-3-031-40926-4_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-40925-7

  • Online ISBN: 978-3-031-40926-4

  • eBook Packages: MedicineMedicine (R0)

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