Abstract
Ripening of fruit is a complex physiological process comprising a sequence of events that precipitates the signaling molecules, especially hydrogen peroxide (H2O2), ethylene, melatonin, nitric oxide (NO), auxin, hydrogen sulfide (H2S), and brassinosteroids at different levels of gene and protein expression to initiate activation and/or deactivation of various signaling pathways that ultimately lead to the ripening of the fruit. Although ethylene has been documented as a potent molecule capable of regulating fruit ripening, molecules such as phytomelatonin, NO, H2O2, and H2S have the potential of regulating fruit ripening. However, the interaction of ethylene and these new emerging signaling molecules particularly phytomelatonin, NO, H2O2, and H2S is not fully understood. Therefore, harnessing the phytohormonal functions of phytomelatonin in fruit ripening physiology via crosstalk with ethylene and NO as well as H2O2 and H2S is of biological importance in revealing the free radical scavenging role of phytomelatonin. In this chapter, the interaction of melatonin in fruit ripening in an ethylene-NO- H2O2-H2S -dependent manner via the various signaling pathways will be highlighted and presented.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Abdel-Mohsein H, Yamamoto N, Otawa K, Tada C, Nakai Y (2010) Isolation of bacteriocin-like substances producing bacteria from finished cattle-manure compost and activity evaluation against some food-borne pathogenic and spoilage bacteria. J Gen Appl Microbiol 56(2):151–161. https://doi.org/10.2323/jgam.56.151
Adams-Phillips L, Barry C, Giovannoni J (2004) Signal transduction systems regulating fruit ripening. Trends Plant Sci 9(7):331–338. https://doi.org/10.1016/j.tplants.2004.05.004
Akhtar N, Wani AK, Dhanjal DS, Mukherjee S (2022) Insights into the beneficial roles of dark septate endophytes in plants under challenging environment: resilience to biotic and abiotic stresses. World J Microbiol Biotechnol 38(5):79. https://doi.org/10.1007/s11274-022-03264-x
Arnao MB (2014) Phytomelatonin: discovery, content, and role in plants. Adv Bot 2014:1–11. https://doi.org/10.1155/2014/815769
Arnao MB, Hernández-Ruiz J (2019) Melatonin as a chemical substance or as phytomelatonin rich-extracts for use as plant protector and/or biostimulant in accordance with EC legislation. Agronomy 9(10). https://doi.org/10.3390/agronomy9100570
Basheer M, Rai S (2016) Melatonin vs. phytomelatonin: therapeutic uses with special reference to polycystic ovarian syndrome (PCOS). Cogent Biol 2(1):1136257. https://doi.org/10.1080/23312025.2015.1136257
Černý M, Habánová H, Berka M, Luklová M, Brzobohatý B (2018) Hydrogen peroxide: its role in plant biology and crosstalk with signalling networks. Int J Mol Sci 19(9). https://doi.org/10.3390/ijms19092812
Corpas FJ, Rodríguez-Ruiz M, Muñoz-Vargas MA, González-Gordo S, Reiter RJ, Palma JM (2022) Interactions of melatonin, reactive oxygen species, and nitric oxide during fruit ripening: an update and prospective view. J Exp Bot 73:5947–5960. https://doi.org/10.1093/jxb/erac128
Dubbels R, Reiter RJ, Klenke E, Goebel A, Schnakenberg E, Ehlers C, Schiwara HW, Schloot W (1995) Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography-mass spectrometry. J Pineal Res 18(1):28–31. https://doi.org/10.1111/j.1600-079X.1995.tb00136.x
Giovannoni JJ (2004) Genetic regulation of fruit development and ripening. Plant Cell 16(SUPPL):170–180. https://doi.org/10.1105/tpc.019158
Giovannoni JJ (2007) Fruit ripening mutants yield insights into ripening control. Curr Opin Plant Biol 10(3):283–289. https://doi.org/10.1016/j.pbi.2007.04.008
Hardeland R (2009) Melatonin: signaling mechanisms of a pleiotropic agent. Biofactors 35(2):183–192. https://doi.org/10.1002/biof.23
Hardeland R, Balzer I, Poeggeler B, Fuhrberg B, Una H, Behrmann G, Wolf R, Meyer TJ, Reiter RJ (1995) On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals. J Pineal Res 18(2):104–111. https://doi.org/10.1111/j.1600-079X.1995.tb00147.x
Hardeland R, Pandi-Perumal SR, Cardinali DP (2006) Melatonin. Int J Biochem Cell Biol 38(3):313–316. https://doi.org/10.1016/j.biocel.2005.08.020
Houben M, Van de Poel B (2019) 1-aminocyclopropane-1-carboxylic acid oxidase (ACO): the enzyme that makes the plant hormone ethylene. Front Plant Sci 10(May):1–15. https://doi.org/10.3389/fpls.2019.00695
Khanna K, Sharma N, Kour S, Mohd A, Ohri P, Bhardwaj R (2021) Hydrogen sulfide: a robust combatant against abiotic stresses in plants. Hydrogen 2(3):319–342. https://doi.org/10.3390/hydrogen2030017
Lerner A et al (1958) Isolation of melatonin, pineal factor that lightens melanocytes. J Am Chem Soc 80(2):2587
Liu S, Huang H, Huber DJ, Pan Y, Shi X, Zhang Z (2020) Delay of ripening and softening in ‘Guifei’ mango fruit by postharvest application of melatonin. Postharvest Biol Technol 163(November 2019):111136. https://doi.org/10.1016/j.postharvbio.2020.111136
Liu Y, Wang X, Lv H, Cao M, Li Y, Yuan X, Zhang X, Guo Y-D, Zhang N (2022) Anabolism and signaling pathways of phytomelatonin. J Exp Bot 73:5801–5817. https://doi.org/10.1093/jxb/erac158
Losada M, Cano A, Hernández-Ruiz J, Arnao MB (2022) Phytomelatonin content in Valeriana officinalis L. and some related phytotherapeutic supplements. Int J Plant Based Pharm 2:176–181. https://doi.org/10.55484/ijpbp.1079005
Mannino G, Pernici C, Serio G, Gentile C, Bertea CM (2021) Melatonin and phytomelatonin: chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—an overview. Int J Mol Sci 22(18). https://doi.org/10.3390/ijms22189996
Mir TUG, Wani AK, Akhtar N, Shukla S (2022) CRISPR/Cas9: regulations and challenges for law enforcement to combat its dual-use. Forensic Sci Int 334:111274. https://doi.org/10.1016/j.forsciint.2022.111274
Moustafa-Farag M, Almoneafy A, Mahmoud A, Elkelish A, Arnao MB, Li L, Ai S (2020) Melatonin and its protective role against biotic stress impacts on plants. Biomol Ther 10(1):1–12. https://doi.org/10.3390/biom10010054
Mukherjee S (2019) Recent advancements in the mechanism of nitric oxide signaling associated with hydrogen sulfide and melatonin crosstalk during ethylene-induced fruit ripening in plants. Nitric Oxide-Biol Chem 82(September 2018):25–34. https://doi.org/10.1016/j.niox.2018.11.003
Pardo-Hernández M, López-Delacalle M, Rivero RM (2020) ROS and NO regulation by melatonin under abiotic stress in plants. Antioxidants 9(11):1–23. https://doi.org/10.3390/antiox9111078
Pöggeler B, Balzer I, Hardeland R, Lerchl A (1991) Pineal hormone melatonin oscillates also in the dinoflagellate Gonyaulax polyedra. Naturwissenschaften 78(6):268–269. https://doi.org/10.1007/BF01134354
Reiter RJ (2003) Melatonin: Clinical relevance. Best Pract Res Clin Endocrinol Metab 17(2):273–285. https://doi.org/10.1016/S1521-690X(03)00016-2
Rodríguez-Ruiz M, Zuccarelli R, Palma JM, Corpas FJ, Freschi L (2019) Biotechnological application of nitric oxide and hydrogen peroxide in plants. In: Nitric oxide hydrogen peroxide signaling in higher plants. Springer, pp 245–270. https://doi.org/10.1007/978-3-030-11129-8_12
Sharif Usman S, Dahiru M, Abdullahi B, Abdullahi SB, Maigari UM, Ibrahim Uba A (2019) Status of malondialdehyde, catalase and superoxide dismutase levels/activities in schoolchildren with iron deficiency and iron-deficiency anemia of Kashere and its environs in Gombe state, Nigeria. Heliyon 5(8):e02214. https://doi.org/10.1016/j.heliyon.2019.e02214
Steelheart C, Alegre ML, Baldet P, Rothan C, Bres C, Just D, Okabe Y, Ezura H, Ganganelli IM, Gergoff Grozeff GE, Bartoli CG (2022) High light stress induces H2O2 production and accelerates fruit ripening in tomato. Plant Sci 322(February):111348. https://doi.org/10.1016/j.plantsci.2022.111348
Sun Q, Zhang N, Wang J, Zhang H, Li D, Shi J, Li R, Weeda S, Zhao B, Ren S, Guo YD (2015) Melatonin promotes ripening and improves quality of tomato fruit during postharvest life. J Exp Bot 66(3):657–668. https://doi.org/10.1093/jxb/eru332
Sun Q, Liu L, Zhang L, Lv H, He Q, Guo L, Zhang X, He H, Ren S, Zhang N, Zhao B, Guo YD (2020) Melatonin promotes carotenoid biosynthesis in an ethylene-dependent manner in tomato fruits. Plant Sci 298:110580. https://doi.org/10.1016/j.plantsci.2020.110580
Turk H, Erdal S, Genisel M, Atici O, Demir Y, Yanmis D (2014) The regulatory effect of melatonin on physiological, biochemical and molecular parameters in cold-stressed wheat seedlings. Plant Growth Regul 74(2):139–152. https://doi.org/10.1007/s10725-014-9905-0
Umeh SO (2017) Effect of microorganisms and storage environments on ripening and Spoilage of Plantain (Musa paradisiaca) fruits sold in Eke Awka market. Int J Peer Rev J Refereed J Index J UGC Approv J Impact Factor 3(10):186–190
Usman SS, Uba AI, Yunusa I, Sadiq Y (2015) Huzaifa U S-nitrosylation in sporadic Parkinson’s disease and cancer (brain and thyroid) prevention. Ann Exp Biol 1:13–19
Vivien-Roels B, Pévet P (1993) Melatonin: presence and formation in invertebrates. Experientia 49(8):642–647. https://doi.org/10.1007/BF01923945
Wani AK, Akhtar N, Datta B, Pandey J, Amin-ul Mannan M (2021) Chapter 14 – cyanobacteria-derived small molecules: a new class of drugs. In: Kumar A, Singh J, Samuel J (eds) Volatiles and metabolites of microbes. Academic, pp 283–303
Wani AK, Akhtar N, Sher F, Navarrete AA, Américo-Pinheiro JHP (2022a) Microbial adaptation to different environmental conditions: molecular perspective of evolved genetic and cellular systems. Arch Microbiol 204(2):144. https://doi.org/10.1007/s00203-022-02757-5
Wani AK, Akhtar N, Singh R, Chopra C, Kakade P, Borde M, Al-Khayri JM, Suprasanna P, Zimare SB (2022b) Prospects of advanced metagenomics and meta-omics in the investigation of phytomicrobiome to forecast beneficial and pathogenic response. Mol Biol Rep 49:12165–12179. https://doi.org/10.1007/s11033-022-07936-7
Wani AK, Akhtar N, Singh R, Prakash A, Raza SHA, Cavalu S, Chopra C, Madkour M, Elolimy A, Hashem NM (2022c) Genome centric engineering using ZFNs, TALENs and CRISPR-Cas9 systems for trait improvement and disease control in animals. Vet Res Commun 47:1–16
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Usman, S.S., Wani, A.K., Uba, A.I., Mir, T.u.G., Mahayu, W.M., Parnidi (2023). Melatonin and Fruit Ripening Physiology: Crosstalk with Ethylene, Nitric Oxide, Hydrogen Peroxide and Hydrogen Sulphide. In: Mukherjee, S., Corpas, F.J. (eds) Melatonin: Role in Plant Signaling, Growth and Stress Tolerance. Plant in Challenging Environments, vol 4. Springer, Cham. https://doi.org/10.1007/978-3-031-40173-2_8
Download citation
DOI: https://doi.org/10.1007/978-3-031-40173-2_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-40172-5
Online ISBN: 978-3-031-40173-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)