Skip to main content

Models of Noninvasive Ventilation Organization in Bioterrorism and Other Catastrophic Conditions

  • Chapter
  • First Online:
Noninvasive Ventilation Outside Intensive Care Unit

Part of the book series: Noninvasive Ventilation. The Essentials ((NVE))

  • 145 Accesses

Abstract

There are different forms of terrorism in the world. However, bioterrorism has the potential to be more devastating than chemical and nuclear terror. The deliberate release of a biological agent into a civilian population, exposing hundreds and thousands of people to a severe pathogen, is called bioterrorism. Bioterrorism may be suspected when unusually high rates of a single disease are seen, or an unusual pathogen is isolated in the laboratory. Millions of people are affected by bioterrorism events and wars. Hospitals and health personnel need to be prepared to deal with thousands of critically ill patients in these cases. Positive pressure mechanical ventilation is required for patients who cannot achieve adequate oxygenation with only oxygen support and develop respiratory failure with high carbon dioxide levels and acidosis during serious epidemics and wars. Positive pressure ventilation is given to patients in two ways; invasive and noninvasive. Noninvasive mechanical ventilation (NIMV) can be preferred primarily in patients who are hemodynamically stable, conscious, and do not have upper airway obstruction with acute respiratory failure and for patients after extubation.

The purpose of NIMV is to reduce intubation rates and to accompany complications.

The risk of scattering microorganisms that cause droplet transmission is high due to positive airway pressure and leaks. These patients should be followed up in negative pressure rooms, and the health-care personnel must provide complete personal protection. Helmet NIMV seems to be more appropriate for these patients due to the leakage risk. In addition, transmission is less, and patients can tolerate it better.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

ARDS:

Acute respiratory distress syndrome

CDC:

Centers for Disease Control

CPAP:

Continuous positive airway pressure

DIC:

Disseminated intravascular coagulation

FDA:

Food and Drug Administration

ICU:

Intensive Care Unit

NIMV:

Noninvasive Mechanical Ventilation

PEEP:

Positive End-Expiratory Pressure

References

  1. Eitzen E, Takafuji E. Textbook of military medicine 2013. Chapter 18 Historical overview of biological warfare. p. 417.

    Google Scholar 

  2. Stephens RS, Wiener CM, Rubinson L. Bioterrorism, and the intensive care unit. Clin Crit Care Med. 2006;1:685–95.

    Article  Google Scholar 

  3. Chung S, Baum CR, Nyquist AC, Disaster preparedness advisory council COEHCOID. Chemical-biological terrorism and its impact on children. Pediatrics. 2020;145(2):e20193749.

    Article  PubMed  Google Scholar 

  4. Centers for Disease Control and Prevention. Bioterrorism Agents/Diseases bChecgaa-caAoS, 2012.

    Google Scholar 

  5. Adalja AA, Toner E, Inglesby TV. Clinical management of potential bioterrorism-related conditions. N Engl J Med. 2015;372(10):954–62.

    Article  CAS  PubMed  Google Scholar 

  6. Sandrock C, Stollenwerk N. Acute febrile respiratory illness in the ICU: reducing disease transmission. Chest. 2008;133(5):1221–31.

    Article  PubMed  Google Scholar 

  7. Bauer TT, Ewig S, Rodloff AC, Muller EE. Acute respiratory distress syndrome and pneumonia: a comprehensive review of clinical data. Clin Infect Dis. 2006;43(6):748–56.

    Article  PubMed  Google Scholar 

  8. Hui DS, Hall SD, Chan MT, Chow BK, Tsou JY, Joynt GM, et al. Non-invasive positive-pressure ventilation: an experimental model to assess air and particle dispersion. Chest. 2006;130(3):730–40.

    Article  PubMed  Google Scholar 

  9. World Health Organization. The global eradication of smallpox: final report of the global commission for the certification of smallpox eradication. Geneva: World Health Organization; 1980.

    Google Scholar 

  10. Sandrock C. Bioterrorism. Murray and Nadel’s textbook of respiratory medicine 2016:699–712.e2.

    Google Scholar 

  11. Inglesby TV, Henderson DA, Bartlett JG, Ascher MS, Eitzen E, Friedlander AM, et al. Anthrax as a biological weapon: medical and public health management. Working Group on Civilian Biodefense. JAMA. 1999;281(18):1735–45.

    Article  CAS  PubMed  Google Scholar 

  12. Goldman DL, Casadevall A. Anthrax-associated shock. Front Biosci. 2008;13:4009–14.

    CAS  PubMed  Google Scholar 

  13. Cuneo BM. Inhalational anthrax. Respir Care Clin N Am. 2004;10(1):75–82.

    Article  PubMed  Google Scholar 

  14. Borio L, Frank D, Mani V, Chiriboga C, Pollanen M, Ripple M, et al. Death due to bioterrorism-related inhalational anthrax: report of 2 patients. JAMA. 2001;286(20):2554–9.

    Article  CAS  PubMed  Google Scholar 

  15. Noseworthy TW, Anderson, B.J. Massive hemoptysis 1986.

    Google Scholar 

  16. Centers for Disease C, Prevention. Human plague—United States, 1993–1994. MMWR Morb Mortal Wkly Rep. 1994;43(13):242–6.

    Google Scholar 

  17. Warren R, Lockman H, Barnewall R, Krile R, Blanco OB, Vasconcelos D, et al. Cynomolgus macaque model for pneumonic plague. Microb Pathog. 2011;50(1):12–22.

    Article  CAS  PubMed  Google Scholar 

  18. Prentice MB, Rahalison L. Plague. Lancet. 2007;369(9568):1196–207.

    Article  PubMed  Google Scholar 

  19. Crook LD, Tempest B. Plague. A clinical review of 27 cases. Arch Intern Med. 1992;152(6):1253–6.

    Article  CAS  PubMed  Google Scholar 

  20. Wang H, Cui Y, Wang Z, Wang X, Guo Z, Yan Y, et al. A dog-associated primary pneumonic plague in Qinghai Province, China. Clin Infect Dis. 2011;52(2):185–90.

    Article  PubMed  Google Scholar 

  21. Ratsitorahina M, Chanteau S, Rahalison L, Ratsifasoamanana L, Boisier P. Epidemiological and diagnostic aspects of the outbreak of pneumonic plague in Madagascar. Lancet. 2000;355(9198):111–3.

    Article  CAS  PubMed  Google Scholar 

  22. Loskutov OA, Pylypenko MM. The courage of Ukrainian hospitals and intensive care units in the first months of the Russia-Ukraine war. Intensive Care Med. 2022;48:790.

    Article  PubMed  Google Scholar 

  23. Smith DL, Cairns BA, Ramadan F, Dalston JS, Fakhry SM, Rutledge R, et al. Effect of inhalation injury, burn size, and age on mortality: a study of 1447 consecutive burn patients. J Trauma. 1994;37(4):655–9.

    Article  CAS  PubMed  Google Scholar 

  24. Shirani KZ, Pruitt BA Jr, Mason AD Jr. The influence of inhalation injury and pneumonia on burn mortality. Ann Surg. 1987;205(1):82–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Girou E, Schortgen F, Delclaux C, Brun-Buisson C, Blot F, Lefort Y, et al. Association of non-invasive ventilation with nosocomial infections and survival in critically ill patients. JAMA. 2000;284(18):2361–7.

    Article  CAS  PubMed  Google Scholar 

  26. Smailes ST. Non-invasive positive pressure ventilation in burns. Burns. 2002;28(8):795–801.

    Article  CAS  PubMed  Google Scholar 

  27. Warner P. Non-invasive positive pressure ventilation as an adjunct to extubation in the burn patient. J Burn Care Res. 2009;30(1):198–9.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Sipahioğlu, H. (2023). Models of Noninvasive Ventilation Organization in Bioterrorism and Other Catastrophic Conditions. In: Esquinas, A.M., Spicuzza, L., Scala, R. (eds) Noninvasive Ventilation Outside Intensive Care Unit. Noninvasive Ventilation. The Essentials. Springer, Cham. https://doi.org/10.1007/978-3-031-37796-9_31

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-37796-9_31

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-37795-2

  • Online ISBN: 978-3-031-37796-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics