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Glenohumeral Arthritis: Nonoperative Management

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Shoulder Arthritis across the Life Span

Abstract

For nearly all athletes with glenohumeral joint osteoarthritis (OA), symptoms are initially managed non-operatively. Numerous treatment options are available including physical therapy and oral medications, as well as injectable treatments, which include biologic therapies. This chapter will discuss the options available for nonoperative management of the athlete with glenohumeral joint osteoarthritis.

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References

  1. Reineck JR, Krishnan SG, Burkhead WZ. Early glenohumeral arthritis in the competing athlete. Clin Sports Med. 2008;27(4):803–19.

    Article  PubMed  Google Scholar 

  2. Codsi M, Howe CR. Shoulder conditions: diagnosis and treatment guideline. Phys Med Rehabil Clin N Am. 2015;26(3):467–89.

    Article  PubMed  Google Scholar 

  3. Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte A, Coronado-Zarco R, Soria-Bastida MD, Nava-Bringas T, Cruz-Medina E, Olascoaga-Gómez A, Tallabs-Almazan LV, Palencia C. Glenohumeral osteoarthritis: overview, therapy, and rehabilitation. Disabil Rehabil. 2017;39(16):1674–82.

    Article  PubMed  Google Scholar 

  4. Takamura KM, Chen JB, Petrigliano FA. Nonarthroplasty options for the athlete or active individual with shoulder osteoarthritis. Clin Sports Med. 2018;37(4):517–26.

    Article  PubMed  Google Scholar 

  5. Guo JJ, Wu K, Guan H, Zhang L, Ji C, Yang H, Tang T. Three-year follow-up of conservative treatments of shoulder osteoarthritis in older patients. Orthopedics. 2016;39(4):e634–41.

    Article  PubMed  Google Scholar 

  6. Khazzam MS, Pearl ML. AAOS clinical practice guideline: management of glenohumeral joint osteoarthritis. J Am Acad Orthop Surg. 2020;28(19):790–4.

    Article  PubMed  Google Scholar 

  7. Ansok CB, Muh SJ. Optimal management of glenohumeral osteoarthritis. Orthop Res Rev. 2018;10:9–18.

    PubMed  PubMed Central  Google Scholar 

  8. Nissen SE, Yeomans ND, Solomon DH, Lüscher TF, Libby P, Husni ME, Graham DY, Borer JS, Wisniewski LM, Wolski KE, Wang Q. Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis. N Engl J Med. 2016;(375):2519–29.

    Google Scholar 

  9. Zhang W, Jones A, Doherty M. Does paracetamol (acetaminophen) reduce the pain of osteoarthritis?: a meta-analysis of randomised controlled trials. Ann Rheum Dis. 2004;63(8):901–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Green S, Buchbinder R, Hetrick SE. Acupuncture for shoulder pain. Cochrane Database Syst Rev. 2005(2):CD005319.

    Google Scholar 

  11. Stephens MB, Beutler A, O’Connor FG. Musculoskeletal injections: a review of the evidence. Am Fam Physician. 2008;78(8):971–6.

    PubMed  Google Scholar 

  12. Metzger CM, Farooq H, Merrell GA, Kaplan FT, Greenberg JA, Crosby NE, Peck KM, Hoyer RW. Efficacy of a single, image-guided corticosteroid injection for glenohumeral arthritis. J Shoulder Elbow Surg. 2021;30(5):1128–34.

    Article  PubMed  Google Scholar 

  13. Aly AR, Rajasekaran S, Ashworth N. Ultrasound-guided shoulder girdle injections are more accurate and more effective than landmark-guided injections: a systematic review and meta-analysis. Br J Sports Med. 2015;49(16):1042–9.

    Article  PubMed  Google Scholar 

  14. Soh E, Li W, Ong KO, Chen W, Bautista D. Image-guided versus blind corticosteroid injections in adults with shoulder pain: a systematic review. BMC Musculoskelet Disord. 2011;12(1):1–6.

    Article  Google Scholar 

  15. Wernecke C, Braun HJ, Dragoo JL. The effect of intra-articular corticosteroids on articular cartilage: a systematic review. Orthop J Sports Med. 2015;3(5):2325967115581163.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Brockmeier SF, Shaffer BS. Viscosupplementation therapy for osteoarthritis. Sports Med Arthrosc Rev. 2006;14(3):155–62.

    Article  PubMed  Google Scholar 

  17. Ghosh P. The role of hyaluronic acid (hyaluronan) in health and disease: interactions with cells, cartilage and components of synovial fluid. Clin Exp Rheumatol. 1994;12(1):75–82.

    CAS  PubMed  Google Scholar 

  18. Blaine T, Moskowitz R, Udell J, Skyhar M, Levin R, Friedlander J, Daley M, Altman R. Treatment of persistent shoulder pain with sodium hyaluronate: a randomized, controlled trial: a multicenter study. J Bone Joint Surg Am. 2008;90(5):970–9.

    Article  PubMed  Google Scholar 

  19. Zhang B, Thayaparan A, Horner N, Bedi A, Alolabi B, Khan M. Outcomes of hyaluronic acid injections for glenohumeral osteoarthritis: a systematic review and meta-analysis. J Shoulder Elbow Surg. 2019;28(3):596–606.

    Article  PubMed  Google Scholar 

  20. Tran K, Loshak H. Intra-articular hyaluronic acid for viscosupplementation in osteoarthritis of the hand, shoulder, and temporomandibular joint: a review of clinical effectiveness and safety.

    Google Scholar 

  21. Freitag JB, Barnard A. To evaluate the effect of combining photo-activation therapy with platelet-rich plasma injections for the novel treatment of osteoarthritis. BMJ Case Rep. 2013;2013:bcr2012007463.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Kany J, Benkalfate T, Favard L, Teissier P, Charousset C, Flurin PH, Coulet B, Hubert L, Garret J, Valenti P, Werthel JD. Osteoarthritis of the shoulder in under-50 year-olds: a multicenter retrospective study of 273 shoulders by the French Society for Shoulder and Elbow (SOFEC). Orthop Traumatol Surg Res. 2021;107(1):102756.

    Article  PubMed  Google Scholar 

  23. Rossi LA, Piuzzi NS, Shapiro SA. Glenohumeral osteoarthritis: the role for orthobiologic therapies: platelet-rich plasma and cell therapies. JBJS Rev. 2020;8(2):e0075.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Greenberg SM, Kuter DJ, Rosenberg RD. In vitro stimulation of megakaryocyte maturation by megakaryocyte stimulatory factor. J Biol Chem. 1987;262(7):3269–77.

    Article  CAS  PubMed  Google Scholar 

  25. Osterman C, McCarthy MB, Cote MP, Beitzel K, Bradley J, Polkowski G, Mazzocca AD. Platelet-rich plasma increases anti-inflammatory markers in a human coculture model for osteoarthritis. Am J Sports Med. 2015;43(6):1474–84.

    Article  PubMed  Google Scholar 

  26. Bendinelli P, Matteucci E, Dogliotti G, Corsi MM, Banfi G, Maroni P, Desiderio MA. Molecular basis of anti-inflammatory action of platelet-rich plasma on human chondrocytes: mechanisms of NF-κB inhibition via HGF. J Cell Physiol. 2010;225(3):757–66.

    Article  CAS  PubMed  Google Scholar 

  27. Kim HJ, Yeom JS, Koh YG, Yeo JE, Kang KT, Kang YM, Chang BS, Lee CK. Anti-inflammatory effect of platelet-rich plasma on nucleus pulposus cells with response of TNF-α and IL-1. J Orthop Res. 2014;32(4):551–6.

    Article  CAS  PubMed  Google Scholar 

  28. Riboh JC, Saltzman BM, Yanke AB, Fortier L, Cole BJ. Effect of leukocyte concentration on the efficacy of platelet-rich plasma in the treatment of knee osteoarthritis. Am J Sports Med. 2016;44(3):792–800.

    Article  PubMed  Google Scholar 

  29. Orhurhu V, Schwartz R, Potts J, Peck J, Urits I, Orhurhu MS, Odonkor C, Viswanath O, Kaye A, Gill J. Role of Alpha-2-microglobulin in the treatment of osteoarthritic knee pain: a brief review of the literature. Curr Pain Headache Rep. 2019;23(11):1–9.

    Article  Google Scholar 

  30. Zhang Y, Wei X, Browning S, Scuderi G, Hanna LS, Wei L. Targeted designed variants of alpha-2-macroglobulin (A2M) attenuate cartilage degeneration in a rat model of osteoarthritis induced by anterior cruciate ligament transection. Arthritis Res Ther. 2017;19(1):1–1.

    Article  Google Scholar 

  31. LaPrade RF, Geeslin AG, Murray IR, Musahl V, Zlotnicki JP, Petrigliano F, Mann BJ. Biologic treatments for sports injuries II think tank—current concepts, future research, and barriers to advancement, part 1: biologics overview, ligament injury, tendinopathy. Am J Sports Med. 2016;44(12):3270–83.

    Article  PubMed  Google Scholar 

  32. Burrow KL, Hoyland JA, Richardson SM. Human adipose-derived stem cells exhibit enhanced proliferative capacity and retain multipotency longer than donor-matched bone marrow mesenchymal stem cells during expansion in vitro. Stem Cells Int. 2017;2017:2541275.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Centeno CJ, Al-Sayegh H, Bashir J, Goodyear S, Freeman MD. A prospective multi-site registry study of a specific protocol of autologous bone marrow concentrate for the treatment of shoulder rotator cuff tears and osteoarthritis. J Pain Res. 2015;8:269.

    PubMed  PubMed Central  Google Scholar 

  34. Dwyer T, Hoit G, Lee A, Watkins E, Henry P, Leroux T, Veillette C, Theodoropoulos J, Ogilvie-Harris D, Chahal J. Injection of bone marrow aspirate for glenohumeral joint osteoarthritis: a pilot randomized control trial. Arthrosc Sports Med Rehabil. 2021;3(5):e1431–40.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Striano RD, Malanga GA, Bilbool N, Azatullah K. Refractory shoulder pain with osteoarthritis, and rotator cuff tear, treated with micro-fragmented adipose tissue. Orthop Spine Sports Med. 2018;2(1):1–5.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, University of Colorado, Denver, CO, USA

    Joseph Noack & Eric McCarty

  2. Department of Orthopedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, IL, USA

    Mary K. Mulcahey

Authors
  1. Joseph Noack
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  2. Eric McCarty
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  3. Mary K. Mulcahey
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Corresponding author

Correspondence to Mary K. Mulcahey .

Editor information

Editors and Affiliations

  1. Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, USA

    Augustus D. Mazzocca

  2. Department of Orthopedic Surgery and Traumatology, Fundacion Jimenez Diaz Universidad Autonoma, Madrid, Spain

    Emilio Calvo

  3. Concordia Hospital, Rome, Italy

    Giovanni Di Giacomo

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Noack, J., McCarty, E., Mulcahey, M.K. (2023). Glenohumeral Arthritis: Nonoperative Management. In: Mazzocca, A.D., Calvo, E., Di Giacomo, G. (eds) Shoulder Arthritis across the Life Span. Springer, Cham. https://doi.org/10.1007/978-3-031-33298-2_4

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  • DOI: https://doi.org/10.1007/978-3-031-33298-2_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-33297-5

  • Online ISBN: 978-3-031-33298-2

  • eBook Packages: MedicineMedicine (R0)

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