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Disease Models in Viral Research

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Infectious Diseases Drug Delivery Systems

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Abstract

Viral diseases have become a constant threat to human population as the rise of exposure to viruses like Dengue, Measles, Chikungunya, Influenza, SARS-CoV-2, Zika, and Ebola increased. To tackle this emerging problem, it is important to investigate the pathogenesis and immune responses by implementing various animal models. Animal models are also utilized in identifying newer drug targets, evaluating efficacy and potential toxicity of new drug and vaccine candidates. Furthermore, no single animal model can mimic all clinical manifestations of the human disease; understanding the lacunas of available models helps in choosing the model for a particular experiment. In this chapter, we cover the animal models, which include nonhuman primates, rodents used for various viral diseases and shows the areas where there is gap in knowledge.

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Authors and Affiliations

  1. Ocular Pharmacology and Pharmacy Division, Dr.R.P.Centre, AIIMS, New Delhi, India

    Tapas Kumar Roy

  2. Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Haringhata, Nadia, India

    Sandipan Dasgupta

  3. Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana, India

    Arnab Roy

  4. Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India

    Bhaskar Mazumder

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  1. Tapas Kumar Roy
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  4. Bhaskar Mazumder
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  1. CapnoPharm GmbH, Tübingen, Germany

    Ranjita Shegokar

  2. Taneja College of Pharmacy, University of South Florida, Tampa, FL, USA

    Yashwant Pathak

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Roy, T.K., Dasgupta, S., Roy, A., Mazumder, B. (2023). Disease Models in Viral Research. In: Shegokar, R., Pathak, Y. (eds) Infectious Diseases Drug Delivery Systems. Springer, Cham. https://doi.org/10.1007/978-3-031-20521-7_10

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