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18F-FP-DTBZ

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PET Radiopharmaceuticals

Part of the book series: Clinicians’ Guides to Radionuclide Hybrid Imaging ((PET/CT))

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Abstract

FP-DTBZ is a marker of the vesicular monoamine transporter type-2 (VMAT2) and is used in evaluation of Parkinson’s disease.

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Further Reading

  • Lin KJ, Lin WY, Hsieh CJ, et al. Optimal scanning time window for 18F-FP-(+)-DTBZ (18F-AV-133) summed uptake measurements. Nucl Med Biol. 2011;38:1149–55.

    Article  CAS  PubMed  Google Scholar 

  • Lin KJ, Weng YH, Hsieh CJ, et al. Brain imaging of vesicular monoamine transporter type 2 in healthy aging subjects by 18F-FP-(+)-DTBZ PET. PLoS One. 2013;8:e75952.

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  • Lin KJ, Weng YH, Wey SP, et al. Whole-body biodistribution and radiation dosimetry of 18F-FP-(+)-DTBZ (18F-AV-133): a novel vesicular monoamine transporter 2 imaging agent. J Nucl Med. 2010;51:1480–5.

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  • Zhao C, Liu C, Tang J, et al. An efficient automated radiosynthesis and bioactivity confirmation of VMAT2 tracer [18F]FP-(+)-DTBZ. Mol Imaging Biol. 2020;22:265–73.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK

    James R. Ballinger

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  1. James R. Ballinger
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Correspondence to James R. Ballinger .

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© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Ballinger, J.R. (2022). 18F-FP-DTBZ. In: PET Radiopharmaceuticals. Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-031-10271-4_51

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  • DOI: https://doi.org/10.1007/978-3-031-10271-4_51

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-10270-7

  • Online ISBN: 978-3-031-10271-4

  • eBook Packages: MedicineMedicine (R0)

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