Abstract
Assessing the risk of having clinically significant portal hypertension (CSPH) by noninvasive tools in patients with compensated advanced chronic liver disease (cACLD) will be important to implement therapeutic strategies to prevent liver decompensation in those patients. Since Baveno VI, the new relevant information has allowed to refine these noninvasive criteria using liver stiffness measurement and platelet counts. Risk prediction models for CSPH have been reported and validated for viral and alcohol etiologies and can be used to make clinical decisions. In addition, a 25 kPa threshold of liver stiffness can be used to select cACLD patients with a high probability of presenting CSPH. A new risk prediction model for patients with nonalcoholic steatohepatitis has also been developed. Finally, rules for excluding CSPH with high sensitivity and negative predictive value are now available.
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Pons, M., Aceituno, L., Genescà, J. (2022). Noninvasive Detection of Clinically Significant Portal Hypertension with Liver Elastography. In: de Franchis, R. (eds) Portal Hypertension VII. Springer, Cham. https://doi.org/10.1007/978-3-031-08552-9_9
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