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Pathologic Myopia

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Abstract

Pathologic myopia is among the most frequent causes of blindness and vision loss in the world, with a prevalence of 0.9–3.1%. Both environmental and genetic factors have been shown to play a role in pathogenesis of this disease. Increased axial length in these patients causes a broad spectrum of structural changes in different parts of the globe like optic disc, retina, vitreous and choroid that can affect vision. Recent developments in optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) allowed better visualization of these changes with more details. OCT seems to be the preferred method for diagnosis and even follow up of most complications of pathologic myopia. In this chapter, we tried to show the most common and important complications of pathologic myopia OCT and OCTA features.

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References

  1. Wong TY, Ferreira A, Hughes R, Carter G, Mitchell P. Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review. Am J Ophthalmol. 2014;157:9-25.e12.

    Article  Google Scholar 

  2. Henaine-Berra A, Zand-Hadas IM, Fromow-Guerra J, García-Aguirre GP. Prevalence of macular anatomic abnormalities in high myopia. Ophthalmic Surg Lasers Imaging Retina. 2013;44:140–4.

    Article  Google Scholar 

  3. You QS, Peng XY, Xu L, Chen CX, Wang YX, Jonas JB. Myopic maculopathy imaged by optical coherence tomography: the Beijing Eye Study. Ophthalmology. 2014;121:220–4.

    Article  Google Scholar 

  4. Forte R, Cennamo G, Pascotto F, de Crecchio G. En face optical coherence tomography of the posterior pole in high myopia. Am J Ophthalmol. 2008;145:281–8.

    Article  Google Scholar 

  5. Shimada N, Ohno-Matsui K, Nishimuta A, Moriyama M, Yoshida T, Tokoro T, et al. Detection of paravascular lamellar holes and other paravascular abnormalities by optical coherence tomography in eyes with high myopia. Ophthalmology. 2008;115:708–17.

    Article  Google Scholar 

  6. Takano M, Kishi S. Foveal retinoschisis and retinal detachment in severely myopic eyes with posterior staphyloma. Am J Ophthalmol. 1999;128:472–6.

    Article  CAS  Google Scholar 

  7. Cheng C, Teo K, Tan CS, Lee SY, Loh BK, Wong E, et al. Myopic retinoschisis in Asians: structural features and determinants of visual acuity and prognostic factors for progression. Retina. 2016;36:717–26.

    Article  Google Scholar 

  8. Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, et al. International photographic classification and grading system for myopic maculopathy. Am J Ophthalmol. 2015;159(5):877–83.

    Google Scholar 

  9. Shimada N, Ohno-Matsui K, Nishimuta A, Tokoro T, Mochizuki M. Peripapillary changes detected by optical coherence tomography in eyes with high myopia. Ophthalmology. 2007;114:2070–6.

    Article  Google Scholar 

  10. Shinohara K, Moriyama M, Shimada N, Yoshida T, Ohno-Matsui K. Characteristics of peripapillary staphylomas associated with high myopia determined by swept-source optical coherence tomography. Am J Ophthalmol. 2016;169:138–44.

    Article  Google Scholar 

  11. Muraoka Y, Tsujikawa A, Hata M, Yamashiro K, Ellabban AA, Takahashi A, et al. Paravascular inner retinal defect associated with high myopia or epiretinal membrane. JAMA Ophthalmol. 2015;133:413–20.

    Article  Google Scholar 

  12. Chan NS, Teo K, Cheung CM. Epidemiology and diagnosis of myopic choroidal neovascularization in Asia. Eye Contact Lens. 2016;42:48–55.

    Article  Google Scholar 

  13. Leveziel N, Yu Y, Reynolds R, Tai A, Meng W, Caillaux V, et al. Genetic factors for choroidal neovascularization associated with high myopia. Invest Ophthalmol Vis Sci. 2012;53:5004–9.

    Article  Google Scholar 

  14. Ikuno Y, Jo Y, Hamasaki T, et al. Ocular risk factors for choroidal neovascularization in pathologic myopia. Invest Ophthalmol Vis Sci. 2010;51:3721–5.

    Article  Google Scholar 

  15. Verteporfin in Photodynamic Therapy Study Group. Photodynamic therapy of subfoveal choroidal neovascularization in pathologic myopia with verteporfin. 1-year results of a randomized clinical trial—VIP Report no.1. Ophthalmology. 2001;108:841–5.

    Google Scholar 

  16. Neelam K, Cheung CM, Ohno-Matsui K, Lai TY, Wong TY. Choroidal neovascularization in pathological myopia. Prog Retin Eye Res. 2012;31:495–525.

    Article  CAS  Google Scholar 

  17. Wong TY, Ohno-Matsui K, Leveziel N, Holz FG, Lai TY, Yu HG, et al. Myopic choroidal neovascularisation: current concepts and update on clinical management. Br J Ophthalmol. 2015;99:289–96.

    Article  Google Scholar 

  18. Ikuno Y, Fujimoto S, Jo Y, Asai T, Nishida K. Choroidal thinning in high myopia measured by optical coherence tomography. Clin Ophthalmol. 2013;7:889.

    Article  Google Scholar 

  19. Ikuno Y, Tano Y. Retinal and choroidal biometry in highly myopic eyes with spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2009;50:3876–80.

    Article  Google Scholar 

  20. Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. Am J Ophthalmol. 2009;148:445–50.

    Article  Google Scholar 

  21. Flores-Moreno I, Lugo F, Duker JS, Ruiz-Moreno JM. The relationship between axial length and choroidal thickness in eyes with high myopia. Am J Ophthalmol. 2013;155:314–9.

    Article  Google Scholar 

  22. Usui S, Ikuno Y, Miki A, Matsushita K, Yasuno Y, Nishida K. Evaluation of the choroidal thickness using high-penetration optical coherence tomography with long wavelength in highly myopic normal-tension glaucoma. Am J Ophthalmol. 2012;153:10–6.

    Article  Google Scholar 

  23. Ohsugi H, Ikuno Y, Oshima K, Yamauchi T, Tabuchi H. Morphologic characteristics of macular complications of a dome-shaped macula determined by swept-source optical coherence tomography. Am J Ophthalmol. 2014;158:162-70.e1.

    Article  Google Scholar 

  24. You QS, Peng XY, Xu L, Chen CX, Wei WB, Wang Y, et al. Macular Bruchs membrane defects in highly myopic eyes: the Beijing Eye study. Retina. 2016;36:517–23.

    Article  Google Scholar 

  25. Ohno-Matsui K, Jonas JB, Spaide RF. Macular Bruch membrane holes in highly myopic patchy chorioretinal atrophy. Am J Ophthalmol. 2016;166:22–8.

    Article  Google Scholar 

  26. Leung CK, Mohamed S, Leung KS. Retinal nerve fiber layer measurements in myopia: an optical coherence tomography study. Invest Ophthalmol Vis Sci. 2006;47:5171–6.

    Article  Google Scholar 

  27. Choi YJ, Jeoung JW, Park KH, Kim DM. Glaucoma detection ability of ganglion cell-inner plexiform layer thickness by spectral-domain optical coherence tomography in high myopia. Invest Ophthalmol Vis Sci 2013;54 2296–304.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Narges Hassanpoor

  2. Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran

    Fedra Hajizadeh

Authors
  1. Narges Hassanpoor
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  2. Fedra Hajizadeh
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Correspondence to Fedra Hajizadeh .

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Editors and Affiliations

  1. Noor Eye Hospital, Tehran, Iran

    Fedra Hajizadeh

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Hassanpoor, N., Hajizadeh, F. (2022). Pathologic Myopia. In: Hajizadeh, F. (eds) Atlas of Ocular Optical Coherence Tomography. Springer, Cham. https://doi.org/10.1007/978-3-031-07410-3_8

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  • DOI: https://doi.org/10.1007/978-3-031-07410-3_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-07409-7

  • Online ISBN: 978-3-031-07410-3

  • eBook Packages: MedicineMedicine (R0)

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