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Diagnosis of Obstructive Sleep Apnea in Patients with Associated Comorbidity

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Advances in the Diagnosis and Treatment of Sleep Apnea

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1384))

Abstract

Obstructive sleep apnea (OSA) is a heterogeneous disease with many physiological implications. OSA is associated with a great diversity of diseases, with which it shares common and very often bidirectional pathophysiological mechanisms, leading to significantly negative implications on morbidity and mortality. In these patients, underdiagnosis of OSA is high. Concerning cardiorespiratory comorbidities, several studies have assessed the usefulness of simplified screening tests for OSA in patients with hypertension, COPD, heart failure, atrial fibrillation, stroke, morbid obesity, and in hospitalized elders.

The key question is whether there is any benefit in the screening for the existence of OSA in patients with comorbidities. In this regard, there are few studies evaluating the performance of the various diagnostic procedures in patients at high risk for OSA. The purpose of this chapter is to review the existing literature about diagnosis in those diseases with a high risk for OSA, with special reference to artificial intelligence-related methods.

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Acknowledgments

This work was supported in part by “Ministerio de Ciencia e Innovación-Agencia Estatal de Investigación” and “European Regional Development Fund (FEDER)” under Projects PID2020-115468RB-I00 and RTC-2017-6516-1, in part by “Sociedad Española de Neumología y Cirugía Torácica (SEPAR)” under project 649/2018, by “Sociedad Española de Sueño (SES)” under project “Beca de Investigación SES 2019”, and in part by “Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, (CIBER-BBN), Spain” through “Instituto de Salud Carlos III” co-funded with FEDER funds. The work of Daniel Álvarez was supported by a “Ramón y Cajal” grant (RYC2019-028566-I) from the “Ministerio de Ciencia e Innovación – Agencia Estatal de Inves-tigación” co-funded by the European Social Fund.

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del Campo, F., Arroyo, C.A., Zamarrón, C., Álvarez, D. (2022). Diagnosis of Obstructive Sleep Apnea in Patients with Associated Comorbidity. In: Penzel, T., Hornero, R. (eds) Advances in the Diagnosis and Treatment of Sleep Apnea . Advances in Experimental Medicine and Biology, vol 1384. Springer, Cham. https://doi.org/10.1007/978-3-031-06413-5_4

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