Electrochemical Methods Applied for Bioanalysis: Differential Pulse Voltammetry and Square Wave Voltammetry

Abstract

The theory and applications of differential pulse voltammetry and square wave voltammetry for bioanalysis are discussed here. Electrochemical pulse techniques have been frequently employed for the quantification of several biomolecules due to their characteristic properties which allow, for example, miniaturization and utilization in situ and, even, in vivo. Pulse techniques have the advantage of minimizing the contribution of capacitive currents to the total measured signal. This advantage is important since capacitive currents are not dependent on the analyte concentration in the solution. Here, the application of such techniques in electrochemical sensors and biosensors is reviewed, for different biological analytes.