Skip to main content
SpringerLink
Log in

Is Vaccine Prophylaxis Necessary for Patients Undergoing Splenic Embolization?

  • Chapter
  • First Online:
Difficult Decisions in Trauma Surgery

Part of the book series: Difficult Decisions in Surgery: An Evidence-Based Approach ((DDSURGERY))

  • 1011 Accesses

Abstract

Controversy exists regarding the need for immunizations after splenic artery embolization following traumatic splenic injuries. To date, evidence suggests that routine vaccination after splenic embolization may not be necessary; however, the quality of such evidence requires examination before definitive recommendations can be provided.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. King H, Schumacher HB Jr. Splenic studies. I. Susceptibility to infection after splenectomy performed in infancy. Ann Surg. 1952;136(2):239–42.

    Article  CAS  Google Scholar 

  2. Davidson RN, Wall RA. Prevention and management of infections in patients without a spleen. Clin Microbiol Infect. 2001;7(12):657–60.

    Article  CAS  Google Scholar 

  3. Sinwar PD. Overwhelming post-splenectomy syndrome – review study. Int J Surg. 2014;12(12):1314–6.

    Article  Google Scholar 

  4. Ezeanolue E, Harriman K, Hunter P, Kroger A, Pellegrini C. General best practice guidelines for immunization. Best practices guidance of the advisory committee on immunization practices (ACIP). [www.cdc.gov/vaccines/hcp/acip-recs/general-recs/downloads/general-recs.pdf]. Accessed 7 Dec 2019.

  5. Brigden ML. Overwhelming postsplenectomy infection still a problem. West J Med. 1992;157(4):440–3.

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Stassen NA, Bhullar I, Cheng JD, Crandall ML. Selective nonoperative management of blunt splenic injury: an eastern Association for the Surgery of trauma practice management guideline. J Trauma Acute Care Surg. 2012;73(5 Suppl 4):S294–300.

    Article  Google Scholar 

  7. Crooker KG, Howard JM, Alvarado AR. Splenic embolization after trauma: an opportunity to improve best immunization practices. J Surg Res. 2018;232:293–7.

    Article  Google Scholar 

  8. Bessoud B, Duchosal MA, Siegrist CA, et al. Proximal splenic artery embolization for blunt splenic injury: clinical, immunologic, and ultrasound-Doppler follow-up. J Trauma. 2007;62(6):1481–6.

    PubMed  Google Scholar 

  9. Nakae H, Shimazu T, Miyauchi H, et al. Does splenic preservation treatment (embolization, splenorrhaphy, and partial splenectomy) improve immunologic function and long-term prognosis after splenic injury? J Trauma. 2009;67(3):557–63. discussion 563-4

    PubMed  Google Scholar 

  10. Malhotra AK, Carter RF, Lebman DA, et al. Preservation of splenic immunocompetence after splenic artery angioembolization for blunt splenic injury. J Trauma. 2010;69(5):1126–30. discussion 1130-1

    PubMed  Google Scholar 

  11. Skattum J, Titze TL, Dormagen JB, et al. Preserved splenic function after angioembolisation of high grade injury. Injury. 2012;43(1):62–6.

    Article  Google Scholar 

  12. Skattum J, Loekke RJ, Titze TL, et al. Preserved function after angioembolisation of splenic injury in children and adolescents: a case control study. Injury. 2014;45(1):156–9.

    Article  Google Scholar 

  13. Olthof DC, Lammers AJ, van Leeuwen EM, et al. Antibody response to a T-cell-independent antigen is preserved after splenic artery embolization for trauma. Clin Vaccine Immunol. 2014;21(11):1500–4.

    Article  CAS  Google Scholar 

  14. Foley PT, Kavnoudias H, Cameron PU, et al. Proximal versus distal splenic artery embolisation for blunt splenic trauma: what is the impact on splenic immune function? Cardiovasc Intervent Radiol. 2015;38(5):1143–51.

    Article  CAS  Google Scholar 

  15. Falimirski M, Syed A, Prybilla D. Immunocompetence of the severely injured spleen verified by differential interference contrast microscopy: the red blood cell pit test. J Trauma. 2007;63:1087–92.

    PubMed  Google Scholar 

  16. Tominaga GT, Simon FJ Jr, Dandan IS, Schaffer KB, Kraus JF, Kan M, et al. Immunologic function after splenic embolization, is there a difference? J Trauma. 2009;67(2):289–95.

    PubMed  Google Scholar 

  17. Shih HC, Wang CY, Wen YS, Wu JK, Huang MS, Huang CI, et al. Spleen artery embolization aggravates endotoxin hyporesponse of peripheral blood mononuclear cells in patients with spleen injury. J Trauma. 2010;68(3):532–7.

    PubMed  Google Scholar 

  18. Pirasteh A, Snyder LL, Lin R, Rosenblum D, Reed S, Sattar A, et al. Temporal assessment of splenic function in patients who have undergone percutaneous image-guided splenic artery embolization in the setting of trauma. J Vasc Interv Radiol. 2012;23(1):80–2.

    Article  Google Scholar 

  19. Walusimbi MS, Dominguez KM, Sands JM, Markert RJ, McCarthy MC. Circulating cellular and humoral elements of immune function following splenic arterial embolisation or splenectomy in trauma patients. Injury. 2012;43(2):180–3.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The University of Chicago Medicine, Chicago, IL, USA

    Mary Kate Johnson & Natasha N. Pettit

Authors
  1. Mary Kate Johnson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Natasha N. Pettit
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mary Kate Johnson .

Editor information

Editors and Affiliations

  1. Department of Surgery, University of Chicago, Chicago, IL, USA

    Kenneth Wilson

  2. Department of Surgery, University of Chicago, Chicago, IL, USA

    Selwyn O. Rogers

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Johnson, M.K., Pettit, N.N. (2022). Is Vaccine Prophylaxis Necessary for Patients Undergoing Splenic Embolization?. In: Wilson, K., Rogers, S.O. (eds) Difficult Decisions in Trauma Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-81667-4_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-81667-4_11

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-81666-7

  • Online ISBN: 978-3-030-81667-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation