Skip to main content

Ultrasound in Osteoarthritis

  • Chapter
  • First Online:
Musculoskeletal Ultrasound in Rheumatology Review

Abstract

Osteoarthritis (OA) is the most common type of arthritis and is increasing in prevalence with a large burden on the individual, society, and the health-care system. OA has traditionally been imaged with conventional radiography although this modality has several drawbacks including insensitivity to early/mild disease and change over time. Ultrasound provides a number of benefits over radiography while remaining accessible and relatively cost-effective, making it an attractive option for early and repeated imaging in this common disease.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Hootman JM, Helmick CG, Barbour KE, Theis KA, Boring MA. Updated projected prevalence of self-reported doctor-diagnosed arthritis and arthritis-attributable activity limitation among US adults, 2015–2040. Arthritis Rheumatol. 2016;68(7):1582–7. https://doi.org/10.1002/art.39692.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Jafarzadeh SR, Felson DT. Corrected estimates for the prevalence of self-reported doctor-diagnosed arthritis among US adults: comment on the article by Hootman et al. Arthritis Rheumatol. 2017;69(8):1701–2. https://doi.org/10.1002/art.40144.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Osteoarthritis Research Society International. Osteoarthritis: a serious disease. 2016:1–103. Available from: https://www.oarsi.org/sites/default/files/docs/2016/oarsi_white_paper_oa_serious_disease_121416_1.pdf

  4. Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum. 1991;34(5):505–14.

    Article  CAS  PubMed  Google Scholar 

  5. Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis Rheum. 1990;33(11):1601–10.

    Article  CAS  PubMed  Google Scholar 

  6. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 1986;29(8):1039–49.

    Article  CAS  PubMed  Google Scholar 

  7. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16(4):494–502. https://doi.org/10.1136/ard.16.4.494.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. van Oudenaarde K, Jobke B, Oostveen AC, Marijnissen AC, Wolterbeek R, Wesseling J, et al. Predictive value of MRI features for development of radiographic osteoarthritis in a cohort of participants with pre-radiographic knee osteoarthritis-the CHECK study. Rheumatology (Oxford). 2017;56(1):113–20. https://doi.org/10.1093/rheumatology/kew368.

    Article  Google Scholar 

  9. Emery CA, Whittaker JL, Mahmoudian A, Lohmander LS, Roos EM, Bennell KL, et al. Establishing outcome measures in early knee osteoarthritis. Nat Rev Rheumatol. 2019;15(7):438–48. https://doi.org/10.1038/s41584-019-0237-3.

    Article  PubMed  Google Scholar 

  10. Hunter DJ, Arden N, Conaghan PG, Eckstein F, Gold G, Grainger A, et al. Definition of osteoarthritis on MRI: results of a Delphi exercise. Osteoarthr Cartil. 2011;19(8):963–9. https://doi.org/10.1016/j.joca.2011.04.017.

    Article  CAS  Google Scholar 

  11. Bruyn GA, Iagnocco A, Naredo E, Balint PV, Gutierrez M, Hammer HB, et al. OMERACT definitions for ultrasonographic pathologies and elementary lesions of rheumatic disorders 15 years on. J Rheumatol. 2019;46(10):1388–93. https://doi.org/10.3899/jrheum.181095.

    Article  PubMed  Google Scholar 

  12. Bastick AN, Runhaar J, Belo JN, Bierma-Zeinstra SM. Prognostic factors for progression of clinical osteoarthritis of the knee: a systematic review of observational studies. Arthritis Res Ther. 2015;17:152. https://doi.org/10.1186/s13075-015-0670-x.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Hill CL, Hunter DJ, Niu J, Clancy M, Guermazi A, Genant H, et al. Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis. Ann Rheum Dis. 2007;66(12):1599–603. https://doi.org/10.1136/ard.2006.067470.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Torres L, Dunlop DD, Peterfy C, Guermazi A, Prasad P, Hayes KW, et al. The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis. Osteoarthr Cartil. 2006;14(10):1033–40. https://doi.org/10.1016/j.joca.2006.03.015.

    Article  CAS  Google Scholar 

  15. Neogi T, Guermazi A, Roemer F, Nevitt MC, Scholz J, Arendt-Nielsen L, et al. Association of joint inflammation with pain sensitization in knee osteoarthritis: the multicenter osteoarthritis study. Arthritis Rheumatol. 2016;68(3):654–61. https://doi.org/10.1002/art.39488.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Gibson N, Guermazi A, Clancy M, Niu J, Grayson P, Aliabadi P, et al. Relation of hand enthesophytes with knee enthesopathy: is osteoarthritis related to a systemic enthesopathy? J Rheumatol. 2012;39(2):359–64. https://doi.org/10.3899/jrheum.110718.

    Article  PubMed  Google Scholar 

  17. Rogers J, Shepstone L, Dieppe P. Is osteoarthritis a systemic disorder of bone? Arthritis Rheum. 2004;50(2):452–7. https://doi.org/10.1002/art.20136.

    Article  PubMed  Google Scholar 

  18. Finzel S, Sahinbegovic E, Kocijan R, Engelke K, Englbrecht M, Schett G. Inflammatory bone spur formation in psoriatic arthritis is different from bone spur formation in hand osteoarthritis. Arthritis Rheumatol. 2014;66(11):2968–75. https://doi.org/10.1002/art.38794.

    Article  PubMed  Google Scholar 

  19. Okano T, Mamoto K, Di Carlo M, Salaffi F. Clinical utility and potential of ultrasound in osteoarthritis. Radiol Med. 2019;124(11):1101–11. https://doi.org/10.1007/s11547-019-01013-z.

    Article  PubMed  Google Scholar 

  20. Schmidt WA, Schmidt H, Schicke B, Gromnica-Ihle E. Standard reference values for musculoskeletal ultrasonography. Ann Rheum Dis. 2004;63(8):988–94. https://doi.org/10.1136/ard.2003.015081.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Naredo E, Acebes C, Moller I, Canillas F, de Agustin JJ, de Miguel E, et al. Ultrasound validity in the measurement of knee cartilage thickness. Ann Rheum Dis. 2009;68(8):1322–7. https://doi.org/10.1136/ard.2008.090738.

    Article  CAS  PubMed  Google Scholar 

  22. Saarakkala S, Waris P, Waris V, Tarkiainen I, Karvanen E, Aarnio J, et al. Diagnostic performance of knee ultrasonography for detecting degenerative changes of articular cartilage. Osteoarthr Cartil. 2012;20(5):376–81. https://doi.org/10.1016/j.joca.2012.01.016.

    Article  CAS  Google Scholar 

  23. Gossec L, Jordan JM, Mazzuca SA, Lam MA, Suarez-Almazor ME, Renner JB, et al. Comparative evaluation of three semi-quantitative radiographic grading techniques for knee osteoarthritis in terms of validity and reproducibility in 1759 X-rays: report of the OARSI-OMERACT task force. Osteoarthr Cartil. 2008;16(7):742–8. https://doi.org/10.1016/j.joca.2008.02.021.

    Article  CAS  Google Scholar 

  24. Hunter DJ, Zhang W, Conaghan PG, Hirko K, Menashe L, Reichmann WM, et al. Responsiveness and reliability of MRI in knee osteoarthritis: a meta-analysis of published evidence. Osteoarthr Cartil. 2011;19(5):589–605. https://doi.org/10.1016/j.joca.2010.10.030.

    Article  CAS  Google Scholar 

  25. Oo WM, Linklater JM, Daniel M, Saarakkala S, Samuels J, Conaghan PG, et al. Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis. Osteoarthr Cartil. 2018;26(5):601–11. https://doi.org/10.1016/j.joca.2018.01.021.

    Article  CAS  Google Scholar 

  26. Bruyn GA, Naredo E, Damjanov N, Bachta A, Baudoin P, Hammer HB, et al. An OMERACT reliability exercise of inflammatory and structural abnormalities in patients with knee osteoarthritis using ultrasound assessment. Ann Rheum Dis. 2016;75(5):842–6. https://doi.org/10.1136/annrheumdis-2014-206774.

    Article  PubMed  Google Scholar 

  27. Hammer HB, Iagnocco A, Mathiessen A, Filippucci E, Gandjbakhch F, Kortekaas MC, et al. Global ultrasound assessment of structural lesions in osteoarthritis: a reliability study by the OMERACT ultrasonography group on scoring cartilage and osteophytes in finger joints. Ann Rheum Dis. 2016;75(2):402–7. https://doi.org/10.1136/annrheumdis-2014-206289.

    Article  CAS  PubMed  Google Scholar 

  28. Zabotti A, Filippou G, Canzoni M, Adinolfi A, Picerno V, Carrara G, et al. OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot. RMD Open. 2019;5(1):e000795. https://doi.org/10.1136/rmdopen-2018-000795.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Iagnocco A, Naredo E. Ultrasound of the osteoarthritic joint. Clin Exp Rheumatol. 2017;35(3):527–34.

    PubMed  Google Scholar 

  30. Gullo TR, Golightly YM, Cleveland RJ, Renner JB, Callahan LF, Jordan JM, et al. Defining multiple joint osteoarthritis, its frequency and impact in a community-based cohort. Semin Arthritis Rheum. 2019;48(6):950–7. https://doi.org/10.1016/j.semarthrit.2018.10.001.

    Article  PubMed  Google Scholar 

  31. Qin J, Barbour KE, Murphy LB, Nelson AE, Schwartz TA, Helmick CG, et al. Lifetime risk of symptomatic hand osteoarthritis: the Johnston County Osteoarthritis Project. Arthritis Rheumatol. 2017;69(6):1204–12. https://doi.org/10.1002/art.40097.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Abraham AM, Pearce MS, Mann KD, Francis RM, Birrell F. Population prevalence of ultrasound features of osteoarthritis in the hand, knee and hip at age 63 years: the Newcastle thousand families birth cohort. BMC Musculoskelet Disord. 2014;15:162. https://doi.org/10.1186/1471-2474-15-162.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Oo WM, Deveza LA, Duong V, Fu K, Linklater JM, Riordan EA, et al. Musculoskeletal ultrasound in symptomatic thumb-base osteoarthritis: clinical, functional, radiological and muscle strength associations. BMC Musculoskelet Disord. 2019;20(1):220. https://doi.org/10.1186/s12891-019-2610-4.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Checa A, Panahi E. Clinical images: is ultrasonography better than radiography for determining the need for surgical treatment in patients with carpometacarpal osteoarthritis? Arthritis Rheumatol. 2014;66(7):1954. https://doi.org/10.1002/art.38619.

    Article  PubMed  Google Scholar 

  35. Spahn G, Lipfert JU, Maurer C, Hartmann B, Schiele R, Klemm HT, et al. Risk factors for cartilage damage and osteoarthritis of the elbow joint: case-control study and systematic literature review. Arch Orthop Trauma Surg. 2017;137(4):557–66. https://doi.org/10.1007/s00402-017-2654-6.

    Article  PubMed  Google Scholar 

  36. Bodor M, Fullerton B. Ultrasonography of the hand, wrist, and elbow. Phys Med Rehabil Clin N Am. 2010;21(3):509–31. https://doi.org/10.1016/j.pmr.2010.04.003.

    Article  PubMed  Google Scholar 

  37. Menge TJ, Boykin RE, Bushnell BD, Byram IR. Acromioclavicular osteoarthritis: a common cause of shoulder pain. South Med J. 2014;107(5):324–9. https://doi.org/10.1097/SMJ.0000000000000101.

    Article  PubMed  Google Scholar 

  38. Blankstein A, Ganel A, Givon U, Dudkiewicz I, Perry M, Diamant L, et al. Ultrasonography as a diagnostic modality in acromioclavicular joint pathologies. Isr Med Assoc J. 2005;7(1):28–30.

    PubMed  Google Scholar 

  39. Iagnocco A, Filippucci E, Riente L, Meenagh G, Delle Sedie A, Sakellariu G, et al. Ultrasound imaging for the rheumatologist XLI. Sonographic assessment of the hip in OA patients. Clin Exp Rheumatol. 2012;30(5):652–7.

    PubMed  Google Scholar 

  40. Malas FU, Kara M, Kaymak B, Akinci A, Ozcakar L. Ultrasonographic evaluation in symptomatic knee osteoarthritis: clinical and radiological correlation. Int J Rheum Dis. 2014;17(5):536–40. https://doi.org/10.1111/1756-185X.12190.

    Article  PubMed  Google Scholar 

  41. Abbasi B, Pezeshki-Rad M, Akhavan R, Sahebari M. Association between clinical and sonographic synovitis in patients with painful knee osteoarthritis. Int J Rheum Dis. 2017;20(5):561–6. https://doi.org/10.1111/1756-185X.12834.

    Article  PubMed  Google Scholar 

  42. Sarmanova A, Hall M, Moses J, Doherty M, Zhang W. Synovial changes detected by ultrasound in people with knee osteoarthritis – a meta-analysis of observational studies. Osteoarthr Cartil. 2016;24(8):1376–83. https://doi.org/10.1016/j.joca.2016.03.004.

    Article  CAS  Google Scholar 

  43. Chiba D, Tsuda E, Maeda S, Sasaki E, Takahashi I, Nakaji S, et al. Evaluation of a quantitative measurement of suprapatellar effusion by ultrasonography and its association with symptoms of radiographic knee osteoarthritis: a cross-sectional observational study. Arthritis Res Ther. 2016;18:181. https://doi.org/10.1186/s13075-016-1078-y.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Bevers K, Vriezekolk JE, Bijlsma JW, van den Ende CH, den Broeder AA. Ultrasonographic predictors for clinical and radiological progression in knee osteoarthritis after 2 years of follow-up. Rheumatology (Oxford). 2015;54(11):2000–3. https://doi.org/10.1093/rheumatology/kev224.

    Article  Google Scholar 

  45. Sarmanova A, Hall M, Fernandes GS, Valdes AM, Walsh DA, Doherty M, et al. Thresholds of ultrasound synovial abnormalities for knee osteoarthritis - a cross sectional study in the general population. Osteoarthr Cartil. 2019;27(3):435–43. https://doi.org/10.1016/j.joca.2018.09.018.

    Article  CAS  Google Scholar 

  46. Keen HI, Hensor EM, Wakefield RJ, Mease PJ, Bingham CO 3rd, Conaghan PG. Ultrasound assessment of response to intra-articular therapy in osteoarthritis of the knee. Rheumatology (Oxford). 2015;54(8):1385–91. https://doi.org/10.1093/rheumatology/keu529.

    Article  CAS  Google Scholar 

  47. Conaghan PG, D’Agostino MA, Le Bars M, Baron G, Schmidely N, Wakefield R, et al. Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study. Ann Rheum Dis. 2010;69(4):644–7. https://doi.org/10.1136/ard.2008.099564.

    Article  CAS  PubMed  Google Scholar 

  48. Wu PT, Shao CJ, Wu KC, Wu TT, Chern TC, Kuo LC, et al. Pain in patients with equal radiographic grades of osteoarthritis in both knees: the value of gray scale ultrasound. Osteoarthr Cartil. 2012;20(12):1507–13. https://doi.org/10.1016/j.joca.2012.08.021.

    Article  Google Scholar 

  49. Gutierrez M, Di Geso L, Salaffi F, Carotti M, Girolimetti R, De Angelis R, et al. Ultrasound detection of cartilage calcification at knee level in calcium pyrophosphate deposition disease. Arthritis Care Res (Hoboken). 2014;66(1):69–73. https://doi.org/10.1002/acr.22190.

    Article  CAS  Google Scholar 

  50. Filippou G, Adinolfi A, Iagnocco A, Filippucci E, Cimmino MA, Bertoldi I, et al. Ultrasound in the diagnosis of calcium pyrophosphate dihydrate deposition disease. A systematic literature review and a meta-analysis. Osteoarthr Cartil. 2016;24(6):973–81. https://doi.org/10.1016/j.joca.2016.01.136.

    Article  CAS  Google Scholar 

  51. Lee KA, Lee SH, Kim HR. Diagnostic value of ultrasound in calcium pyrophosphate deposition disease of the knee joint. Osteoarthr Cartil. 2019;27(5):781–7. https://doi.org/10.1016/j.joca.2018.11.013.

    Article  Google Scholar 

  52. Zhang W, Doherty M, Bardin T, Barskova V, Guerne PA, Jansen TL, et al. European league against rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis. 2011;70(4):563–70. https://doi.org/10.1136/ard.2010.139105.

    Article  CAS  PubMed  Google Scholar 

  53. Han BK, Kim W, Niu J, Basnyat S, Barshay V, Gaughan JP, et al. Association of chondrocalcinosis in knee joints with pain and synovitis: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2017;69(11):1651–8. https://doi.org/10.1002/acr.23208.

    Article  Google Scholar 

  54. Karimzadeh H, Sirous M, Sadati SN, Bashshash M, Mottaghi P, Ommani B, et al. Prevalence of chondrocalcinosis in patients above 50 years and the relationship with osteoarthritis. Adv Biomed Res. 2017;6:98. https://doi.org/10.4103/2277-9175.211835.

    Article  PubMed  PubMed Central  Google Scholar 

  55. Roddy E, Thomas MJ, Marshall M, Rathod T, Myers H, Menz HB, et al. The population prevalence of symptomatic radiographic foot osteoarthritis in community-dwelling older adults: cross-sectional findings from the clinical assessment study of the foot. Ann Rheum Dis. 2015;74(1):156–63. https://doi.org/10.1136/annrheumdis-2013-203804.

    Article  PubMed  Google Scholar 

  56. Gates LS, Arden NK, Hannan MT, Roddy E, Gill TK, Hill CL, et al. Prevalence of foot pain across an international consortium of population-based cohorts. Arthritis Care Res (Hoboken). 2019;71(5):661–70. https://doi.org/10.1002/acr.23829.

    Article  Google Scholar 

  57. Keen HI, Redmond A, Wakefield RJ, Freeston J, Grainger AJ, Hensor EM, et al. An ultrasonographic study of metatarsophalangeal joint pain: synovitis, structural pathology and their relationship to symptoms and function. Ann Rheum Dis. 2011;70(12):2140–3. https://doi.org/10.1136/annrheumdis-2011-200349.

    Article  PubMed  Google Scholar 

  58. Iagnocco A, Filippucci E, Riente L, Meenagh G, Delle Sedie A, Sakellariou G, et al. Ultrasound imaging for the rheumatologist XXXV. Sonographic assessment of the foot in patients with osteoarthritis. Clin Exp Rheumatol. 2011;29(5):757–62.

    PubMed  Google Scholar 

  59. Keen HI, Wakefield RJ, Grainger AJ, Hensor EM, Emery P, Conaghan PG. Can ultrasonography improve on radiographic assessment in osteoarthritis of the hands? A comparison between radiographic and ultrasonographic detected pathology. Ann Rheum Dis. 2008;67(8):1116–20. https://doi.org/10.1136/ard.2007.079483.

    Article  CAS  PubMed  Google Scholar 

  60. Draghi F, Urciuoli L, Alessandrino F, Corti R, Scudeller L, Grassi R. Joint effusion of the knee: potentialities and limitations of ultrasonography. J Ultrasound. 2015;18(4):361–71. https://doi.org/10.1007/s40477-015-0180-3.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Keen HI, Mease PJ, Bingham CO 3rd, Giles JT, Kaeley G, Conaghan PG. Systematic review of MRI, ultrasound, and scintigraphy as outcome measures for structural pathology in interventional therapeutic studies of knee arthritis: focus on responsiveness. J Rheumatol. 2011;38(1):142–54. https://doi.org/10.3899/jrheum.100377.

    Article  PubMed  Google Scholar 

  62. Takase K, Ohno S, Takeno M, Hama M, Kirino Y, Ihata A, et al. Simultaneous evaluation of long-lasting knee synovitis in patients undergoing arthroplasty by power Doppler ultrasonography and contrast-enhanced MRI in comparison with histopathology. Clin Exp Rheumatol. 2012;30(1):85–92.

    CAS  PubMed  Google Scholar 

  63. Koski JM, Kamel A, Waris P, Waris V, Tarkiainen I, Karvanen E, et al. Atlas-based knee osteophyte assessment with ultrasonography and radiography: relationship to arthroscopic degeneration of articular cartilage. Scand J Rheumatol. 2016;45(2):158–64. https://doi.org/10.3109/03009742.2015.1055797.

    Article  CAS  PubMed  Google Scholar 

  64. Okano T, Filippucci E, Di Carlo M, Draghessi A, Carotti M, Salaffi F, et al. Ultrasonographic evaluation of joint damage in knee osteoarthritis: feature-specific comparisons with conventional radiography. Rheumatology (Oxford). 2016;55(11):2040–9. https://doi.org/10.1093/rheumatology/kew304.

    Article  Google Scholar 

  65. Steer KJD, Bostick GP, Woodhouse LJ, Nguyen TT, Schankath A, Lambert RGW, et al. Can effusion-synovitis measured on ultrasound or MRI predict response to intra-articular steroid injection in hip osteoarthritis? Skelet Radiol. 2019;48(2):227–37. https://doi.org/10.1007/s00256-018-3010-9.

    Article  CAS  Google Scholar 

  66. Mathiessen A, Haugen IK, Slatkowsky-Christensen B, Boyesen P, Kvien TK, Hammer HB. Ultrasonographic assessment of osteophytes in 127 patients with hand osteoarthritis: exploring reliability and associations with MRI, radiographs and clinical joint findings. Ann Rheum Dis. 2013;72(1):51–6. https://doi.org/10.1136/annrheumdis-2011-201195.

    Article  PubMed  Google Scholar 

  67. Mathiessen A, Slatkowsky-Christensen B, Kvien TK, Hammer HB, Haugen IK. Ultrasound-detected inflammation predicts radiographic progression in hand osteoarthritis after 5 years. Ann Rheum Dis. 2016;75(5):825–30. https://doi.org/10.1136/annrheumdis-2015-207241.

    Article  PubMed  Google Scholar 

  68. Mathiessen A, Slatkowsky-Christensen B, Kvien TK, Haugen IK, Berner HH. Ultrasound-detected osteophytes predict the development of radiographic and clinical features of hand osteoarthritis in the same finger joints 5 years later. RMD Open. 2017;3(2):e000505. https://doi.org/10.1136/rmdopen-2017-000505.

    Article  PubMed  PubMed Central  Google Scholar 

  69. Sivakumaran P, Hussain S, Ciurtin C. Comparison between several ultrasound hand joint scores and conventional radiography in diagnosing hand osteoarthritis. Ultrasound Med Biol. 2018;44(3):544–50. https://doi.org/10.1016/j.ultrasmedbio.2017.11.009.

    Article  PubMed  Google Scholar 

  70. Vlychou M, Koutroumpas A, Alexiou I, Fezoulidis I, Sakkas LI. High-resolution ultrasonography and 3.0 T magnetic resonance imaging in erosive and nodal hand osteoarthritis: high frequency of erosions in nodal osteoarthritis. Clin Rheumatol. 2013;32(6):755–62. https://doi.org/10.1007/s10067-013-2166-x.

    Article  PubMed  Google Scholar 

  71. Wittoek R, Jans L, Lambrecht V, Carron P, Verstraete K, Verbruggen G. Reliability and construct validity of ultrasonography of soft tissue and destructive changes in erosive osteoarthritis of the interphalangeal finger joints: a comparison with MRI. Ann Rheum Dis. 2011;70(2):278–83. https://doi.org/10.1136/ard.2010.134932.

    Article  PubMed  Google Scholar 

  72. Jordan JM, Helmick CG, Renner JB, Luta G, Dragomir AD, Woodard J, et al. Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project. J Rheumatol. 2007;34(1):172–80.

    PubMed  Google Scholar 

  73. Jordan JM, Helmick CG, Renner JB, Luta G, Dragomir AD, Woodard J, et al. Prevalence of hip symptoms and radiographic and symptomatic hip osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project. J Rheumatol. 2009;36(4):809–15. https://doi.org/10.3899/jrheum.080677.

    Article  PubMed  PubMed Central  Google Scholar 

  74. Jordan JM, Linder GF, Renner JB, Fryer JG. The impact of arthritis in rural populations. Arthritis Care Res. 1995;8(4):242–50. https://doi.org/10.1002/art.1790080407.

    Article  CAS  PubMed  Google Scholar 

  75. Alvarez C, Schwartz TA, Savage-Guin S, Bakewell CJ, Kohler MJ, Lin J, et al. Reliability of knee ultrasound in a community based cohort. Osteoarthr Cartil. 2019;27(S1):S335–S6. https://doi.org/10.1016/j.joca.2019.02.741.

    Article  Google Scholar 

  76. Yerich NV, Alvarez C, Schwartz TA, Savage-Guin S, Bakewell CJ, Kohler MJ, et al. Frequency of ultrasound features of knee osteoarthritis and their association with radiographic features and symptoms in a community-based cohort. Arthritis Rheum. 2019;71:443–4.

    Google Scholar 

  77. Yerich NV, Alvarez C, Schwartz TA, Savage-Guin S, Renner JB, Bakewell CJ, et al. A standardized, pragmatic approach to knee ultrasound for clinical research in osteoarthritis: the Johnston County Osteoarthritis Project. ACR Open Rheumatol. 2020;2(7):438–48.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Amanda E. Nelson .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Nelson, A.E. (2021). Ultrasound in Osteoarthritis. In: Kohler, M.J. (eds) Musculoskeletal Ultrasound in Rheumatology Review. Springer, Cham. https://doi.org/10.1007/978-3-030-73555-5_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-73555-5_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-73554-8

  • Online ISBN: 978-3-030-73555-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics